Efficacy and Safety of Everolimus (RAD001) in Patients of All Ages With Subependymal Giant Cell Astrocytoma Associated With Tuberous Sclerosis Complex (TSC)(EXIST-1)
Public ClinicalTrials.gov record NCT00789828. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Double-blind, Placebo-controlled Study of Everolimus in the Treatment of Patients With Subependymal Giant Cell Astrocytomas (SEGA) Associated With Tuberous Sclerosis Complex (TSC)
Study identification
- NCT ID
- NCT00789828
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- Novartis Pharmaceuticals
- Industry
- Enrollment
- 117 participants
Conditions and interventions
Interventions
- Everolimus Drug
- Placebo Drug
Drug
Eligibility (public fields only)
- Age range
- Not listed
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jul 31, 2009
- Primary completion
- Feb 28, 2011
- Completion
- Sep 30, 2014
- Last update posted
- Feb 2, 2016
2009 – 2014
United States locations
- U.S. sites
- 12
- U.S. states
- 10
- U.S. cities
- 11
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama at Birmingham | Birmingham | Alabama | 35294 | — |
| Barrow Tuberous Sclerosis Center | Phoenix | Arizona | 85013 | — |
| University of California at Los Angeles | Los Angeles | California | 90048 | — |
| Children's Hospital Oakland Hematology/Oncology Dept | Oakland | California | 94609-1809 | — |
| Children's Healthcare of Atlanta | Atlanta | Georgia | 30342 | — |
| University of CHicago Comer Children's Hospital | Chicago | Illinois | 60637-1470 | — |
| Massachusetts General Hospital Mass General | Boston | Massachusetts | 02114 | — |
| Children's Hospital Boston SC-1 | Boston | Massachusetts | 02115 | — |
| Minnesota Epilepsy Group - PA | Saint Paul | Minnesota | 55102-2383 | — |
| Cincinnati Children's Hospital Medical Center Cincinnati Children's Hosp | Cincinnati | Ohio | 45229-3039 | — |
| Texas Scottish Rite Hospital for Children | Dallas | Texas | 75219 | — |
| Children's Regional Outpatients Center SC | Fairfax | Virginia | 22031 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 12 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00789828, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Feb 2, 2016 · Synced Jul 22, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT00789828 live on ClinicalTrials.gov.