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Completed Phase 1Phase 2 Interventional

Efficacy, Tolerability and Safety of RKI983 (0.05% & 0.10%) vs Xalatan in Patients With POAG or Ocular Hypertension

ClinicalTrials.gov ID: NCT00846989

Public ClinicalTrials.gov record NCT00846989. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Jul 24, 2026, 5:15 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A 4-week Multi-center, Single-masked, Randomized, Latanoprost-controlled, Parallel Group Study to Assess the Efficacy, Tolerability and Safety of RKI983 (0.05% and 0.10%) Ophthalmic Solution Given Twice a Day Versus Once Daily Latanoprost 0.005%, in Patients With Primary Open Angle Glaucoma or Ocular Hypertension.

Study identification

NCT ID
NCT00846989
Recruitment status
Completed
Study type
Interventional
Phase
Phase 1, Phase 2
Lead sponsor
Novartis Pharmaceuticals
Industry
Enrollment
276 participants

Conditions and interventions

Interventions

  • RKI983A Drug
  • Latanoprost Drug

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
Male
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Dec 31, 2008
Primary completion
Mar 31, 2009
Completion
Mar 31, 2009
Last update posted
Dec 18, 2020

2009

United States locations

U.S. sites
29
U.S. states
18
U.S. cities
28
Facility City State ZIP Site status
Novartis Investigative Site Artesia California 90701
Novartis Investigative Site Inglewood California 90301
Novartis Investigative Site La Jolla California 92037
Novartis Investigative Site Poway California 92064
Novartis Investigative Site Stockton California 95207
Novartis Investigative Site Danbury Connecticut 06810
Novartis Investigative Site Atlanta Georgia 30342
Novartis Investigative Site Morrow Georgia 30260
Novartis Investigative Site Roswell Georgia 30076
Novartis Investigative Site Kaneohe Hawaii 96744
Novartis Investigative Site Topeka Kansas 66606
Novartis Investigative Site Louisville Kentucky 40217
Novartis Investigative Site Bossier City Louisiana 71111
Novartis Investigative Site Cambridge Massachusetts 02142
Novartis Investigative Site Springfield Missouri 65804
Novartis Investigative Site Omaha Nebraska 68131
Novartis Investigative Site Las Vegas Nevada 89148
Novartis Investigative Site Bethpage New York 11714
Novartis Investigative Site Lynbrook New York 11563
Novartis Investigative Site Rochester New York 14618
Novartis Investigative Site Charlotte North Carolina 28204
Novartis Investigative Site Charlotte North Carolina 28210
Novartis Investigative Site Tulsa Oklahoma 74104
Novartis Investigative Site Mt. Pleasant South Carolina 29464
Novartis Investigative Site Memphis Tennessee 38119
Novartis Investigative Site El Paso Texas 79904
Novartis Investigative Site Houston Texas 77030
Novartis Investigative Site San Antonio Texas 78229
Novartis Investigative Site Spokane Washington 99202

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00846989, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Dec 18, 2020 · Synced Jul 24, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT00846989 live on ClinicalTrials.gov.

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