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Completed Phase 2 Interventional

AZD6765 Severe Major Depressive Disorder (MDD) IV

ClinicalTrials.gov ID: NCT00781742

Public ClinicalTrials.gov record NCT00781742. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 1, 2026, 7:46 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase IIb, Multicenter, Randomized, Double-blind, Parallel Group, Placebo-controlled Efficacy and Safety Study of Adjunctive AZD6765 in Subjects With Severe Major Depressive Disorder (MDD) and a History of Poor Response to Antidepressants

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The purpose of this research study is to determine whether AZD6765 has an effect on the patient's depression when taken together with current depression medication. In addition, information will be gathered on how well AZD6765 is tolerated, investigate the levels of AZD6765 and the levels of the current depression medication in the blood. In addition, the research staff will determine if AZD6765 has any mood or calming effects (how you feel).

Study identification

NCT ID
NCT00781742
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
AstraZeneca
Industry
Enrollment
152 participants

Conditions and interventions

Interventions

Drug

Eligibility (public fields only)

Age range
18 Years to 65 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Sep 30, 2008
Primary completion
Feb 28, 2010
Completion
Feb 28, 2010
Last update posted
Jul 24, 2012

2008 – 2010

United States locations

U.S. sites
27
U.S. states
15
U.S. cities
27
Facility City State ZIP Site status
Research Site Little Rock Arkansas
Research Site Los Angeles California
Research Site Orange California
Research Site San Diego California
Research Site Santa Ana California
Research Site Hartford Connecticut
Research Site New Haven Connecticut
Research Site Boca Raton Florida
Research Site Gainsville Florida
Research Site Hollywood Florida
Research Site Jacksonville Florida
Research Site Atlanta Georgia
Research Site Roswell Georgia
Research Site Hoffman Estates Illinois
Research Site Joliet Illinois
Research Site Overland Park Kansas
Research Site Lake Charles Louisiana
Research Site Shreveport Louisiana
Research Site Haverhill Massachusetts
Research Site St Louis Missouri
Research Site Willingboro New Jersey
Research Site Albuquerque New Mexico
Research Site Rochester New York
Research Site East Stroudsburg Pennsylvania
Research Site Philadelphia Pennsylvania
Research Site Austin Texas
Research Site Dallas Texas

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00781742, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jul 24, 2012 · Synced Sep 1, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT00781742 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →