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Terminated Phase 2 Interventional

Oral Tonapofylline (BG9928) in Patients With Heart Failure and Renal Insufficiency

ClinicalTrials.gov ID: NCT00745316

Public ClinicalTrials.gov record NCT00745316. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 29, 2026, 11:45 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study to Assess the Safety and Tolerability of Oral Tonapofylline in Patients With Heart Failure and Renal Insufficiency

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The main purpose of this study is to determine the safety and tolerability of tonapofylline (BG9928) when given at different doses to patients with heart failure and renal insufficiency. This study will also explore: * Disease related quality-of-life * Exercise capacity * Renal function * Concomitant medications

Study identification

NCT ID
NCT00745316
Recruitment status
Terminated
Study type
Interventional
Phase
Phase 2
Lead sponsor
Biogen
Industry
Enrollment
34 participants

Conditions and interventions

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Feb 2009 (Type not available)
Primary completion
Jan 2010 (Actual)
Completion
Jan 2010 (Actual)
Last update posted
Sep 11, 2023

2009 – 2010

United States locations

U.S. sites
30
U.S. states
21
U.S. cities
28
Facility City State ZIP Site status
Not listed Huntsville Alabama 35801 —
Not listed Mobile Alabama 36608 —
Not listed Scottsdale Arizona 85251 —
Not listed Tucson Arizona 85710 —
Not listed Beverly Hills California 90210 —
Not listed San Diego California 92103 —
Not listed Denver Colorado 80218 —
Not listed Bridgeport Connecticut 06606 —
Not listed Jacksonville Florida 32209 —
Not listed Melbourne Florida 32901 —
Not listed Ormond Beach Florida 32174 —
Not listed Chicago Illinois 60612 —
Not listed Maywood Illinois 60153 —
Not listed Indianapolis Indiana 46260 —
Not listed Iowa City Iowa 52242 —
Not listed Owensboro Kentucky 42303 —
Not listed Baltimore Maryland 21201 —
Not listed Boston Massachusetts 02114 —
Not listed Boston Massachusetts 02115 —
Not listed Minneapolis Minnesota 55415 —
Not listed Lincoln Nebraska 68506 —
Not listed The Bronx New York 10461 —
Not listed Cincinnati Ohio 45219 —
Not listed Cincinnati Ohio 45267 —
Not listed Oklahoma City Oklahoma 73120 —
Not listed Lancaster Pennsylvania 17602 —
Not listed Germantown Tennessee 38138 —
Not listed Roanoke Virginia 24014 —
Not listed Beloit Wisconsin 53511 —
Not listed Madison Wisconsin 53792 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00745316, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Sep 11, 2023 · Synced Oct 29, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT00745316 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →