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Completed Phase 2 Interventional Results available

PEAK: Panitumumab Plus mFOLFOX6 vs. Bevacizumab Plus mFOLFOX6 for First Line Treatment of Metastatic Colorectal Cancer (mCRC) Patients With Wild-Type Kirsten Rat Sarcoma-2 Virus (KRAS) Tumors

ClinicalTrials.gov ID: NCT00819780

Public ClinicalTrials.gov record NCT00819780. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 20, 2026, 6:21 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Randomized, Multicenter, Phase 2 Study to Compare the Efficacy of Panitumumab in Combination With mFOLFOX6 to the Efficacy of Bevacizumab in Combination With mFOLFOX6 in Patients With Previously Untreated, KRAS Wild-Type, Unresectable, Metastatic Colorectal Cancer

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The primary objective of this study is to estimate the treatment effect on progression-free survival (PFS) of panitumumab relative to bevacizumab in combination with mFOLFOX6 chemotherapy as first-line therapy in patients with tumors expressing wild-type KRAS, unresectable mCRC.

Study identification

NCT ID
NCT00819780
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
Amgen
Industry
Enrollment
285 participants

Conditions and interventions

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Apr 24, 2009 (Actual)
Primary completion
May 30, 2012 (Actual)
Completion
Jul 7, 2016 (Actual)
Last update posted
Dec 6, 2022

2009 – 2016

United States locations

U.S. sites
63
U.S. states
26
U.S. cities
62
Facility City State ZIP Site status
Research Site Birmingham Alabama 35205 —
Research Site Huntsville Alabama 35805 —
Research Site Berkeley California 94704 —
Research Site Beverly Hills California 90211 —
Research Site Burbank California 91505 —
Research Site Fountain Valley California 92708 —
Research Site La Verne California 91750 —
Research Site Orange California 92868 —
Research Site Riverside California 92501 —
Research Site Roseville California 95661 —
Research Site Denver Colorado 80218 —
Research Site Stamford Connecticut 06902 —
Research Site Waterbury Connecticut 06708 —
Research Site Boynton Beach Florida 33435 —
Research Site Coral Springs Florida 33065 —
Research Site Daytona Beach Florida 32114 —
Research Site Hollywood Florida 33021 —
Research Site Lake Worth Florida 33467 —
Research Site Alpharetta Georgia 30005 —
Research Site Augusta Georgia 30901 —
Research Site Savannah Georgia 31405 —
Research Site Post Falls Idaho 83854 —
Research Site Gurnee Illinois 60031 —
Research Site Peoria Illinois 61615 —
Research Site Indianapolis Indiana 46237 —
Research Site Overland Park Kansas 66210 —
Research Site Wichita Kansas 67214 —
Research Site Danville Kentucky 40422 —
Research Site Hazard Kentucky 41701 —
Research Site Paducah Kentucky 42003 —
Research Site Baltimore Maryland 21204 —
Research Site Bethesda Maryland 20817 —
Research Site Boston Massachusetts 02111 —
Research Site Kalamazoo Michigan 49048 —
Research Site Lambertville Michigan 48144 —
Research Site Lansing Michigan 48912 —
Research Site Mountain Lakes New Jersey 07046 —
Research Site Sparta New Jersey 07871 —
Research Site Albuquerque New Mexico 87131 —
Research Site Buffalo New York 14215 —
Research Site East Setauket New York 11733 —
Research Site Staten Island New York 10301 —
Research Site Huntersville North Carolina 28078 —
Research Site Raleigh North Carolina 27607 —
Research Site Akron Ohio 44304 —
Research Site Columbus Ohio 43228 —
Research Site Hershey Pennsylvania 17033 —
Research Site Philadelphia Pennsylvania 19106 —
Research Site Greenville South Carolina 29605 —
Research Site Mt. Pleasant South Carolina 29464 —
Research Site Memphis Tennessee 38120 —
Research Site Austin Texas 78759 —
Research Site Corpus Christi Texas 78463 —
Research Site Dallas Texas 75231 —
Research Site Round Rock Texas 78665 —
Research Site Temple Texas 76508 —
Research Site Tyler Texas 75702 —
Research Site White River Junction Vermont 05009 —
Research Site Chesapeake Virginia 23320 —
Research Site Newport News Virginia 23601 —
Research Site Newport News Virginia 23606 —
Research Site Spokane Washington 99218 —
Research Site Vancouver Washington 98684 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 32 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00819780, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Dec 6, 2022 · Synced Oct 20, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT00819780 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →