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Completed Phase 3 Interventional

A Study of Taspoglutide Versus Placebo for the Treatment of Obese Patients With Type 2 Diabetes Mellitus Inadequately Controlled With Metformin Monotherapy

ClinicalTrials.gov ID: NCT00823992

Public ClinicalTrials.gov record NCT00823992. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 3, 2026, 5:28 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Randomized, Double-blind, Placebo-controlled Study to Assess the Effect of Taspoglutide on Glycemic Control, and Its Safety and Tolerability, in Obese Patients With Type 2 Diabetes Mellitus Inadequately Controlled With Metformin Monotherapy.

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

This 2 arm study will assess the efficacy, safety and tolerability of taspoglutide compared to placebo in obese patients with type 2 diabetes mellitus inadequately controlled with metformin monotherapy. Patients will be randomized to receive taspoglutide (10mg sc once weekly for 4 weeks followed by 20mg once weekly) or placebo sc, in addition to their prescribed, pre-existing metformin therapy.After the first 24 weeks, patients on placebo will be switched to taspoglutide 20mg once weekly (after 4 weeks on taspoglutide 10mg once weekly) The anticipated time on study treatment is 12 months, and the target sample size is 100-500 individuals.

Study identification

NCT ID
NCT00823992
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Lead sponsor
Hoffmann-La Roche
Industry
Enrollment
305 participants

Conditions and interventions

Interventions

Drug

Eligibility (public fields only)

Age range
18 Years to 75 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Dec 31, 2008
Primary completion
Apr 30, 2010
Completion
Apr 30, 2010
Last update posted
Jul 27, 2016

2009 – 2010

United States locations

U.S. sites
29
U.S. states
18
U.S. cities
29
Facility City State ZIP Site status
Not listed Bermuda Dunes California 92203
Not listed La Jolla California 92037
Not listed Los Angeles California 90057
Not listed Mission Viejo California 92691
Not listed Brooksville Florida 34601
Not listed Miami Florida 33133
Not listed St. Petersburg Florida 33709
Not listed Atlanta Georgia 30342
Not listed Chicago Illinois 60607
Not listed Avon Indiana 46123
Not listed New Orleans Louisiana 70121
Not listed Bangor Maine 04401
Not listed Royal Oak Michigan 48073
Not listed Picayune Mississippi 39466
Not listed Clifton New Jersey 07012
Not listed Toms River New Jersey 08753
Not listed Albuquerque New Mexico 87131
Not listed New York New York 10025
Not listed Springfield Gardens New York 11413
Not listed Charlotte North Carolina 28277
Not listed Shelby North Carolina 28150
Not listed Norman Oklahoma 73069
Not listed Medford Oregon 97504
Not listed Clinton South Carolina 29325
Not listed Kingsport Tennessee 37660
Not listed Dallas Texas 75246
Not listed Houston Texas 77074
Not listed Midland Texas 79707
Not listed San Antonio Texas 78237

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 42 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00823992, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jul 27, 2016 · Synced Sep 3, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT00823992 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →