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Completed Phase 3 Interventional Results available

Trial of Microplasmin Intravitreal Injection for Non-surgical Treatment of Focal Vitreomacular Adhesion. The MIVI-TRUST (TG-MV-006) Trial.

ClinicalTrials.gov ID: NCT00781859

Public ClinicalTrials.gov record NCT00781859. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 22, 2026, 2:34 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Randomized, Placebo Controlled, Double-masked, Multicenter Trial of Microplasmin Intravitreal Injection for Non-surgical Treatment of Focal Vitreomacular Adhesion

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The objective of this trial is to evaluate the safety and efficacy of intravitreal microplasmin 125µg dose in subjects wiht focal vitreomacular adhesion.

Study identification

NCT ID
NCT00781859
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Lead sponsor
ThromboGenics
Industry
Enrollment
326 participants

Conditions and interventions

Interventions

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Dec 2008 (Type not available)
Primary completion
Mar 2010 (Actual)
Completion
Apr 2010 (Actual)
Last update posted
Dec 17, 2014

2008 – 2010

United States locations

U.S. sites
41
U.S. states
19
U.S. cities
38
Facility City State ZIP Site status
Retinal Consultants of AZ Phoenix Arizona 85014 —
Assocaited Retina Consultants, Ltd. Phoenix Arizona 85020 —
Retina Centers, P.C. Tucson Arizona 85704 —
Retina Vitreous Associate Medical Group Beverly Hills California 90211 —
VMR Institute Huntington Beach California 92647 —
Jules Stein Eye Institute/UCLA Los Angeles California 90095 —
Southern California Desert Retina Consultants Palm Springs California 92262 —
Retinal Consultants Medical Group Sacramento California 95819 —
Rocky Mountain Lions Eye Institute Aurora Colorado 80045-0510 —
Colorado Retina Associates, PC Denver Colorado 80230 —
National Ophthalmologic Research Institute Fort Meyers Florida 33912 —
University of Miami-Bascom Palmer Eye Institute- Palm Beach Palm Beach Florida 33418 —
Sarasota Retina Institute Sarasota Florida 34239 —
Center for Retina and Macular Disease Winter Haven Florida 33880 —
Southeast Retina Center, PC Augusta Georgia 30909 —
Rush University Med. Ctr Chicago Illinois 60612 —
Midwest Eye Institute Indianapolis Indiana 46290 —
Univ. Of Kentuck/Kentucky-Clinic/Dept of Ophthal & VS Lexington Kentucky 40536-0284 —
Maine Vitreoretinal Consultants, LLC, PA Bangor Maine 04401 —
National Retina Institute Towson Maryland 21204 —
University of Michigan-Kellogg Eye Center Ann Arbor Michigan 48105 —
Kresge Eye Institute Detroit Michigan 48201-1423 —
Vitreo-Retinal Associates Grand Rapids Michigan 49525 —
Associated Retina Consultants Royal Oak Michigan 48073 —
Vitroretinal Surgery PA Minneapolis Minnesota 55435 —
Retina Vitreous Centre, PA New Brunswick New Jersey 08901 —
Retina Association of NJ Teaneck New Jersey 07666 —
New York Eye and Ear Infirmary New York New York 10003 —
Columbia University - Harkness Eye Institute New York New York 10032 —
Retina Vitreous Surgeons of Central NY New York New York 13224 —
Duke Eye Center Durham North Carolina 27710 —
Caroline Eye Associates Southern Pines North Carolina 28387 —
Wake Forest University Eye Center Winston-Salem North Carolina 27157 —
Retina Association of Cleveland Lakewood Ohio 44107 —
Pennsylvania Retina Specialists, P.C. Camp Hill Pennsylvania 17011 —
Allegheny Ophthalmic & Orbital Associates, PC Pittsburgh Pennsylvania 15212 —
Souteastern Retina Associates Kingsport Tennessee 37660 —
Austin Retina Associates Austin Texas 78705 —
Vitroretinal Consultants Houston Texas 77030 —
Valley Retina Institute, P.A. McAllen Texas 78503 —
Retinal Consultants of San Antonio San Antonio Texas 78240 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00781859, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Dec 17, 2014 · Synced Oct 22, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT00781859 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →