A Phase II Study of Dasatinib in Children and Adolescents With Newly Diagnosed Chronic Phase Chronic Myelogenous Leukemia (CML) or With Ph+ Leukemias Resistant or Intolerant to Imatinib
Public ClinicalTrials.gov record NCT00777036. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase II Study of Dasatinib Therapy in Children and Adolescents With Newly Diagnosed Chronic Phase Chronic Myelogenous Leukemia or With Ph+ Leukemias Resistant or Intolerant to Imatinib
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to determine whether dasatinib is safe and effective in children and adolescents with newly diagnosed chronic myeloid leukemia (CML), or in children with Ph+ acute lymphoblastic leukemia (ALL), accelerated or blast phases CML who relapse after imatinib or who are resistant or intolerant to imatinib. The side effects of this oral investigational drug in children and adolescents will be evaluated
Study identification
- NCT ID
- NCT00777036
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 133 participants
Conditions and interventions
Eligibility (public fields only)
- Age range
- 1 Day to 18 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Mar 20, 2009 (Actual)
- Primary completion
- Sep 1, 2016 (Actual)
- Completion
- Jan 27, 2025 (Actual)
- Last update posted
- Aug 29, 2025
2009 – 2025
United States locations
- U.S. sites
- 35
- U.S. states
- 12
- U.S. cities
- 14
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Local Institution | Birmingham | Alabama | 35233 | — |
| Local Institution - 0005 | Phoenix | Arizona | 85016 | — |
| Phoenix Children'S Hospital | Phoenix | Arizona | 85016 | — |
| Jonathan Jaques Children'S Cancer Center | Long Beach | California | 90801-1428 | — |
| Jonathan Jaques Children'S Cancer Center | Long Beach | California | 90806 | — |
| Local Institution - 0001 | Long Beach | California | 90806 | — |
| Children'S Hospital Of Orange County | Orange | California | 92868 | — |
| Local Institution - 0024 | Orange | California | 92868 | — |
| Children'S Hospital | Aurora | Colorado | 80045 | — |
| Local Institution - 0004 | Aurora | Colorado | 80045 | — |
| Children's Healthcare Of Atlanta - Egleston | Atlanta | Georgia | 30322 | — |
| Local Institution - 047 | Atlanta | Georgia | 30322 | — |
| Children's Hospital of Chicago | Chicago | Illinois | 60611 | — |
| Local Institution - 0072 | Chicago | Illinois | 60611 | — |
| Local Institution | Chicago | Illinois | 60611 | — |
| Dana Faber Cancer Institute | Boston | Massachusetts | 02215 | — |
| Dana Farber Cancer Institute. | Boston | Massachusetts | 02215 | — |
| Local Institution - 0040 | Boston | Massachusetts | 02215 | — |
| Stephen D. Hassenfeld Children'S Center | New York | New York | 10016 | — |
| Local Institution - 0061 | New York | New York | 10021 | — |
| Memorial Sloan Kettering Cancer Center | New York | New York | 10065 | — |
| Memorial Sloan Kettering Nassau | New York | New York | 10065 | — |
| Oregon Health & Sci Univ | Portland | Oregon | 97239-3098 | — |
| Local Institution - 0002 | Portland | Oregon | 97239 | — |
| Oregon Health & Sci Univ | Portland | Oregon | 97239 | — |
| Children'S Hospital Of Philadelphia | Philadelphia | Pennsylvania | 19104-4318 | — |
| Local Institution - 0014 | Philadelphia | Pennsylvania | 19104-4318 | — |
| Children'S Hospital Of Pittsburgh | Pittsburgh | Pennsylvania | 15224 | — |
| Local Institution - 0003 | Pittsburgh | Pennsylvania | 15224 | — |
| Local Institution - 0035 | Houston | Texas | 77030-4009 | — |
| MD Anderson Cancer Center | Houston | Texas | 77030-4009 | — |
| Local Institution - 0048 | Houston | Texas | 77030 | — |
| Texas Children'S Cancer Center | Houston | Texas | 77030 | — |
| Local Institution - 0028 | Seattle | Washington | 98105 | — |
| Seattle Children'S | Seattle | Washington | 98105 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 139 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00777036, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Aug 29, 2025 · Synced Oct 27, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00777036 live on ClinicalTrials.gov.