DME And VEGF Trap-Eye [Intravitreal Aflibercept Injection (IAI;EYLEA®;BAY86-5321)] INvestigation of Clinical Impact
Public ClinicalTrials.gov record NCT00789477. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Double-Masked, Randomized, Controlled Study of the Safety, Tolerability and Biological Effect of Repeated Intravitreal Administration of VEGF Trap-Eye in Patients With Diabetic Macular Edema (DME)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This is a Phase 2, doubled-masked, randomized study of the efficacy and safety of Intravitreal Aflibercept Injection (IAI;EYLEA®;BAY86-5321) in subjects with diabetic macular edema (DME). Approximately 200 subjects will be randomized in the US, Canada, Australia and EU.
Study identification
- NCT ID
- NCT00789477
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 221 participants
Conditions and interventions
Conditions
Interventions
- Laser Photocoagulation Procedure
- Intravitreal Aflibercept Injection Drug
Procedure · Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Dec 2008 (Type not available)
- Primary completion
- Dec 2009 (Actual)
- Completion
- Sep 2010 (Actual)
- Last update posted
- Sep 9, 2014
2008 – 2010
United States locations
- U.S. sites
- 42
- U.S. states
- 21
- U.S. cities
- 41
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Not listed | Artesia | California | 90701 | — |
| Not listed | Beverly Hills | California | 90211 | — |
| Not listed | Mountain View | California | 94040 | — |
| Not listed | Pasadena | California | 91105 | — |
| Not listed | Sacramento | California | 95819 | — |
| Not listed | Santa Ana | California | 92705 | — |
| Not listed | Hamden | Connecticut | 06518 | — |
| Not listed | New London | Connecticut | 06320 | — |
| Not listed | Boynton Beach | Florida | 33426 | — |
| Not listed | Fort Lauderdale | Florida | 33334 | — |
| Not listed | Fort Myers | Florida | 33912 | — |
| Not listed | Ocala | Florida | 34474 | — |
| Not listed | Palm Beach Gardens | Florida | 33410 | — |
| Not listed | Winter Haven | Florida | 33880 | — |
| Not listed | Augusta | Georgia | 30909 | — |
| Not listed | Honolulu | Hawaii | 96815 | — |
| Not listed | Indianapolis | Indiana | 46280 | — |
| Not listed | Bangor | Maine | 04401 | — |
| Not listed | Baltimore | Maryland | 21287 | — |
| Not listed | Boston | Massachusetts | 02114 | — |
| Not listed | Jackson | Michigan | 48104 | — |
| Not listed | Kansas City | Missouri | 64108 | — |
| Not listed | Lincoln | Nebraska | 68506 | — |
| Not listed | New Brunswick | New Jersey | 08901 | — |
| Not listed | Northfield | New Jersey | 08225 | — |
| Not listed | Toms River | New Jersey | 08753 | — |
| Not listed | Rochester | New York | 14620 | — |
| Not listed | Charlotte | North Carolina | 28210 | — |
| Not listed | Raleigh | North Carolina | 27607 | — |
| Not listed | Cincinnati | Ohio | 45243 | — |
| Not listed | Pittsburgh | Pennsylvania | 15213 | — |
| Not listed | Greenville | South Carolina | 29605 | — |
| Not listed | West Columbia | South Carolina | 29169 | — |
| Not listed | Nashville | Tennessee | 37203 | — |
| Not listed | Abilene | Texas | 79606 | — |
| Not listed | Arlington | Texas | 76012 | — |
| Not listed | Austin | Texas | 78705 | — |
| Not listed | Houston | Texas | 77030 | — |
| Not listed | McAllen | Texas | 78503 | — |
| Not listed | San Antonio | Texas | 78215 | — |
| Not listed | San Antonio | Texas | 78240 | — |
| Not listed | Salt Lake City | Utah | 84107 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 5 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00789477, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Sep 9, 2014 · Synced Oct 25, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00789477 live on ClinicalTrials.gov.