Trial of Microplasmin Intravitreal Injection for Non-surgical Treatment of Focal Vitreomacular Adhesion. The MIVI-TRUST (TG-MV-006) Trial.
Public ClinicalTrials.gov record NCT00781859. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Placebo Controlled, Double-masked, Multicenter Trial of Microplasmin Intravitreal Injection for Non-surgical Treatment of Focal Vitreomacular Adhesion
Study identification
- NCT ID
- NCT00781859
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- ThromboGenics
- Industry
- Enrollment
- 326 participants
Conditions and interventions
Conditions
Interventions
- 125 µg Ocriplasmin Drug
- Placebo Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Nov 30, 2008
- Primary completion
- Feb 28, 2010
- Completion
- Mar 31, 2010
- Last update posted
- Dec 16, 2014
2008 – 2010
United States locations
- U.S. sites
- 41
- U.S. states
- 19
- U.S. cities
- 38
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Retinal Consultants of AZ | Phoenix | Arizona | 85014 | — |
| Assocaited Retina Consultants, Ltd. | Phoenix | Arizona | 85020 | — |
| Retina Centers, P.C. | Tucson | Arizona | 85704 | — |
| Retina Vitreous Associate Medical Group | Beverly Hills | California | 90211 | — |
| VMR Institute | Huntington Beach | California | 92647 | — |
| Jules Stein Eye Institute/UCLA | Los Angeles | California | 90095 | — |
| Southern California Desert Retina Consultants | Palm Springs | California | 92262 | — |
| Retinal Consultants Medical Group | Sacramento | California | 95819 | — |
| Rocky Mountain Lions Eye Institute | Aurora | Colorado | 80045-0510 | — |
| Colorado Retina Associates, PC | Denver | Colorado | 80230 | — |
| National Ophthalmologic Research Institute | Fort Meyers | Florida | 33912 | — |
| University of Miami-Bascom Palmer Eye Institute- Palm Beach | Palm Beach | Florida | 33418 | — |
| Sarasota Retina Institute | Sarasota | Florida | 34239 | — |
| Center for Retina and Macular Disease | Winter Haven | Florida | 33880 | — |
| Southeast Retina Center, PC | Augusta | Georgia | 30909 | — |
| Rush University Med. Ctr | Chicago | Illinois | 60612 | — |
| Midwest Eye Institute | Indianapolis | Indiana | 46290 | — |
| Univ. Of Kentuck/Kentucky-Clinic/Dept of Ophthal & VS | Lexington | Kentucky | 40536-0284 | — |
| Maine Vitreoretinal Consultants, LLC, PA | Bangor | Maine | 04401 | — |
| National Retina Institute | Towson | Maryland | 21204 | — |
| University of Michigan-Kellogg Eye Center | Ann Arbor | Michigan | 48105 | — |
| Kresge Eye Institute | Detroit | Michigan | 48201-1423 | — |
| Vitreo-Retinal Associates | Grand Rapids | Michigan | 49525 | — |
| Associated Retina Consultants | Royal Oak | Michigan | 48073 | — |
| Vitroretinal Surgery PA | Minneapolis | Minnesota | 55435 | — |
| Retina Vitreous Centre, PA | New Brunswick | New Jersey | 08901 | — |
| Retina Association of NJ | Teaneck | New Jersey | 07666 | — |
| New York Eye and Ear Infirmary | New York | New York | 10003 | — |
| Columbia University - Harkness Eye Institute | New York | New York | 10032 | — |
| Retina Vitreous Surgeons of Central NY | New York | New York | 13224 | — |
| Duke Eye Center | Durham | North Carolina | 27710 | — |
| Caroline Eye Associates | Southern Pines | North Carolina | 28387 | — |
| Wake Forest University Eye Center | Winston-Salem | North Carolina | 27157 | — |
| Retina Association of Cleveland | Lakewood | Ohio | 44107 | — |
| Pennsylvania Retina Specialists, P.C. | Camp Hill | Pennsylvania | 17011 | — |
| Allegheny Ophthalmic & Orbital Associates, PC | Pittsburgh | Pennsylvania | 15212 | — |
| Souteastern Retina Associates | Kingsport | Tennessee | 37660 | — |
| Austin Retina Associates | Austin | Texas | 78705 | — |
| Vitroretinal Consultants | Houston | Texas | 77030 | — |
| Valley Retina Institute, P.A. | McAllen | Texas | 78503 | — |
| Retinal Consultants of San Antonio | San Antonio | Texas | 78240 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00781859, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Dec 16, 2014 · Synced Jul 21, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT00781859 live on ClinicalTrials.gov.