Safety and Efficacy of Mipomersen (ISIS 301012) As Add-on Therapy in High Risk Hypercholesterolemic Patients
Public ClinicalTrials.gov record NCT00770146. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Double-Blind, Placebo-Controlled Study to Assess the Safety and Efficacy of ISIS 301012 (Mipomersen) as Add-on Therapy in High Risk Hypercholesterolemic Patients
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to evaluate the safety and efficacy of dosing with mipomersen for 26 weeks in patients with high cholesterol who are on a maximally tolerated dose of statin and who have a diagnosis that puts them at least at high risk of coronary heart disease (CHD).
Study identification
- NCT ID
- NCT00770146
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 158 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Nov 2008 (Type not available)
- Primary completion
- May 2010 (Actual)
- Completion
- Oct 2010 (Actual)
- Last update posted
- Sep 9, 2016
2008 – 2010
United States locations
- U.S. sites
- 62
- U.S. states
- 23
- U.S. cities
- 54
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Not listed | Birmingham | Alabama | 35209 | — |
| Not listed | Birmingham | Alabama | 35294 | — |
| Not listed | Huntsville | Alabama | 35801 | — |
| Not listed | Muscle Shoals | Alabama | 35662 | — |
| Not listed | Litchfield Park | Arizona | 85340 | — |
| Not listed | Beverly Hills | California | 90211 | — |
| Not listed | Escondido | California | 92025 | — |
| Not listed | Los Angeles | California | 90025 | — |
| Not listed | Mission Viejo | California | 92691 | — |
| Not listed | Newport Beach | California | 92660 | — |
| Not listed | San Diego | California | 92117 | — |
| Not listed | Santa Rosa | California | 95405 | — |
| Not listed | Thousand Oaks | California | 91360 | — |
| Not listed | Westlake Village | California | 91361 | — |
| Not listed | Aventura | Florida | 33180 | — |
| Not listed | Inverness | Florida | 34452 | — |
| Not listed | Jacksonville | Florida | 32216 | — |
| Not listed | Longwood | Florida | 32779 | — |
| Not listed | Miami | Florida | 33143 | — |
| Not listed | Miami | Florida | 33169 | — |
| Not listed | New Port Richey | Florida | 34652 | — |
| Not listed | Pembroke Pines | Florida | 33026 | — |
| Not listed | Pensacola | Florida | 32514 | — |
| Not listed | Ponte Verda | Florida | 32081 | — |
| Not listed | Port Orange | Florida | 32127 | — |
| Not listed | Sandy Springs | Georgia | 30328 | — |
| Not listed | Chicago | Illinois | 60607 | — |
| Not listed | Chicago | Illinois | 60624 | — |
| Not listed | Chicago | Illinois | 60654 | — |
| Not listed | Bloomingtom | Indiana | 47403 | — |
| Not listed | Evansville | Indiana | 47714 | — |
| Not listed | Indianapolis | Indiana | 46254 | — |
| Not listed | Indianapolis | Indiana | 46260 | — |
| Not listed | Louisville | Kentucky | 40213 | — |
| Not listed | Baltimore | Maryland | 21209 | — |
| Not listed | Brockton | Massachusetts | 02301 | — |
| Not listed | New Bedford | Massachusetts | 02740 | — |
| Not listed | Edina | Minnesota | 55435 | — |
| Not listed | Kansas City | Missouri | 64111 | — |
| Not listed | Berlin | New Jersey | 08009 | — |
| Not listed | Johnson City | New York | 13790 | — |
| Not listed | Charlotte | North Carolina | 28204 | — |
| Not listed | Greenville | North Carolina | 27834 | — |
| Not listed | Wilson | North Carolina | 27893 | — |
| Not listed | Cincinnati | Ohio | 45219 | — |
| Not listed | Mentor | Ohio | 44060 | — |
| Not listed | Norman | Oklahoma | 73069 | — |
| Not listed | Tulsa | Oklahoma | 74136 | — |
| Not listed | Portland | Oregon | 97239 | — |
| Not listed | Lansdale | Pennsylvania | 19446 | — |
| Not listed | Murrells Inlet | South Carolina | 29576 | — |
| Not listed | Simpsonville | South Carolina | 29681 | — |
| Not listed | Spartanburg | South Carolina | 29303 | — |
| Not listed | Rapid City | South Dakota | 57702 | — |
| Not listed | Dallas | Texas | 75220 | — |
| Not listed | Dallas | Texas | 75251 | — |
| Not listed | Grapevine | Texas | 76051 | — |
| Not listed | Houston | Texas | 77030 | — |
| Not listed | Houston | Texas | 77074 | — |
| Not listed | Houston | Texas | 77093 | — |
| Not listed | San Antonio | Texas | 78229 | — |
| Not listed | Olympia | Washington | 98502 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00770146, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Sep 9, 2016 · Synced Oct 19, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00770146 live on ClinicalTrials.gov.