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Completed Phase 3 Interventional Results available

Evaluating the Effectiveness of Sildenafil at Improving Health Outcomes and Exercise Ability in People With Diastolic Heart Failure (The RELAX Study)

ClinicalTrials.gov ID: NCT00763867

Public ClinicalTrials.gov record NCT00763867. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 1, 2026, 11:08 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Phosphodiesterase-5 Inhibition to Improve Clinical Status and Exercise Capacity in Diastolic Heart Failure (RELAX)

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

Diastolic heart failure (DHF), which affects older individuals and women at a disproportionate rate, is a condition that can lead to shortness of breath and fluid build-up in the lungs. This study will evaluate the effectiveness of the medication sildenafil at improving exercise ability and health outcomes in people with DHF.

Study identification

NCT ID
NCT00763867
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Lead sponsor
Duke University
Other
Enrollment
216 participants

Conditions and interventions

Conditions

Interventions

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Aug 31, 2008
Primary completion
Aug 31, 2012
Completion
Aug 31, 2012
Last update posted
Jul 22, 2014

2008 – 2012

United States locations

U.S. sites
9
U.S. states
8
U.S. cities
9
Facility City State ZIP Site status
Mayo Clinic Arizona Phoenix Arizona 85054
Morehouse School of Medicine Atlanta Georgia 30310
Brigham and Women's Hospital Boston Massachusetts 02115
Minnesota Heart Failure Network Minneapolis Minnesota 55415
Mayo Clinic Rochester Minnesota 55905
Duke University Medical Center Durham North Carolina 27705
Baylor College of Medicine Houston Texas 77030
University of Utah Health Sciences Center Murray Utah 84107
University of Vermont - Fletcher Allen Health Care Burlington Vermont 05401

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 1 non-U.S. site.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00763867, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jul 22, 2014 · Synced Sep 1, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT00763867 live on ClinicalTrials.gov.

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