A Study of Tocilizumab and Methotrexate Treatment Strategies (Adding Tocilizumab to Methotrexate Versus Switching to Tocilizumab) in Patients With Active Rheumatoid Arthritis With Inadequate Response to Prior Methotrexate Treatment
Public ClinicalTrials.gov record NCT00810199. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Randomized Placebo-controlled Study of Two Treatment Strategies Based on Tocilizumab (TCZ) With or Without Methotrexate (MTX) and Possible Addition of Other Disease-modifying Anti-rheumatic Drugs (DMARDs) in Patients...
Study identification
- NCT ID
- NCT00810199
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- Hoffmann-La Roche
- Industry
- Enrollment
- 556 participants
Conditions and interventions
Conditions
Interventions
- tocilizumab [RoActemra/Actemra] Drug
- methotrexate Drug
- placebo Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Feb 28, 2009
- Primary completion
- Jul 31, 2010
- Completion
- Dec 31, 2012
- Last update posted
- Jul 17, 2014
2009 – 2013
United States locations
- U.S. sites
- 21
- U.S. states
- 11
- U.S. cities
- 21
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Not listed | Santa Monica | California | 90404 | — |
| Not listed | Upland | California | 91786 | — |
| Not listed | Whittier | California | 90606 | — |
| Not listed | Aventura | Florida | 33180 | — |
| Not listed | Naples | Florida | 34102 | — |
| Not listed | Orange Park | Florida | 32073 | — |
| Not listed | Plantation | Florida | 33317 | — |
| Not listed | Sarasota | Florida | 34239 | — |
| Not listed | South Miami | Florida | 33143 | — |
| Not listed | Tamarac | Florida | 33321 | — |
| Not listed | Eagan | Minnesota | 55121 | — |
| Not listed | Las Vegas | Nevada | 89128 | — |
| Not listed | Mayfield | Ohio | 44143 | — |
| Not listed | Middleburg Heights | Ohio | 44130 | — |
| Not listed | Oklahoma City | Oklahoma | 73104 | — |
| Not listed | West Reading | Pennsylvania | 19611 | — |
| Not listed | Greenville | South Carolina | 29601 | — |
| Not listed | Nashville | Tennessee | 37205 | — |
| Not listed | Houston | Texas | 77004 | — |
| Not listed | San Antonio | Texas | 78217 | — |
| Not listed | Spokane | Washington | 99204 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 116 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00810199, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jul 17, 2014 · Synced Jul 22, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT00810199 live on ClinicalTrials.gov.