ClinicalTrials.gov record
Sorafenib and Bevacizumab in Treating Patients With Metastatic Colorectal Cancer
ClinicalTrials.gov ID: NCT00826540
Public ClinicalTrials.gov record NCT00826540. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Phase II Study of Sorafenib/Avastin® as Salvage Therapy in Patients With Metastatic Colorectal Cancer
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This phase II trial is studying how well giving sorafenib together with bevacizumab works in treating patients with metastatic colorectal cancer. Sorafenib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Monoclonal antibodies, such as bevacizumab, can block tumor growth in different ways. Some block the ability of tumor cells to grow and spread. Others find tumor cells and help kill them or carry tumor-killing substances to them. Sorafenib and bevacizumab may also stop the growth of tumor cells by blocking blood flow to the tumor. Giving sorafenib together with bevacizumab may kill more tumor cells
Study identification
- NCT ID
- NCT00826540
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 83 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Aug 31, 2009
- Primary completion
- Dec 31, 2009
- Completion
- Jan 31, 2014
- Last update posted
- Jan 19, 2026
2009 – 2014
United States locations
- U.S. sites
- 211
- U.S. states
- 18
- U.S. cities
- 137
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Mayo Clinic in Arizona | Scottsdale | Arizona | 85259 | — |
| The Medical Center of Aurora | Aurora | Colorado | 80012 | — |
| Boulder Community Hospital | Boulder | Colorado | 80301 | — |
| Penrose-Saint Francis Healthcare | Colorado Springs | Colorado | 80907 | — |
| Saint Anthony Central Hospital | Denver | Colorado | 80204 | — |
| Porter Adventist Hospital | Denver | Colorado | 80210 | — |
| Exempla Saint Joseph Hospital | Denver | Colorado | 80218 | — |
| Presbyterian - Saint Lukes Medical Center - Health One | Denver | Colorado | 80218 | — |
| Rose Medical Center | Denver | Colorado | 80220 | — |
| Colorado Cancer Research Program CCOP | Denver | Colorado | 80224-2522 | — |
| Swedish Medical Center | Englewood | Colorado | 80110 | — |
| Saint Mary's Hospital and Regional Medical Center | Grand Junction | Colorado | 81502 | — |
| North Colorado Medical Center | Greeley | Colorado | 80631 | — |
| Sky Ridge Medical Center | Lone Tree | Colorado | 80124 | — |
| Longmont United Hospital | Longmont | Colorado | 80501 | — |
| McKee Medical Center | Loveland | Colorado | 80539 | — |
| Saint Mary Corwin Medical Center | Pueblo | Colorado | 81004 | — |
| North Suburban Medical Center | Thornton | Colorado | 80229 | — |
| Exempla Lutheran Medical Center | Wheat Ridge | Colorado | 80033 | — |
| Mayo Clinic in Florida | Jacksonville | Florida | 32224-9980 | — |
| Saint Joseph Medical Center | Bloomington | Illinois | 61701 | — |
| Graham Hospital Association | Canton | Illinois | 61520 | — |
| Memorial Hospital | Carthage | Illinois | 62321 | — |
| Eureka Hospital | Eureka | Illinois | 61530 | — |
| Galesburg Clinic | Galesburg | Illinois | 61401 | — |
| Galesburg Cottage Hospital | Galesburg | Illinois | 61401 | — |
| Mason District Hospital | Havana | Illinois | 62644 | — |
| Mcdonough District Hospital | Macomb | Illinois | 61455 | — |
| Garneau, Stewart C MD (UIA Investigator) | Moline | Illinois | 61265 | — |
| Porubcin, Michael MD (UIA Investigator) | Moline | Illinois | 61265 | — |
| Sharis, Christine M MD (UIA Investigator) | Moline | Illinois | 61265 | — |
| Stoffel, Thomas J MD (UIA Investigator) | Moline | Illinois | 61265 | — |
| Holy Family Medical Center | Monmouth | Illinois | 61462 | — |
| Bromenn Regional Medical Center | Normal | Illinois | 61761 | — |
| Community Cancer Center Foundation | Normal | Illinois | 61761 | — |
| Illinois CancerCare-Ottawa Clinic | Ottawa | Illinois | 61350 | — |
| Ottawa Regional Hospital and Healthcare Center | Ottawa | Illinois | 61350 | — |
| Pekin Cancer Treatment Center | Pekin | Illinois | 61554 | — |
| Pekin Hospital | Pekin | Illinois | 61554 | — |
| Methodist Medical Center of Illinois | Peoria | Illinois | 61603 | — |
| Proctor Hospital | Peoria | Illinois | 61614 | — |
| Illinois CancerCare-Peoria | Peoria | Illinois | 61615 | — |
| Illinois Oncology Research Association CCOP | Peoria | Illinois | 61615 | — |
| OSF Saint Francis Medical Center | Peoria | Illinois | 61637 | — |
| Illinois Valley Hospital | Peru | Illinois | 61354 | — |
| Perry Memorial Hospital | Princeton | Illinois | 61356 | — |
| Saint Margaret's Hospital | Spring Valley | Illinois | 61362 | — |
| Saint Francis Hospital and Health Centers | Beech Grove | Indiana | 46107 | — |
| Elkhart General Hospital | Elkhart | Indiana | 46515 | — |
| Community Howard Regional Health | Kokomo | Indiana | 46904 | — |
| Indiana University Health La Porte Hospital | La Porte | Indiana | 46350 | — |
| Saint Joseph Regional Medical Center-Mishawaka | Mishawaka | Indiana | 46545-1470 | — |
| Reid Hospital and Health Care Services | Richmond | Indiana | 47374 | — |
| Memorial Hospital of South Bend | South Bend | Indiana | 46601 | — |
| Northern Indiana Cancer Research Consortium | South Bend | Indiana | 46601 | — |
| South Bend Clinic | South Bend | Indiana | 46617 | — |
| Constantinou, Costas L MD (UIA Investigator) | Bettendorf | Iowa | 52722 | — |
| Cedar Rapids Oncology Association | Cedar Rapids | Iowa | 52403 | — |
| Mercy Hospital | Cedar Rapids | Iowa | 52403 | — |
| Oncology Associates at Mercy Medical Center | Cedar Rapids | Iowa | 52403 | — |
| Medical Oncology and Hematology Associates-West Des Moines | Clive | Iowa | 50325 | — |
| Mercy Capitol | Des Moines | Iowa | 50307 | — |
| Iowa Methodist Medical Center | Des Moines | Iowa | 50309 | — |
| Iowa Oncology Research Association CCOP | Des Moines | Iowa | 50309 | — |
| Medical Oncology and Hematology Associates-Des Moines | Des Moines | Iowa | 50309 | — |
| Medical Oncology and Hematology Associates | Des Moines | Iowa | 50314 | — |
| Mercy Medical Center - Des Moines | Des Moines | Iowa | 50314 | — |
| Iowa Lutheran Hospital | Des Moines | Iowa | 50316 | — |
| Mercy Medical Center - North Iowa | Mason City | Iowa | 50401 | — |
| Siouxland Hematology Oncology Associates | Sioux City | Iowa | 51101 | — |
| Mercy Medical Center-Sioux City | Sioux City | Iowa | 51104 | — |
| Saint Luke's Regional Medical Center | Sioux City | Iowa | 51104 | — |
| Hospital District Sixth of Harper County | Anthony | Kansas | 67003 | — |
| Cancer Center of Kansas - Chanute | Chanute | Kansas | 66720 | — |
| Cancer Center of Kansas - Dodge City | Dodge City | Kansas | 67801 | — |
| Cancer Center of Kansas - El Dorado | El Dorado | Kansas | 67042 | — |
| Cancer Center of Kansas - Fort Scott | Fort Scott | Kansas | 66701 | — |
| Cancer Center of Kansas-Independence | Independence | Kansas | 67301 | — |
| Cancer Center of Kansas-Kingman | Kingman | Kansas | 67068 | — |
| Lawrence Memorial Hospital | Lawrence | Kansas | 66044 | — |
| Cancer Center of Kansas - Newton | Newton | Kansas | 67114 | — |
| Cancer Center of Kansas - Parsons | Parsons | Kansas | 67357 | — |
| Cancer Center of Kansas - Pratt | Pratt | Kansas | 67124 | — |
| Cancer Center of Kansas - Salina | Salina | Kansas | 67401 | — |
| Cancer Center of Kansas - Wellington | Wellington | Kansas | 67152 | — |
| Associates In Womens Health | Wichita | Kansas | 67208 | — |
| Cancer Center of Kansas-Wichita Medical Arts Tower | Wichita | Kansas | 67208 | — |
| Cancer Center of Kansas - Main Office | Wichita | Kansas | 67214 | — |
| Via Christi Regional Medical Center | Wichita | Kansas | 67214 | — |
| Wichita CCOP | Wichita | Kansas | 67214 | — |
| Cancer Center of Kansas - Winfield | Winfield | Kansas | 67156 | — |
| Bixby Medical Center | Adrian | Michigan | 49221 | — |
| Hickman Cancer Center | Adrian | Michigan | 49221 | — |
| Saint Joseph Mercy Hospital | Ann Arbor | Michigan | 48106-0995 | — |
| Michigan Cancer Research Consortium Community Clinical Oncology Program | Ann Arbor | Michigan | 48106 | — |
| Oakwood Hospital | Dearborn | Michigan | 48124 | — |
| Saint John Hospital and Medical Center | Detroit | Michigan | 48236 | — |
| Green Bay Oncology - Escanaba | Escanaba | Michigan | 49431 | — |
| Hurley Medical Center | Flint | Michigan | 48502 | — |
| Genesys Regional Medical Center-West Flint Campus | Flint | Michigan | 48532 | — |
| Green Bay Oncology - Iron Mountain | Iron Mountain | Michigan | 49801 | — |
| Allegiance Health | Jackson | Michigan | 49201 | — |
| Sparrow Hospital | Lansing | Michigan | 48912 | — |
| Saint Mary Mercy Hospital | Livonia | Michigan | 48154 | — |
| Community Cancer Center of Monroe | Monroe | Michigan | 48162 | — |
| Mercy Memorial Hospital | Monroe | Michigan | 48162 | — |
| Saint Joseph Mercy Oakland | Pontiac | Michigan | 48341-2985 | — |
| Saint Joseph Mercy Port Huron | Port Huron | Michigan | 48060 | — |
| Saint Mary's of Michigan | Saginaw | Michigan | 48601 | — |
| Lakeland Hospital | Saint Joseph | Michigan | 49085 | — |
| Saint John Macomb-Oakland Hospital | Warren | Michigan | 48093 | — |
| Sanford Clinic North-Bemidgi | Bemidji | Minnesota | 56601 | — |
| Fairview Ridges Hospital | Burnsville | Minnesota | 55337 | — |
| Mercy Hospital | Coon Rapids | Minnesota | 55433 | — |
| Essentia Health Duluth Clinic CCOP | Duluth | Minnesota | 55805 | — |
| Essentia Health Saint Mary's Medical Center | Duluth | Minnesota | 55805 | — |
| Miller-Dwan Hospital | Duluth | Minnesota | 55805 | — |
| Fairview-Southdale Hospital | Edina | Minnesota | 55435 | — |
| Unity Hospital | Fridley | Minnesota | 55432 | — |
| Hutchinson Area Health Care | Hutchinson | Minnesota | 55350 | — |
| Immanuel-Saint Joseph Hospital-Mayo Health System | Mankato | Minnesota | 56002 | — |
| Minnesota Oncology Hematology PA-Maplewood | Maplewood | Minnesota | 55109 | — |
| Saint John's Hospital - Healtheast | Maplewood | Minnesota | 55109 | — |
| Abbott-Northwestern Hospital | Minneapolis | Minnesota | 55407 | — |
| Virginia Piper Cancer Institute | Minneapolis | Minnesota | 55407 | — |
| Hennepin County Medical Center | Minneapolis | Minnesota | 55415 | — |
| North Memorial Medical Health Center | Robbinsdale | Minnesota | 55422 | — |
| Mayo Clinic | Rochester | Minnesota | 55905 | — |
| Metro-Minnesota CCOP | Saint Louis Park | Minnesota | 55416 | — |
| Park Nicollet Clinic - Saint Louis Park | Saint Louis Park | Minnesota | 55416 | — |
| Regions Hospital | Saint Paul | Minnesota | 55101 | — |
| United Hospital | Saint Paul | Minnesota | 55102 | — |
| Saint Francis Regional Medical Center | Shakopee | Minnesota | 55379 | — |
| Ridgeview Medical Center | Waconia | Minnesota | 55387 | — |
| Minnesota Oncology and Hematology PA-Woodbury | Woodbury | Minnesota | 55125 | — |
| Saint John's Hospital | Springfield | Missouri | 65804 | — |
| Missouri Baptist Medical Center | St Louis | Missouri | 63131 | — |
| Center for Cancer Care and Research | St Louis | Missouri | 63141 | — |
| Montana Cancer Consortium CCOP | Billings | Montana | 59101 | — |
| Northern Rockies Radiation Oncology Center | Billings | Montana | 59101 | — |
| Saint Vincent Healthcare | Billings | Montana | 59101 | — |
| Hematology-Oncology Centers of the Northern Rockies PC | Billings | Montana | 59102 | — |
| Billings Clinic | Billings | Montana | 59107-7000 | — |
| Bozeman Deaconess Cancer Center | Bozeman | Montana | 59715 | — |
| Saint James Community Hospital and Cancer Treatment Center | Butte | Montana | 59701 | — |
| Berdeaux, Donald MD (UIA Investigator) | Great Falls | Montana | 59405 | — |
| Great Falls Clinic | Great Falls | Montana | 59405 | — |
| Northern Montana Hospital | Havre | Montana | 59501 | — |
| Saint Peter's Community Hospital | Helena | Montana | 59601 | — |
| Glacier Oncology PLLC | Kalispell | Montana | 59901 | — |
| Kalispell Medical Oncology | Kalispell | Montana | 59901 | — |
| Kalispell Regional Medical Center | Kalispell | Montana | 59901 | — |
| Community Medical Hospital | Missoula | Montana | 59801 | — |
| Montana Cancer Specialists | Missoula | Montana | 59802 | — |
| Saint Patrick Hospital - Community Hospital | Missoula | Montana | 59802 | — |
| Guardian Oncology and Center for Wellness | Missoula | Montana | 59804 | — |
| Bismarck Cancer Center | Bismarck | North Dakota | 58501 | — |
| Mid Dakota Clinic | Bismarck | North Dakota | 58501 | — |
| Saint Alexius Medical Center | Bismarck | North Dakota | 58501 | — |
| Sanford Bismarck Medical Center | Bismarck | North Dakota | 58501 | — |
| Sanford Clinic North-Fargo | Fargo | North Dakota | 58122 | — |
| Sanford Medical Center-Fargo | Fargo | North Dakota | 58122 | — |
| Altru Cancer Center | Grand Forks | North Dakota | 58201 | — |
| Toledo Clinic Cancer Centers-Bowling Green | Bowling Green | Ohio | 43402 | — |
| North Coast Cancer Care-Clyde | Clyde | Ohio | 43410 | — |
| Grandview Hospital | Dayton | Ohio | 45405 | — |
| Good Samaritan Hospital - Dayton | Dayton | Ohio | 45406 | — |
| Miami Valley Hospital | Dayton | Ohio | 45409 | — |
| Samaritan North Health Center | Dayton | Ohio | 45415 | — |
| Dayton CCOP | Dayton | Ohio | 45420 | — |
| Hematology Oncology Center Incorporated | Elyria | Ohio | 44035 | — |
| Blanchard Valley Hospital | Findlay | Ohio | 45840 | — |
| Atrium Medical Center-Middletown Regional Hospital | Franklin | Ohio | 45005-1066 | — |
| Wayne Hospital | Greenville | Ohio | 45331 | — |
| Kettering Medical Center | Kettering | Ohio | 45429 | — |
| Lima Memorial Hospital | Lima | Ohio | 45804 | — |
| Toledo Clinic Cancer Centers-Maumee | Maumee | Ohio | 43537-1839 | — |
| Saint Luke's Hospital | Maumee | Ohio | 43537 | — |
| Toledo Radiation Oncology at Northwest Ohio Onocolgy Center | Maumee | Ohio | 43537 | — |
| Saint Charles Hospital | Oregon | Ohio | 43616 | — |
| Toledo Clinic Cancer Centers-Oregon | Oregon | Ohio | 43616 | — |
| North Coast Cancer Care | Sandusky | Ohio | 44870 | — |
| Flower Hospital | Sylvania | Ohio | 43560 | — |
| Mercy Hospital of Tiffin | Tiffin | Ohio | 44883 | — |
| The Toledo Hospital/Toledo Children's Hospital | Toledo | Ohio | 43606 | — |
| Saint Vincent Mercy Medical Center | Toledo | Ohio | 43608 | — |
| University of Toledo | Toledo | Ohio | 43614 | — |
| Toledo Community Hospital Oncology Program CCOP | Toledo | Ohio | 43617 | — |
| Mercy Cancer Center at Saint Anne Mercy Hospital | Toledo | Ohio | 43623 | — |
| Toledo Clinic Cancer Centers-Toledo | Toledo | Ohio | 43623 | — |
| Upper Valley Medical Center | Troy | Ohio | 45373 | — |
| Fulton County Health Center | Wauseon | Ohio | 43567 | — |
| Clinton Memorial Hospital | Wilmington | Ohio | 45177 | — |
| Greene Memorial Hospital | Xenia | Ohio | 45385 | — |
| Adventist Medical Center | Portland | Oregon | 97216 | — |
| Geisinger Medical Center | Danville | Pennsylvania | 17822-2001 | — |
| Geisinger Medical Center-Cancer Center Hazelton | Hazleton | Pennsylvania | 18201 | — |
| Geisinger Medical Group | State College | Pennsylvania | 16801 | — |
| Geisinger Wyoming Valley | Wilkes-Barre | Pennsylvania | 18711 | — |
| Fredericksburg Oncology Inc | Fredericksburg | Virginia | 22401 | — |
| Midelfort Clinic-Clairemont Campus | Eau Claire | Wisconsin | 54702 | — |
| Mayo Clinic Health System Eau Claire Hospital - Luther Campus | Eau Claire | Wisconsin | 54703 | — |
| Green Bay Oncology at Saint Vincent Hospital | Green Bay | Wisconsin | 54301-3526 | — |
| Saint Vincent Hospital | Green Bay | Wisconsin | 54301 | — |
| Green Bay Oncology Limited at Saint Mary's Hospital | Green Bay | Wisconsin | 54303 | — |
| Saint Mary's Hospital | Green Bay | Wisconsin | 54303 | — |
| Holy Family Memorial Hospital | Manitowoc | Wisconsin | 54221 | — |
| Bay Area Medical Center | Marinette | Wisconsin | 54143 | — |
| Green Bay Oncology - Oconto Falls | Oconto Falls | Wisconsin | 54154 | — |
| Green Bay Oncology - Sturgeon Bay | Sturgeon Bay | Wisconsin | 54235 | — |
| Welch Cancer Center | Sheridan | Wyoming | 82801 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00826540, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jan 19, 2026 · Synced Sep 25, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT00826540 live on ClinicalTrials.gov.