Comparative Study of Three NNRTI-Sparing HAART Regimens
Public ClinicalTrials.gov record NCT00811954. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
The ARDENT Study: Atazanavir, Raltegravir, or Darunavir With Emtricitabine/Tenofovir for Naive Treatment
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The U.S. Department of Health and Human Services (HHS) guidelines recommend that HIV infected patients who have never received anti-HIV therapy be treated with a triple drug regimen. The most commonly prescribed and successful regimen contains the medication efavirenz (EFV). However, this regimen may not be an option for everyone, hence alternative regimens are needed. This study was designed to look at how well different combinations of anti-HIV drugs work to decrease the amount of HIV in the blood (viral load) of and allow immune system recovery in people who have never received anti-HIV therapy. This study also examined drug tolerability and safety for the various drug combinations.
Study identification
- NCT ID
- NCT00811954
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 1,814 participants
Conditions and interventions
Conditions
Interventions
- Emtricitabine/tenofovir disoproxil fumarate Drug
- Raltegravir Drug
- Darunavir Drug
- Ritonavir Drug
- Atazanavir Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- May 2009 (Type not available)
- Primary completion
- Jun 2013 (Actual)
- Completion
- Jun 2013 (Actual)
- Last update posted
- Sep 5, 2014
2009 – 2013
United States locations
- U.S. sites
- 55
- U.S. states
- 23
- U.S. cities
- 42
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Alabama Therapeutics CRS | Birmingham | Alabama | 35294-2050 | — |
| Miller Children's Hospital | Long Beach | California | 90806 | — |
| USC CRS | Los Angeles | California | 90033 | — |
| UCLA CARE Center CRS | Los Angeles | California | 90035 | — |
| Stanford CRS | Palo Alto | California | 94304 | — |
| Ucsd, Avrc Crs | San Diego | California | 92103 | — |
| Ucsf Aids Crs | San Francisco | California | 94110 | — |
| Harbor-UCLA Med. Ctr. CRS | Torrance | California | 90502 | — |
| University of Colorado Hospital CRS | Aurora | Colorado | 80045 | — |
| Denver Public Health CRS | Denver | Colorado | 80204 | — |
| Georgetown University CRS (GU CRS) | Washington D.C. | District of Columbia | 20007 | — |
| Howard Univ. Washington DC NICHD CRS | Washington D.C. | District of Columbia | 20060 | — |
| South Florida Childrens Diagnostic & Treatment Cen (5055) | Fort Lauderdale | Florida | 33316 | — |
| University of Florida Jacksonville (5051) | Jacksonville | Florida | 32209 | — |
| Univ. of Miami AIDS CRS | Miami | Florida | 33136 | — |
| The Ponce de Leon Center CRS | Atlanta | Georgia | 30308 | — |
| Northwestern University CRS | Chicago | Illinois | 60611 | — |
| Rush Univ. Med. Ctr. ACTG CRS | Chicago | Illinois | 60612 | — |
| Tulane University New Orleans NICHD CRS (5095) | New Orleans | Louisiana | 70112 | — |
| IHV Baltimore Treatment CRS | Baltimore | Maryland | 21201 | — |
| Johns Hopkins Adult AIDS CRS | Baltimore | Maryland | 21287 | — |
| Massachusetts General Hospital CRS | Boston | Massachusetts | 02114 | — |
| Brigham and Women's Hosp. ACTG CRS | Boston | Massachusetts | 02115 | — |
| Bmc Actg Crs | Boston | Massachusetts | 02118 | — |
| Beth Israel Deaconess Med. Ctr., ACTG CRS | Boston | Massachusetts | 02215 | — |
| Wayne State Univ. CRS | Detroit | Michigan | 48201 | — |
| Henry Ford Hosp. CRS | Detroit | Michigan | 48202 | — |
| Washington U CRS | St Louis | Missouri | 63110 | — |
| Cooper Univ. Hosp. CRS | Camden | New Jersey | 08103 | — |
| New Jersey Medical School- Adult Clinical Research Ctr. CRS | Newark | New Jersey | 07103 | — |
| Cornell CRS | New York | New York | 10011 | — |
| NY Univ. HIV/AIDS CRS | New York | New York | 10016 | — |
| Metropolitan Hospital | New York | New York | 10029 | — |
| HIV Prevention & Treatment CRS | New York | New York | 10032 | — |
| AIDS Care CRS | Rochester | New York | 14607 | — |
| Univ. of Rochester ACTG CRS | Rochester | New York | 14642 | — |
| SUNY Stony Brook NICHD CRS (5040) | Stony Brook | New York | 11794 | — |
| Bronx-Lebanon Hosp. Ctr. CRS | The Bronx | New York | 10457 | — |
| Unc Aids Crs | Chapel Hill | North Carolina | 27514 | — |
| Duke Univ. Med. Ctr. Adult CRS | Durham | North Carolina | 27710 | — |
| Regional Center for Infectious Disease, Wendover Medical Center CRS (3203) | Greensboro | North Carolina | 27401 | — |
| Univ. of Cincinnati CRS | Cincinnati | Ohio | 45267 | — |
| Case CRS | Cleveland | Ohio | 44106 | — |
| Metro Health CRS | Cleveland | Ohio | 44109 | — |
| The Ohio State Univ. AIDS CRS | Columbus | Ohio | 43210 | — |
| The Research & Education Group- Portland CRS (31474) | Portland | Oregon | 97209 | — |
| Hosp. of the Univ. of Pennsylvania CRS | Philadelphia | Pennsylvania | 19104 | — |
| Pitt CRS | Pittsburgh | Pennsylvania | 15213 | — |
| The Miriam Hosp. ACTG CRS | Providence | Rhode Island | 02906 | — |
| St. Jude/UTHSC CRS | Memphis | Tennessee | 38105-2794 | — |
| Vanderbilt Therapeutics CRS | Nashville | Tennessee | 37203 | — |
| Trinity Health and Wellness Center | Dallas | Texas | 75208 | — |
| Houston AIDS Research Team CRS | Houston | Texas | 77030 | — |
| Virginia Commonwealth Univ. Medical Ctr. CRS | Richmond | Virginia | 23219 | — |
| University of Washington AIDS CRS | Seattle | Washington | 98104 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 2 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00811954, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Sep 5, 2014 · Synced Oct 17, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00811954 live on ClinicalTrials.gov.