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Completed Phase 2 Interventional Results available

RT, Temozolomide, and Bevacizumab Followed by Bevacizumab/Everolimus in First-line Treatment of GBM

ClinicalTrials.gov ID: NCT00805961

Public ClinicalTrials.gov record NCT00805961. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 25, 2026, 10:33 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase II Study of Concurrent Radiation Therapy, Temozolomide, and Bevacizumab Followed by Bevacizumab/Everolimus in the First-line of Treatment of Patients With Glioblastoma Multiforme

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

In this phase II trial the investigators plan to incorporate two targeted agents, bevacizumab and everolimus, into the first-line multimodality therapy of glioblastoma. In the first portion of the treatment, bevacizumab will be added to standard concurrent radiation therapy plus temozolomide. After completing radiation therapy, patients will continue treatment with the combination of bevacizumab and everolimus.

Study identification

NCT ID
NCT00805961
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Enrollment
68 participants

Conditions and interventions

Interventions

Radiation · Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jan 2009 (Type not available)
Primary completion
Oct 2009 (Actual)
Completion
May 2013 (Actual)
Last update posted
Dec 8, 2021

2009 – 2013

United States locations

U.S. sites
13
U.S. states
11
U.S. cities
13
Facility City State ZIP Site status
Clearview Cancer Institute Huntsville Alabama 35805 —
Florida Cancer Specialists Fort Myers Florida 33901 —
Northeast Georgia Medical Center Gainesville Georgia 30501 —
Consultants in Blood Disorders and Cancer Louisville Kentucky 40207 —
Center for Cancer and Blood Disorders Bethesda Maryland 20817 —
Grand Rapids Clinical Oncology Program Grand Rapids Michigan 49503 —
St. Louis Cancer Care Chesterfield Missouri 63017 —
Research Medical Center Kansas City Missouri 64132 —
Methodist Cancer Center Omaha Nebraska 68114 —
South Carolina Oncology Associates, PA Columbia South Carolina 29210 —
Tennessee Oncology, PLLC Nashville Tennessee 37023 —
Peninsula Cancer Institute Newport News Virginia 23601 —
Virginia Cancer Institute Richmond Virginia 23235 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00805961, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Dec 8, 2021 · Synced Oct 25, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT00805961 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →