A Study of Taspoglutide Versus Placebo for the Treatment of Patients With Type 2 Diabetes Mellitus Inadequately Controlled With Metformin Plus Pioglitazone.
Public ClinicalTrials.gov record NCT00744367. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Multicenter, Randomized, Double-blind, Placebo-controlled Study to Assess the Safety, Tolerability and Effect of Taspoglutide on Glycemic Control Compared to Placebo in Patients With Type II Diabetes Mellitus Inadequately Controlled With Metformin Plus Pioglitazone
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This 3 arm study will assess the efficacy of taspoglutide on glycemic control (as assessed by HbA1c) in patients with type 2 diabetes mellitus inadequately controlled with metformin plus pioglitazone, compared to placebo after 24 weeks of treatment. Patients will be randomized to one of 3 treatment arms: taspoglutide 10mg once weekly, taspoglutide 20 mg once weekly (after 4 weeks of taspoglutide 10 mg once weekly) or placebo, in addition to their continued stable metformin plus pioglitazone treatment. After the first 24 weeks patients on placebo will be switched to taspoglutide 10mg once weekly or taspoglutide 20mg once weekly (after 4 weeks of taspoglutide 10mg once weekly. The anticipated time on study treatment is 1-2 years, and the target sample size is 100-500 individuals.
Study identification
- NCT ID
- NCT00744367
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 326 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 75 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Oct 2008 (Type not available)
- Primary completion
- Nov 2010 (Actual)
- Completion
- Nov 2010 (Actual)
- Last update posted
- Aug 5, 2016
2008 – 2010
United States locations
- U.S. sites
- 76
- U.S. states
- 32
- U.S. cities
- 71
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Not listed | Birmingham | Alabama | 35209 | — |
| Not listed | Birmingham | Alabama | 35294 | — |
| Not listed | Huntsville | Alabama | 35801 | — |
| Not listed | Muscle Shoals | Alabama | 35661 | — |
| Not listed | Phoenix | Arizona | 85028 | — |
| Not listed | Phoenix | Arizona | 85032 | — |
| Not listed | Buena Park | California | 90620 | — |
| Not listed | Lancaster | California | 93534 | — |
| Not listed | Loma Linda | California | 92354 | — |
| Not listed | Rancho Cucamonga | California | 91730 | — |
| Not listed | Roseville | California | 95661 | — |
| Not listed | San Diego | California | 92161 | — |
| Not listed | Walnut Creek | California | 94598 | — |
| Not listed | Wheat Ridge | Colorado | 80033 | — |
| Not listed | Hamden | Connecticut | 06518 | — |
| Not listed | Washington D.C. | District of Columbia | 20017 | — |
| Not listed | Bradenton | Florida | 34208 | — |
| Not listed | Chiefland | Florida | 32626 | — |
| Not listed | Fort Myers | Florida | 33907 | — |
| Not listed | Gainesville | Florida | 32607 | — |
| Not listed | Hollywood | Florida | 33021 | — |
| Not listed | Miami | Florida | 33136 | — |
| Not listed | New Port Richey | Florida | 34652 | — |
| Not listed | Ocala | Florida | 34474 | — |
| Not listed | Plantation | Florida | 33317 | — |
| Not listed | Tampa | Florida | 33614 | — |
| Not listed | Nampa | Idaho | 83687 | — |
| Not listed | Aurora | Illinois | 60504 | — |
| Not listed | Libertyville | Illinois | 60048 | — |
| Not listed | Evansville | Indiana | 47714 | — |
| Not listed | Des Moines | Iowa | 50314 | — |
| Not listed | Topeka | Kansas | 66614 | — |
| Not listed | Lexington | Kentucky | 40504 | — |
| Not listed | Madisonville | Kentucky | 42431 | — |
| Not listed | New Orleans | Louisiana | 70121 | — |
| Not listed | Frederick | Maryland | 21702 | — |
| Not listed | Oxon Hill | Maryland | 20745 | — |
| Not listed | Detroit | Michigan | 48202 | — |
| Not listed | Ferndale | Michigan | 48220 | — |
| Not listed | Kalamazoo | Michigan | 49048 | — |
| Not listed | Biloxi | Mississippi | 39531 | — |
| Not listed | Olive Branch | Mississippi | 38654 | — |
| Not listed | City of Saint Peters | Missouri | 63376 | — |
| Not listed | Omaha | Nebraska | 68114 | — |
| Not listed | Omaha | Nebraska | 68131 | — |
| Not listed | Las Vegas | Nevada | 89148 | — |
| Not listed | Albany | New York | 12206-1098 | — |
| Not listed | Brooklyn | New York | 11218 | — |
| Not listed | Hudson | New York | 12534 | — |
| Not listed | Lake Success | New York | 11042 | — |
| Not listed | Staten Island | New York | 10301 | — |
| Not listed | Charlotte | North Carolina | 28262 | — |
| Not listed | Charlotte | North Carolina | 28277 | — |
| Not listed | Mooresville | North Carolina | 28117 | — |
| Not listed | Wilmington | North Carolina | 28401 | — |
| Not listed | Bismarck | North Dakota | 58501 | — |
| Not listed | Athens | Ohio | 45701 | — |
| Not listed | Cincinnati | Ohio | 45219 | — |
| Not listed | Kettering | Ohio | 45429 | — |
| Not listed | Norman | Oklahoma | 73071 | — |
| Not listed | Medford | Oregon | 97504 | — |
| Not listed | Beaver | Pennsylvania | 15009 | — |
| Not listed | Bensalem | Pennsylvania | 19020 | — |
| Not listed | Carlisle | Pennsylvania | 17015 | — |
| Not listed | Levittown | Pennsylvania | 19056 | — |
| Not listed | Melrose Park | Pennsylvania | 19027 | — |
| Not listed | Pittsburgh | Pennsylvania | 15236 | — |
| Not listed | Cranston | Rhode Island | 02920 | — |
| Not listed | Greer | South Carolina | 29651 | — |
| Not listed | Bellaire | Texas | 77401 | — |
| Not listed | Dallas | Texas | 75230 | — |
| Not listed | Dallas | Texas | 75231 | — |
| Not listed | Houston | Texas | 77030 | — |
| Not listed | San Antonio | Texas | 78205 | — |
| Not listed | Salt Lake City | Utah | 84102 | — |
| Not listed | Federal Way | Washington | 98003 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 37 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00744367, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Aug 5, 2016 · Synced Oct 25, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00744367 live on ClinicalTrials.gov.