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Completed Phase 3 Interventional Results available

A Study of Nilotinib Versus Imatinib in GIST Patients

ClinicalTrials.gov ID: NCT00785785

Public ClinicalTrials.gov record NCT00785785. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Apr 29, 2026, 10:59 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Randomized, Open Label, Multi-center Phase III Study to Evaluate the Efficacy and Safety of Nilotinib Versus Imatinib in Adult Patients With Unresectable or Metastatic Gastrointestinal Stromal Tumors (GIST)

Study identification

NCT ID
NCT00785785
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Lead sponsor
Novartis Pharmaceuticals
Industry
Enrollment
644 participants

Conditions and interventions

Interventions

  • Nilotinib (AMN107) Drug
  • imatinib (STI571) Drug

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Feb 28, 2009
Primary completion
Sep 30, 2014
Completion
Sep 30, 2014
Last update posted
Jun 15, 2016

2009 – 2014

United States locations

U.S. sites
28
U.S. states
16
U.S. cities
25
Facility City State ZIP Site status
Birmingham Hematology and Oncology Associates Birmingham Alabama 35205
Northern Arizona Hematology/Oncology Associates, P.C. Dept. of No. AZ Hem-Onc Flagstaff Arizona 86001
City of Hope National Medical Center Dept.ofCityofHopeMedicalCtr(4) Duarte California 91010-3000
City of Hope National Medical Center Regulatory Document Duarte California 91010-3000
University of California San Diego - Moores Cancer Center Dept of Moores Cancer Ctr (2) La Jolla California 92093-0658
University of California at Los Angeles GI Oncology Program Los Angeles California 90095
Stanford University Medical Center Stanford Cancer Center Stanford California 94304
University of Colorado Dept. of Univ. of Colorado Aurora Colorado 80045
Rocky Mountain Cancer Centers Dept. of Rocky Mountain Cancer Greenwood Village Colorado
Washington Hospital Center Wash Hospital Washington D.C. District of Columbia 20010
Ocala Oncology Center Dept. of Ocala Oncology Center Ocala Florida 34474
Kootenai Medical Center Dept.ofKootenai Med.Ctr. Coeur d'Alene Idaho 83814
Northwestern University Clinical Research Office (2) Chicago Illinois 60611
Dana Farber Cancer Institute Centerfor Sarcoma&BoneOncology Boston Massachusetts 02215
University of Michigan Comprehensive Cancer Center DeptofMichiganCancerCenter(6) Ann Arbor Michigan 48109-0944
Minnesota Oncology Hematology, P.A. SC Minneapolis Minnesota 55404
Mayo Clinic - Rochester Division of Hematology Rochester Minnesota 55905
New York Oncology Hematology, P.C. NYOH Amsterdam Troy New York 12180
New York Oncology Hematology, P.C. NYOH@AlbanyMedicalCenter(2) Troy New York 12180
University of Pennsylvania Medical Center CAMN107G2301 Philadelphia Pennsylvania 19104-4283
Vanderbilt Univeristy Ingram Cancer Ctr. Nashville Tennessee 37232
Texas Oncology, P.A. Tex Onc (2) Bedford Texas 76022
Texas Oncology Wichita Falls Dallas Texas 75246
University of Texas Southwestern Medical Center DeptofSimmons Cancer Center(3) Dallas Texas 75390-8527
University of Texas/MD Anderson Cancer Center Dept. of MD Anderson (13) Houston Texas 77030-4009
Cancer Care Centers of South Texas / HOAST CCC of So. TX- San Antonio(2) San Antonio Texas 78229
Tyler Cancer Center Dept.ofTylerCancerCtr. (2) Tyler Texas 75702
University of Utah / Huntsman Cancer Institute Dept.ofHuntsmanCancerInst.(3) Salt Lake City Utah 84112

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 137 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00785785, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jun 15, 2016 · Synced Apr 29, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT00785785 live on ClinicalTrials.gov.

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