Efficacy and Safety of Azilsartan Medoxomil and Chlorthalidone in Participants With Moderate to Severe Hypertension
Public ClinicalTrials.gov record NCT00818883. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3, Double-Blind, Randomized, Efficacy and Safety Study of the TAK 491 Plus Chlorthalidone Fixed-Dose Combination Compared With TAK-491 and Hydrochlorothiazide Coadministration Therapy in Subjects With Moderate to Severe Essential Hypertension
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to compare the antihypertensive effect of chlorthalidone vs hydrochlorothiazide when each is used with azilsartan medoxomil, once daily (QD), in participants with moderate to severe essential hypertension.
Study identification
- NCT ID
- NCT00818883
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 609 participants
Conditions and interventions
Conditions
Interventions
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Feb 2009 (Type not available)
- Primary completion
- Nov 2009 (Actual)
- Completion
- Nov 2009 (Actual)
- Last update posted
- Feb 7, 2012
2009
United States locations
- U.S. sites
- 50
- U.S. states
- 22
- U.S. cities
- 50
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Not listed | Birmingham | Alabama | — | — |
| Not listed | Gulf Shores | Alabama | — | — |
| Not listed | Scottsboro | Alabama | — | — |
| Not listed | Gilbert | Arizona | — | — |
| Not listed | Sierra Vista | Arizona | — | — |
| Not listed | Paramount | California | — | — |
| Not listed | Sacramento | California | — | — |
| Not listed | San Diego | California | — | — |
| Not listed | Colorado Springs | Colorado | — | — |
| Not listed | Wheat Ridge | Colorado | — | — |
| Not listed | Milford | Connecticut | — | — |
| Not listed | Adventura | Florida | — | — |
| Not listed | Aventura | Florida | — | — |
| Not listed | Brooksville | Florida | — | — |
| Not listed | Crystal River | Florida | — | — |
| Not listed | DeLand | Florida | — | — |
| Not listed | Doral | Florida | — | — |
| Not listed | Miami | Florida | — | — |
| Not listed | Naranja | Florida | — | — |
| Not listed | Sarasota | Florida | — | — |
| Not listed | Tampa | Florida | — | — |
| Not listed | West Palm Beach | Florida | — | — |
| Not listed | Winter Haven | Florida | — | — |
| Not listed | Atlanta | Georgia | — | — |
| Not listed | Stockbridge | Georgia | — | — |
| Not listed | Suwanee | Georgia | — | — |
| Not listed | Huntsville | Illinois | — | — |
| Not listed | Bloomington | Indiana | — | — |
| Not listed | Valparaiso | Indiana | — | — |
| Not listed | Crestview Hills | Kentucky | — | — |
| Not listed | Lexington | Kentucky | — | — |
| Not listed | West Yarmouth | Massachusetts | — | — |
| Not listed | Ann Arbor | Michigan | — | — |
| Not listed | City of Saint Peters | Missouri | — | — |
| Not listed | St Louis | Missouri | — | — |
| Not listed | New Windsor | New York | — | — |
| Not listed | Asheboro | North Carolina | — | — |
| Not listed | Cincinnati | Ohio | — | — |
| Not listed | Kettering | Ohio | — | — |
| Not listed | Downingtown | Pennsylvania | — | — |
| Not listed | Lancaster | Pennsylvania | — | — |
| Not listed | Lansdale | Pennsylvania | — | — |
| Not listed | Pittsburgh | Pennsylvania | — | — |
| Not listed | Goose Creek | South Carolina | — | — |
| Not listed | Taylors | South Carolina | — | — |
| Not listed | Bryan | Texas | — | — |
| Not listed | San Antonio | Texas | — | — |
| Not listed | Ettrick | Virginia | — | — |
| Not listed | Seattle | Washington | — | — |
| Not listed | Madison | Wisconsin | — | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 3 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00818883, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Feb 7, 2012 · Synced Oct 27, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00818883 live on ClinicalTrials.gov.