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Completed Phase 3 Interventional Results available

Efficacy and Safety of Azilsartan Medoxomil and Chlorthalidone in Participants With Moderate to Severe Hypertension

ClinicalTrials.gov ID: NCT00818883

Public ClinicalTrials.gov record NCT00818883. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced May 14, 2026, 8:35 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 3, Double-Blind, Randomized, Efficacy and Safety Study of the TAK 491 Plus Chlorthalidone Fixed-Dose Combination Compared With TAK-491 and Hydrochlorothiazide Coadministration Therapy in Subjects With Moderate to Severe Essential Hypertension

Study identification

NCT ID
NCT00818883
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Lead sponsor
Takeda
Industry
Enrollment
609 participants

Conditions and interventions

Interventions

  • Azilsartan medoxomil and chlorthalidone Drug
  • Azilsartan medoxomil and hydrochlorothiazide Drug

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jan 31, 2009
Primary completion
Oct 31, 2009
Completion
Oct 31, 2009
Last update posted
Feb 6, 2012

2009

United States locations

U.S. sites
50
U.S. states
22
U.S. cities
50
Facility City State ZIP Site status
Not listed Birmingham Alabama
Not listed Gulf Shores Alabama
Not listed Scottsboro Alabama
Not listed Gilbert Arizona
Not listed Sierra Vista Arizona
Not listed Paramount California
Not listed Sacramento California
Not listed San Diego California
Not listed Colorado Springs Colorado
Not listed Wheat Ridge Colorado
Not listed Milford Connecticut
Not listed Adventura Florida
Not listed Aventura Florida
Not listed Brooksville Florida
Not listed Crystal River Florida
Not listed DeLand Florida
Not listed Doral Florida
Not listed Miami Florida
Not listed Naranja Florida
Not listed Sarasota Florida
Not listed Tampa Florida
Not listed West Palm Beach Florida
Not listed Winter Haven Florida
Not listed Atlanta Georgia
Not listed Stockbridge Georgia
Not listed Suwanee Georgia
Not listed Huntsville Illinois
Not listed Bloomington Indiana
Not listed Valparaiso Indiana
Not listed Crestview Hills Kentucky
Not listed Lexington Kentucky
Not listed West Yarmouth Massachusetts
Not listed Ann Arbor Michigan
Not listed City of Saint Peters Missouri
Not listed St Louis Missouri
Not listed New Windsor New York
Not listed Asheboro North Carolina
Not listed Cincinnati Ohio
Not listed Kettering Ohio
Not listed Downingtown Pennsylvania
Not listed Lancaster Pennsylvania
Not listed Lansdale Pennsylvania
Not listed Pittsburgh Pennsylvania
Not listed Goose Creek South Carolina
Not listed Taylors South Carolina
Not listed Bryan Texas
Not listed San Antonio Texas
Not listed Ettrick Virginia
Not listed Seattle Washington
Not listed Madison Wisconsin

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 3 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00818883, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Feb 6, 2012 · Synced May 14, 2026

Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.

Open the official record

The complete protocol, eligibility criteria, and contact information for NCT00818883 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →