A Study to Evaluate the Efficacy and Safety of Lenalidomide as Maintenance Therapy for Patients With B-Cell Chronic Lymphocytic Leukemia (CLL) Following Second Line Therapy
Public ClinicalTrials.gov record NCT00774345. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3, Multicenter, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study of the Efficacy and Safety of Lenalidomide (Revlimid®) as Maintenance Therapy for Patients With B-Cell Chronic Lymphocytic Leukemia Following Second-Line Therapy (The Continuum Trial)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to determine if lenalidomide (Revlimid®) is safe and effective as a maintenance therapy at improving further the quality of the response you achieved with your last therapy and at prolonging the duration of your response. This study will compare the effects (good and bad) of lenalidomide with the dummy drug.
Study identification
- NCT ID
- NCT00774345
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 317 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jan 27, 2009 (Actual)
- Primary completion
- Oct 27, 2020 (Actual)
- Completion
- Oct 27, 2020 (Actual)
- Last update posted
- Dec 2, 2021
2009 – 2020
United States locations
- U.S. sites
- 56
- U.S. states
- 23
- U.S. cities
- 51
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Mayo Clinic - Arizona | Phoenix | Arizona | 85054 | — |
| Pacific Coast Hematology Oncology | Fountain Valley | California | 92708 | — |
| Kaiser Permanente Medical Group | San Diego | California | 92120 | — |
| Sharp Memorial Hospital | San Diego | California | 92123 | — |
| Stanford University Stanford | Stanford | California | 94305 | — |
| University of Colorado Hospital | Aurora | Colorado | 80045 | — |
| Rocky Mountain Cancer Center | Denver | Colorado | 80218-1210 | — |
| Cancer Center of Central Connecticut | Plainville | Connecticut | 06062 | — |
| Boca Raton Community Hospital | Boca Raton | Florida | 33486 | — |
| Pasco Hernando Oncology Associates, PA | Brooksville | Florida | 34613 | — |
| Memorial Hospital | Hollywood | Florida | 33021 | — |
| Mayo Clinic - Jacksonville | Jacksonville | Florida | 32224 | — |
| Florida Cancer Specialist | Tavares | Florida | 32778 | — |
| Florida Hospital Cancer Institute Waterman | Tavares | Florida | 32778 | — |
| Augusta Oncology Associates, P.C. | Augusta | Georgia | 30901 | — |
| Northwest Georgia Oncology Centers, PCWilliam S. Gibbons Center Research Institute | Marietta | Georgia | 30060 | — |
| Northwestern University, Division of Hematology Oncology, Dept. of Medicine | Chicago | Illinois | 60611 | — |
| Rush University Medical Center | Chicago | Illinois | 60612 | — |
| Ingalls Memorial Hospital | Harvey | Illinois | 60426-3558 | — |
| Edward Hines Jr VA Hospital | Hines | Illinois | 60141 | — |
| North Chicago VA Medical Center | North Chicago | Illinois | 60064 | — |
| Hematology Oncology Assoc. of IL Orchard Research LLC | Skokie | Illinois | 60076 | — |
| Floyd Memorial Cancer Center of Indiana, a division of Floyd Memorial Hospital and Health Services | New Albany | Indiana | 47150 | — |
| McFarland Clinic | Ames | Iowa | 50010 | — |
| Siouxland Hematology-Oncology Associates, LLP | Sioux City | Iowa | 51101-1733 | — |
| Ochsner Medical Institutions | New Orleans | Louisiana | 70121 | — |
| Clinical Unit for Research Trials in Skin CURTIS Massachusetts General Hospital | Boston | Massachusetts | 02114 | — |
| Nevada Cancer Research Foundation | Las Vegas | Nevada | 89106 | — |
| The Cancer Center, Hackensack University Medical Center | Hackensack | New Jersey | 07601 | — |
| Roswell Park Cancer Institute | Buffalo | New York | 14263 | — |
| Winthrop University Hospital | Mineola | New York | 11501 | — |
| Biomedical Research Alliance of New York, LLC | New Hyde Park | New York | 11042 | — |
| SUNY Upstate Medical University Medicine Oncology | Syracuse | New York | 13215 | — |
| Westchester County Medical Center | Valhalla | New York | 10595 | — |
| Wake Forest Univ. Health Sciences Outpatient Comprehensive Cancer Center | Winston-Salem | North Carolina | 27157 | — |
| Gabrail Cancer Center Research | Canton | Ohio | 44718 | — |
| The Christ Hospital | Cincinnati | Ohio | 45219 | — |
| Oncology Hematology Care | Cincinnati | Ohio | 45242 | — |
| University Hospitals Cleveland Medical Center | Cleveland | Ohio | 44106 | — |
| Cleveland Clinic | Cleveland | Ohio | 44195 | — |
| Hematology Oncology Consultants, Inc. | Columbus | Ohio | 43235 | — |
| Gabrail Cancer Center Research | Dover | Ohio | 44622 | — |
| Trilogy Cancer Care | Wooster | Ohio | 44691 | — |
| Kaiser Permanente Northwest Oncology Hematology | Portland | Oregon | 97227 | — |
| Abington Memorial Hospital | Abington | Pennsylvania | 19001 | — |
| Gettysburg Cancer Center | Gettysburg | Pennsylvania | 17325 | — |
| Drexel University, College of Medicine, Clinical Research Group | Philadelphia | Pennsylvania | 19102 | — |
| Western Pennsylvania Hospital | Pittsburgh | Pennsylvania | 15224 | — |
| Abington Hematology Oncology Associates Inc | Willow Grove | Pennsylvania | 19090 | — |
| Charleston Hematology Oncology P.A. | Charleston | South Carolina | 29403 | — |
| M. Francisco Gonzalez, MD, PA | Sumter | South Carolina | 29150 | — |
| Sarah Cannon Cancer Center | Nashville | Tennessee | 37203 | — |
| UT Southwestern Medical Center | Dallas | Texas | 75390 | — |
| Swedish Cancer Institute | Seattle | Washington | 98104 | — |
| Wenatchee Valley Hospital and Clinics | Wenatchee | Washington | 98801 | — |
| Gundersen Clinic Lutheran Hospital | La Crosse | Wisconsin | 54601 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 185 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00774345, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Dec 2, 2021 · Synced Sep 30, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00774345 live on ClinicalTrials.gov.