A Phase 2B Multicenter, Randomized, Comparative Trial Of UK-453,061 Versus Etravirine In Combination With Darunavir/Ritonavir And A Nucleos(t)Ide Reverse Transcriptase Inhibitor For The Treatment Of Antiretroviral Experienced HIV-1 Infected Subjects With Evidence Of NNRTI Resistant HIV-1
Public ClinicalTrials.gov record NCT00823979. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2b Multicenter, Randomized, Comparative Trial Of Uk-453,061 Versus Etravirine In Combination With Darunavir/Ritonavir And A Nucleotide/Nucleoside Reverse Transcriptase Inhibitor For The Treatment Of Antiretroviral Experienced Hiv-1 Infected Subjects With Evidence Of Nnrti Resistant Hiv-1
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This is a 96 week study to determine if UK- 453,061 in combination with Darunavir /ritonavir and a Nucleos(t)ide Reverse Transcriptase inhibitor is as efficacious, safe and tolerable as etravirine in combination with Darunavir /ritonavir and a Nucleos(t)ide Reverse Transcriptase inhibitor in HIV-1 infected patients who have been previously treated with antiretroviral drugs and have NNRTI resistance mutations.
Study identification
- NCT ID
- NCT00823979
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 105 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 65 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Mar 24, 2009
- Primary completion
- Oct 17, 2012
- Completion
- Oct 17, 2012
- Last update posted
- Dec 3, 2018
2009 – 2012
United States locations
- U.S. sites
- 21
- U.S. states
- 8
- U.S. cities
- 17
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Jeffrey Goodman Special Care Clinic | Los Angeles | California | 90028 | — |
| Office of Anthony Mills, MD, Inc. | Los Angeles | California | 90069 | — |
| CARES | Sacramento | California | 95814 | — |
| University of California Davis Medical Center | Sacramento | California | 95817 | — |
| San Francisco Veterans Affairs Medical Center | San Francisco | California | 94121 | — |
| The Kinder Medical Group | Miami | Florida | 33133 | — |
| Care Resource | Miami | Florida | 33137 | — |
| Orlando Immunology Center | Orlando | Florida | 32803 | — |
| Infectious Diseases Associates of Northwest Florida, PA | Pensacola | Florida | 32504 | — |
| Hillsborough County Health Department | Tampa | Florida | 33602 | — |
| AIDS Research Consortium of Atlanta | Atlanta | Georgia | 30308 | — |
| Ruth M. Rothstein CORE Center | Chicago | Illinois | 60612 | — |
| Nassau University Medical Center | East Meadow | New York | 11554 | — |
| Greiger Clinic | Mount Vernon | New York | 10550 | — |
| Rosedale Infectious Diseases | Huntersville | North Carolina | 28078 | — |
| University of Cincinnati Medical Center | Cincinnati | Ohio | 45267-0405 | — |
| Saint Hope Foundation - Bellaire Clinic | Bellaire | Texas | 77401 | — |
| Saint Hope Foundation - Conroe Clinic | Conroe | Texas | 77301 | — |
| Nicholaos C. Bellos, MD, PA | Dallas | Texas | 75204 | — |
| University of Texas Southwestern Medical Center at Dallas | Dallas | Texas | 75235 | — |
| Saint Hope Foundation - Stafford Clinic | Stafford | Texas | 77477 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 42 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00823979, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Dec 3, 2018 · Synced Sep 2, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT00823979 live on ClinicalTrials.gov.