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Completed Phase 3 Interventional Accepts healthy volunteers Results available

NINDS CRC Chronic Migraine Treatment Trial

ClinicalTrials.gov ID: NCT00772031

Public ClinicalTrials.gov record NCT00772031. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 21, 2026, 8:30 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

NINDS Clinical Research Collaboration Chronic Migraine Treatment Trial

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The purpose of this study is to compare the reduction in the number of severe headache days at six months in people with chronic migraine treated with topiramate and propranolol versus those treated with topiramate and a placebo.

Study identification

NCT ID
NCT00772031
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Lead sponsor
Anne Lindblad
Industry
Enrollment
191 participants

Conditions and interventions

Interventions

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Accepts healthy volunteers

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Oct 2008 (Type not available)
Primary completion
Sep 2010 (Actual)
Completion
Sep 2010 (Actual)
Last update posted
Jan 24, 2012

2008 – 2010

United States locations

U.S. sites
39
U.S. states
20
U.S. cities
38
Facility City State ZIP Site status
Mayo Clinic 5777 E Mayo Blvd Phoenix Arizona 85054 —
Paradigm Clinical, Inc. 1324 W. Prince Rd Tuscon Arizona 85705 —
Dr. Stephen David Forner - 1405 Magnolia Avenue, Suite B Chico California 95926 —
Shanti Clinical Trials, 1880 West Washington Street Colton California 92324 —
NervPro Research, 15825 Laguna Canyon Road, Suite 202 Irvine California 92618 —
Mercy Medical Group- CHWMF 3000 Q Street, Neurology Sacramento California 95816 —
Health Sciences America, LLC, 1515 N Federal Hwy, Suite 105 Boca Raton Florida 33432 —
Southeast Clinical Research, LLC, 304 NE 1st Street Chiefland Florida 32626 —
Scientific Clinical Research, Inc 1065 NE 125th Street , Ste 417 Miami Florida 33161 —
Neurology Associates of Ormond Beach 8 Mirror Lake Drive Suite A&B Ormond Beach Florida 32174 —
Neurologique Foundation, Inc. 6 Fairfield Blvd. Suite 11 Ponte Vedra Florida 32082 —
Neurology Clinical Research, Inc, 3540 North Pine Island Rd Sunrise Florida 33351 —
Dr. B. Abraham, P.C. 3020 Highway 124 Snellville Georgia 30039 —
Ft. Wayne Neurological Center 7956 W. Jefferson Blvd. Fort Wayne Indiana 46804 —
MidAmerica Neuroscience Research Foundation, 8550 Marshall Dr, Suite 100 Lenexa Kansas 66214 —
Trover Health System Center for Clinical Studies, 200 Clinic Drive Madisonville Kentucky 42431 —
New England Center for Clinical Research (NECCR), 52 Brigham St #7 New Bedford Massachusetts 02740 —
New England Regional Headache Center, Inc 85 Prescott St, Ste 101 Worcester Massachusetts 01605-2982 —
ClinSite, LLC 24 Frank Lloyd Wright Drive, Lobby M Ann Arbor Michigan 48106 —
Anderson & Collins Clinical Research 1 Ethel Road, Suite 106B Edison New Jersey 08817 —
Dent Neurologic Institute, 3980 Sheridan Drive Amherst New York 14226 —
Island Neurological Associates, PC, 824 Old Country Road Plainview New York 11803 —
Schenectady Neurological Consultants 1401 Union Street Schenectady New York 12308 —
Montefiore Headache Center 1575 Blondell Avenue Ste 225 The Bronx New York 10461 —
Mission Neurology, Research Institute Mission Hospital, 509 Biltmore Asheville North Carolina 28801 —
Guilford Neurologic Associates, 1126 North Church Street, Suite 200 Greensboro North Carolina 27401 —
ClinExcel Research 7908 Cincinnati-Dayton Rd, Ste J West Chester Ohio 45069 —
Abington Neurological Associates, Ltd., 1245 Highland Avenue, Ste 301 Abington Pennsylvania 19001 —
Neurology and Sleep Medicine PC, 701 Ostrum Street, Suite 302 Bethlehem Pennsylvania 18015 —
Jefferson Headache Center/Thomas Jefferson Univ. 111 South 11th Street, Suite 8130 Philadelphia Pennsylvania 19107 —
Progress Clinical Trials, 707 Kings Lane Tullahoma Tennessee 37388 —
Texas Neurology, PA, 6301 Gaston Avenue, Suite 400 West Tower Dallas Texas 75214 —
Houston Headache Clinic, 1213 Hermann Drive, Suite 820 Houston Texas 77004 —
Houston Sleep Center, Todd J. Swick, MD, PA, 7500 San Felipe, Suite 525 Houston Texas 77063 —
Protenium Clinical Research, LLC 1725 Chadwick Court Suite 200 Hurst Texas 76054 —
Starlight Clinical Research, 1325 W. South Jordan Pkwy, Ste 101 South Jordan Utah 84095 —
Swedish Pain & Headache Center 101 Madison St, Suite 200 Seattle Washington 98116 —
West Virginia University 1 Medical Center Dr, Box 9180 Morgantown West Virginia 26506 - 9180 —
Gundersen Clinic, Ltd, 1836 South Avenue, MS: EB3-002 La Crosse Wisconsin 54601 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00772031, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jan 24, 2012 · Synced Oct 21, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT00772031 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →