A Dose-ranging Safety and Efficacy Study of Ecallantide to Reduce Surgical Blood Loss Volume
Public ClinicalTrials.gov record NCT00816023. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
CONSERV-1 (Clinical Outcomes and Safety Trial to Investigate Ecallantide's Effect on Reducing Surgical Blood Loss Volume) A Phase 2 Randomized Placebo-controlled Dose-ranging Study in Subjects Exposed to Cardio-pulmonary Bypass During Primary Coronary Artery Bypass Graft Surgery
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to assess the efficacy and identify the optimal dose(s) of ecallantide in reducing blood loss in subjects undergoing coronary artery bypass surgery including the use of cardio pulmonary bypass.
Study identification
- NCT ID
- NCT00816023
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Lead sponsor
- Cubist Pharmaceuticals LLC, a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)
- Industry
- Enrollment
- 276 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 85 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Feb 28, 2009
- Primary completion
- Nov 30, 2009
- Completion
- Dec 31, 2009
- Last update posted
- Aug 10, 2015
2009 – 2010
United States locations
- U.S. sites
- 21
- U.S. states
- 15
- U.S. cities
- 17
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Cardio-Thoracic Surgeons PC | Birmingham | Alabama | 35205 | — |
| Drug Research and Analysis Corporation | Montgomery | Alabama | 36106 | — |
| University of Colorado - Denver | Aurora | Colorado | 80045 | — |
| Pepin Heart Hospital & Kiran Patel Research Institute | Tampa | Florida | 33613 | — |
| Indiana Ohio Heart | Fort Wayne | Indiana | 46804 | — |
| University of Kentucky | Lexington | Kentucky | 40536 | — |
| Massachusetts General Hospital | Boston | Massachusetts | 02114 | — |
| Caritas St. Elizabeth's Medical Center | Boston | Massachusetts | 02135 | — |
| Beth Israel Deaconess Medical Center | Boston | Massachusetts | 02215 | — |
| MCVI - Covenant Medical Center | Saginaw | Michigan | 48601 | — |
| MCVI - St. Mary's of Michigan | Saginaw | Michigan | 48601 | — |
| Mayo Clinic | Rochester | Minnesota | 55901 | — |
| St. Luke's - Roosevelt Hospital Center | New York | New York | 10025 | — |
| Weill Medical College of Cornell University | New York | New York | 10065 | — |
| Duke University Medical Center | Durham | North Carolina | 27710 | — |
| Integris Baptist Medical Center | Oklahoma City | Oklahoma | 73112 | — |
| East Tennessee Cardiovascular Surgery Group | Knoxville | Tennessee | 37920 | — |
| Texas Heart Institute | Houston | Texas | 77030 | — |
| Sentara Heart Hospital | Norfolk | Virginia | 23507 | — |
| Virginia Commonwealth University | Richmond | Virginia | 23298 | — |
| Charleston Area Medical Center (CAMC) | Charleston | West Virginia | 25304 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 8 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00816023, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Aug 10, 2015 · Synced Sep 4, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT00816023 live on ClinicalTrials.gov.