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Terminated Phase 2 Interventional

Naltrexone SR and Fluoxetine Combination Therapy in Subjects With Obsessive-Compulsive Disorder

ClinicalTrials.gov ID: NCT00758966

Public ClinicalTrials.gov record NCT00758966. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Nov 2, 2026, 3:21 PM EST

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Proof-of-Concept, Multicenter, Randomized, Double-Blind, Parallel Study of Naltrexone Sustained-Release (SR) and/or Fluoxetine Therapy in the Treatment of Subjects With Obsessive-Compulsive Disorder (OCD)

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The purpose of this study is to determine if the combination of naltrexone SR and fluoxetine is more effective in treating the symptoms of obsessive-compulsive disorder (OCD)than either fluoxetine alone or naltrexone SR alone.

Study identification

NCT ID
NCT00758966
Recruitment status
Terminated
Study type
Interventional
Phase
Phase 2
Lead sponsor
Orexigen Therapeutics, Inc
Industry
Enrollment
8 participants

Conditions and interventions

Eligibility (public fields only)

Age range
18 Years to 60 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Sep 2008 (Type not available)
Primary completion
Dec 2008 (Actual)
Completion
Dec 2008 (Actual)
Last update posted
Nov 29, 2012

2008

United States locations

U.S. sites
11
U.S. states
10
U.S. cities
11
Facility City State ZIP Site status
Synergy Clinical Research National City California 91950 —
California Clinical Trials San Diego California 92123 —
University of Florida, Department of Psychiatry Gainesville Florida 32606 —
Atlanta Center for Medical Research Atlanta Georgia 30308 —
Indiana University School of Medicine Indianapolis Indiana 46202 —
Global Medical Institute, LLC Princeton New Jersey 08540 —
Brooklyn Medical Institute Brooklyn New York 11223 —
Community Research Cincinnati Ohio 45227 —
Summit Research Network, Inc. Portland Oregon 97210 —
Carolina Clinical Research Services Columbia South Carolina 29201 —
Northbrooke Research Center Brown Deer Wisconsin 53223 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00758966, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Nov 29, 2012 · Synced Nov 2, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT00758966 live on ClinicalTrials.gov.

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