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Completed Phase 2 Interventional

ADX10059 as an add-on Therapy to Proton Pump Inhibitors (PPIs) in Patients With Gastroesophageal Reflux (GERD)

ClinicalTrials.gov ID: NCT00810485

Public ClinicalTrials.gov record NCT00810485. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 13, 2026, 5:23 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 2B, Randomised, Double-blind, Placebo-controlled, Parallel Group, Dose-ranging, Multi-centre Study to Investigate the Efficacy, Safety and Tolerability of the mGluR5 Negative Allosteric Modulator ADX10059 in Patients With Gastroesophageal Reflux Disease (GERD) Who Are Partial Responders to Proton Pump Inhibitor (PPI) Treatment

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The purpose of this study is to evaluate the effect of ADX10059 in patients with gastroesophageal reflux disease who are partial responders to proton pump inhibitors

Study identification

NCT ID
NCT00810485
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
Addex Pharma S.A.
Industry
Enrollment
298 participants

Conditions and interventions

Eligibility (public fields only)

Age range
18 Years to 70 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Nov 30, 2008
Primary completion
Nov 30, 2009
Completion
Not listed
Last update posted
Jul 15, 2012

Started 2008

United States locations

U.S. sites
28
U.S. states
17
U.S. cities
26
Facility City State ZIP Site status
Not listed Little Rock Arizona
Not listed Tucson Arizona
Not listed Anaheim California
Not listed San Diego California
Not listed Colorado Springs Colorado
Not listed Jacksonville Florida
Not listed Port Orange Florida
Not listed Moline Illinois
54 Kansas City Kansas
62 Kansas City Kansas
Not listed Jackson Mississippi
Not listed Setauket New York
Not listed Harrisburg North Carolina
Not listed High Point North Carolina
Not listed Huntersville North Carolina
Not listed Raleigh North Carolina
Not listed Winston-Salem North Carolina
Not listed Fargo North Dakota
Not listed Cleveland Ohio
Not listed Oklahoma City Oklahoma
Not listed Philadelphia Pennsylvania
Not listed Charleston South Carolina
Not listed Germantown Tennessee
71 Nashville Tennessee
73 Nashville Tennessee
Not listed Baytown Texas
Not listed Houston Texas
Not listed Waukesha Wisconsin

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 12 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00810485, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jul 15, 2012 · Synced Sep 13, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT00810485 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →