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Terminated Phase 2 Interventional Results available

Lonafarnib in Metastatic Breast Cancer

ClinicalTrials.gov ID: NCT00773474

Public ClinicalTrials.gov record NCT00773474. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 17, 2026, 3:12 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase II Study of Lonafarnib in Patients With Metastatic Breast Cancer

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

A published phase 2 study reported that lonafarnib was administered as a single agent via continuous or intermittent oral dosing to 76 women with advanced breast cancer who were previously treated with chemotherapy and/or with endocrine therapy. Objective response rates of approximately 10% were observed. This study will determine the rate of progression-free survival of patients with metastatic breast cancer who receive lonafarnib.

Study identification

NCT ID
NCT00773474
Recruitment status
Terminated
Study type
Interventional
Phase
Phase 2
Lead sponsor
George Sledge
Other
Enrollment
29 participants

Conditions and interventions

Interventions

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Oct 2008 (Type not available)
Primary completion
Nov 2010 (Actual)
Completion
Nov 2010 (Actual)
Last update posted
Feb 18, 2016

2008 – 2010

United States locations

U.S. sites
6
U.S. states
3
U.S. cities
5
Facility City State ZIP Site status
Medical & Surgical Specialists, LLC Galesburg Illinois 61401 —
Cancer Care Center of Southern Indiana Bloomington Indiana 47403 —
Indiana University Melvin and Bren Simon Cancer Center Indianapolis Indiana 46202 —
Arnett Cancer Care Lafayette Indiana 47904 —
Horizon Oncology Center Lafayette Indiana 47905 —
Ireland Cancer Center - University Hospitals of Cleveland Cleveland Ohio 44106 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00773474, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Feb 18, 2016 · Synced Oct 17, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT00773474 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →