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Completed Phase 3 Interventional Results available

Aztreonam for Inhalation Solution vs Tobramycin Inhalation Solution in Patients With Cystic Fibrosis & Pseudomonas Aeruginosa

ClinicalTrials.gov ID: NCT00757237

Public ClinicalTrials.gov record NCT00757237. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 3, 2026, 4:05 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

An Open-Label, Randomized, Phase 3 Trial to Evaluate the Efficacy and Safety of Aztreonam for Inhalation Solution (AZLI) Versus Tobramycin Inhalation Solution (TIS) in an Intermittent Aerosolized Antibiotic Regimen in Subjects With Cystic Fibrosis Followed by an Open-Label, Single Arm Extension (European Union [EU] Only)

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The purpose of this study was to assess the comparative safety and effectiveness of aztreonam for inhalation solution versus tobramycin inhalation solution in adult and pediatric patients with cystic fibrosis (CF) and pulmonary Pseudomonas aeruginosa (PA) infection.

Study identification

NCT ID
NCT00757237
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Lead sponsor
Gilead Sciences
Industry
Enrollment
274 participants

Conditions and interventions

Eligibility (public fields only)

Age range
6 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jul 31, 2008
Primary completion
Apr 30, 2010
Completion
Oct 31, 2010
Last update posted
Jul 3, 2011

2008 – 2010

United States locations

U.S. sites
29
U.S. states
18
U.S. cities
28
Facility City State ZIP Site status
Not listed Anchorage Alaska 99508
Not listed Phoenix Arizona 85006
Not listed Tuscon Arizona 85724
Not listed Orange California 92868
Not listed Aurora Colorado 80045
Not listed Denver Colorado 80206
Not listed Wilmington Delaware 19803
Not listed Orlando Florida 32801
Not listed Tampa Florida 33606
Not listed Chicago Illinois 60637
Not listed Glenview Illinois 60025
Not listed Niles Illinois 60714
Not listed Boston Massachusetts 02115
Not listed Columbia Missouri 65212
Not listed Las Vegas Nevada 89107
Not listed Albany New York 12208
Not listed New Hyde Park New York 11040
Not listed Cincinnati Ohio 45229
Not listed Dayton Ohio 45404
Not listed Toledo Ohio 43606
Not listed Oklahoma City Oklahoma 73112
Not listed Hershey Pennsylvania 17033
Not listed Philadelphia Pennsylvania 19102
Not listed Philadelphia Pennsylvania 19104
Not listed Charleston South Carolina 29425
Not listed Houston Texas 77030
Not listed San Antonio Texas 78212
Not listed Salt Lake City Utah 84132
Not listed Richmond Virginia 23298

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 63 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00757237, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jul 3, 2011 · Synced Sep 3, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT00757237 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →