ClinicalTrials.gov record
An Open-Label, Long-Term Safety Study of Linaclotide in Patients With Chronic Constipation or Irritable Bowel Syndrome With Constipation
ClinicalTrials.gov ID: NCT00765999
Public ClinicalTrials.gov record NCT00765999. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
An Open-Label, Long-Term Safety Study of Oral Linaclotide Administered to Patients With Chronic Constipation or Irritable Bowel Syndrome With Constipation
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The objective of this study is to assess the long-term safety of linaclotide administered to patients with chronic constipation (CC) or irritable bowel syndrome with constipation (IBS-C).
Study identification
- NCT ID
- NCT00765999
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 1,559 participants
Conditions and interventions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Oct 31, 2008 (Actual)
- Primary completion
- Jan 31, 2012 (Actual)
- Completion
- Jan 31, 2012 (Actual)
- Last update posted
- Feb 15, 2019
2008 – 2012
United States locations
- U.S. sites
- 110
- U.S. states
- 33
- U.S. cities
- 97
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Innovative Clinical Trials | Birmingham | Alabama | 35205 | — |
| Parkway Medical Center | Birmingham | Alabama | 35215 | — |
| Medical Affiliated Research Center, Inc. | Huntsville | Alabama | 35801 | — |
| Radiant Research, Inc. | Chandler | Arizona | 85224 | — |
| Pivotal Research Centers | Peoria | Arizona | 85381 | — |
| Pivotal Research Center | Peoria | Arizona | 85381 | — |
| Carl T Hayden VA Medical Center GI Section-CS-111G | Phoenix | Arizona | 85012 | — |
| Elite Clinical Studies, LLC | Phoenix | Arizona | 85018 | — |
| Radiant Research, Inc. | Scottsdale | Arizona | 85251 | — |
| Genova Clinical Research, Inc. | Tucson | Arizona | 85704 | — |
| Adobe Clinical Research, LLC | Tucson | Arizona | 85712 | — |
| Providence Clinical Research | Burbank | California | 91505 | — |
| Encompass Clinical Research North Coast | Encinitas | California | 92024 | — |
| Family Medical Center | Foothill Ranch | California | 92610 | — |
| Axis Clinical Trials | Los Angeles | California | 90036 | — |
| Facey Medical Foundation | Mission Hills | California | 91345 | — |
| Advanced Clinical Research Institute | Orange | California | 92869 | — |
| Westlake Medical Research | Westlake Village | California | 91361 | — |
| Boulder Medical Center, P.C. | Boulder | Colorado | 80304 | — |
| Lynn Institute of the Rockies | Colorado Springs | Colorado | 80907 | — |
| Colorado Gastroenterology, Prof LLC | Denver | Colorado | 80205 | — |
| Longmont Medical Research Network | Longmont | Colorado | 80501 | — |
| Western States Clinical Research | Wheat Ridge | Colorado | 80033 | — |
| Chase Medical Research, LLC | Waterbury | Connecticut | 06708 | — |
| Clinical Trials Management of Boca Raton, Inc. | Boca Raton | Florida | 33428 | — |
| Meridien Research | Bradenton | Florida | 34208 | — |
| PAB Clinical Research | Brandon | Florida | 33511 | — |
| Meridien Research | Brooksville | Florida | 34601 | — |
| Clinical Physiology Associates Clinical Study Center | Fort Myers | Florida | 33916 | — |
| Jupiter Research, Inc. | Jupiter | Florida | 33458 | — |
| FPA Clinical Research | Kissimmee | Florida | 34741 | — |
| Pharmax Research Clinic | Miami | Florida | 33126 | — |
| United Medical Research | New Smyrna Beach | Florida | 32168 | — |
| RenStar Medical Research | Ocala | Florida | 34471 | — |
| Compass Research | Orlando | Florida | 32806 | — |
| Emerald Coast Research Associates | Panama City | Florida | 32405 | — |
| University Clinical Research, Inc. | Pembroke Pines | Florida | 33024 | — |
| Miami Research Associates | South Miami | Florida | 33143 | — |
| Meridien Research | St. Petersburg | Florida | 33709 | — |
| Meridien Research | Tampa | Florida | 33606 | — |
| Advanced Research Institute | Trinity | Florida | 34655 | — |
| Florida Medical Clinic, P.A. Clinical Research Division | Zephyrhills | Florida | 33542 | — |
| Radiant Research, Inc. | Atlanta | Georgia | 30342 | — |
| Gastrointestinal Specialists of Georgia, PC | Marietta | Georgia | 30060 | — |
| Atlanta Gastroenterology Associates, LLC | Marietta | Georgia | 30067 | — |
| Clinical Research Atlanta | Stockbridge | Georgia | 30281 | — |
| North Georgia Clinical Research | Woodstock | Georgia | 30189 | — |
| Rosemark WomenCare Specialist | Idaho Falls | Idaho | 83404 | — |
| Rockford Gastroenterology Associates, Ltd. | Rockford | Illinois | 61107 | — |
| MediSphere Medical Research Center, LLC | Evansville | Indiana | 47714 | — |
| University of Iowa Hospitals & Clinics | Iowa City | Iowa | 52242 | — |
| Heartland Research Associates, LLC | Arkansas City | Kansas | 67005 | — |
| Heartland Research Associates, LLC | Newton | Kansas | 67114 | — |
| Heartland Research Associates, LLC | Wichita | Kansas | 67205 | — |
| Heartland Research Associates, LLC | Wichita | Kansas | 67207 | — |
| Central Kentucky Research Associates | Lexington | Kentucky | 40509 | — |
| Trover Health System | Madisonville | Kentucky | 42431 | — |
| Medical Development Centers, LLC | Baton Rouge | Louisiana | 70808 | — |
| Clinical Trials of America, Inc. | Shreveport | Louisiana | 71101 | — |
| Metropolitan Gastroenterology Group PC, Chevy Chase Clinical Research | Chevy Chase | Maryland | 20815 | — |
| Meritus Center for Clinical Research | Hagerstown | Maryland | 21742 | — |
| Charm City Research | Towson | Maryland | 21286 | — |
| Boston Clinical Trials | Boston | Massachusetts | 02135 | — |
| Kalamazoo Gastroenterology Hepatology | Kalamazoo | Michigan | 49048 | — |
| Ridgeview Research Two Twelve Medical Center | Chaska | Minnesota | 55318 | — |
| St. Louis Center for Clinical Research | St Louis | Missouri | 63128 | — |
| The Gastroenterology Group of S.J. | Vineland | New Jersey | 08360 | — |
| New Mexico Clinical Research and Osteoporosis Center | Albuquerque | New Mexico | 87106 | — |
| Lifeline Research Institute | Brooklyn | New York | 11214 | — |
| Long Island Clinical Research Associates, LLP | Great Neck | New York | 11021 | — |
| Long Island Gastrointestinal Research Group | Great Neck | New York | 11023 | — |
| Gastrointestinal Research Associates, LLC | Setauket | New York | 11733 | — |
| MediSpect, LLC | Boone | North Carolina | 28607 | — |
| Cumberland Research Associates, LLC | Fayetteville | North Carolina | 28304 | — |
| LeBauer Research Associates, P.A. | Greensboro | North Carolina | 27403 | — |
| Clinical Trials of America, INC | Hickory | North Carolina | 28601 | — |
| Wake Research Associates, LLC | Raleigh | North Carolina | 27612 | — |
| Hanover Medical Specialists, PA | Wilmington | North Carolina | 28401 | — |
| Digestive Health Specialists, PA | Winston-Salem | North Carolina | 27103 | — |
| Consultants for Clinical Research | Cincinnati | Ohio | 45219 | — |
| Rapid Medical Research, Inc. | Cleveland | Ohio | 44122 | — |
| Remington Davis | Columbus | Ohio | 43215 | — |
| Hometown Urgent Care and Research | Dayton | Ohio | 45432 | — |
| Oklahoma Foundation for Digestive Research | Oklahoma City | Oklahoma | 73104 | — |
| Gastroenterology United of Tulsa | Tulsa | Oklahoma | 74135 | — |
| Clinical Trials Research Services, LLC | Pittsburgh | Pennsylvania | 15206 | — |
| Upstate Pharmaceutical Research | Greenville | South Carolina | 29615 | — |
| Mountain View Clinical Research | Greer | South Carolina | 29651 | — |
| Radiant Research | Greer | South Carolina | 29651 | — |
| Nashville Medical Research Institute | Nashville | Tennessee | 37205 | — |
| Professional Quality Research, Inc. | Austin | Texas | 78705 | — |
| Research Across America RHD Professional Plaza IV | Dallas | Texas | 75234 | — |
| Houston Digestive Diseases Clinic | Houston | Texas | 77090 | — |
| Houston Medical Research Associates | Houston | Texas | 77090 | — |
| R/D Clinical Research, Inc. | Lake Jackson | Texas | 77566 | — |
| Quality Research Inc. | San Antonio | Texas | 78209 | — |
| Diagnostics Research Group | San Antonio | Texas | 78229 | — |
| Fatigue Consultation Clinic | Salt Lake City | Utah | 84102 | — |
| Department of Gastroenterology University of Utah Hospital | Salt Lake City | Utah | 84132 | — |
| Department of Veterans Affairs Research Department | Salt Lake City | Utah | 84148 | — |
| Charlottesville Medical Research | Charlottesville | Virginia | 22911 | — |
| New River Valley Research Institute | Christiansburg | Virginia | 24073 | — |
| Health Research of Hampton Roads | Newport News | Virginia | 23606 | — |
| National Clinical Research - Norfolk, Inc. | Norfolk | Virginia | 23502 | — |
| Clinical Research Associates of Tidewater | Norfolk | Virginia | 23507 | — |
| National Clinical Research-Richmond, Inc. | Richmond | Virginia | 23294 | — |
| Northwest Gastroenterology Associates | Bellevue | Washington | 98004 | — |
| Radiant Research, Inc. | Lakewood | Washington | 98499 | — |
| Wenatchee Valley Medical Center Clinical Research Dept. | Wenatchee | Washington | 98801 | — |
| Aurora Advanced Healthcare, Inc. Clinical Research Center | Milwaukee | Wisconsin | 53209 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 8 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00765999, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Feb 15, 2019 · Synced Oct 21, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00765999 live on ClinicalTrials.gov.