Trial of Microplasmin Intravitreal Injection for Non-Surgical Treatment of Focal Vitreomacular Adhesion. The MIVI-TRUST (TG-MV-007) Trial.
Public ClinicalTrials.gov record NCT00798317. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Placebo Controlled, Double-masked, Multicenter Trial of Microplasmin Intravitreal Injection for Non-surgical Treatment of Focal Vitreomacular Adhesion.
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This trial will evaluate the safety and efficacy of microplasmin, administered as an intravitreal injection, in subjects with focal vitreomacular adhesion. In previously performed clinical trials, some patients treated with intravitreal microplasmin have had resolution of their underlying condition, including macular hole closure, without need for vitrectomy. This clinical trial is justified because the sponsor believes the potential benefits outweigh the potential risks.
Study identification
- NCT ID
- NCT00798317
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 326 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Dec 2008 (Type not available)
- Primary completion
- Jun 2010 (Actual)
- Completion
- Jul 2010 (Actual)
- Last update posted
- Dec 17, 2014
2008 – 2010
United States locations
- U.S. sites
- 20
- U.S. states
- 13
- U.S. cities
- 20
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Retinal Diagnostic Center | Campbell | California | 95008 | — |
| West Coast Retina Group, Inc | San Francisco | California | 94107 | — |
| California Retina Consultants | Santa Barbara | California | 93103 | — |
| Medeye | Miami | Florida | 33143 | — |
| Retina Specialists | Pensacola | Florida | 32503 | — |
| Paducah Retinal Center | Paducah | Kentucky | 42001 | — |
| Tufts Medical Center | Boston | Massachusetts | 02111 | — |
| Vision Research Center at Truman Medical Center | Kansas City | Missouri | 64108 | — |
| Deleware Valley Retina Associates | Lawrenceville | New Jersey | 08648 | — |
| Capital Region Retina | Albany | New York | 12206 | — |
| Southeast Clinical Research Assoicates, PA | Charlotte | North Carolina | 28210 | — |
| Dean A McGee Eye Institute | Oklahoma City | Oklahoma | 73104 | — |
| Scheie Eye Institute, Penn Eye Care | Philadelphia | Pennsylvania | 19104 | — |
| Black Hils regional Eye Institute | Rapid City | South Dakota | 57701 | — |
| Texas Retina Associates | Arlington | Texas | 76012 | — |
| Retina Research Center | Austin | Texas | 78705 | — |
| Retina Consultants | Fort Worth | Texas | 76104 | — |
| Medical Center Ophthalmology Assoc. | San Antonio | Texas | 78240 | — |
| Eye Care Associates | Tyler | Texas | 75701 | — |
| Vitreoretinal Associates | Seattle | Washington | 98104 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 28 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00798317, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Dec 17, 2014 · Synced Oct 21, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00798317 live on ClinicalTrials.gov.