ClinicalTrials.gov record
Treatment With Pazopanib for Neoadjuvant Breast Cancer
ClinicalTrials.gov ID: NCT00849472
Public ClinicalTrials.gov record NCT00849472. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase II Clinical Trial of Four Cycles of Doxorubicin and Cyclophosphamide Followed by Weekly Paclitaxel Given Concurrently With Pazopanib as Neoadjuvant Therapy Followed by Postoperative Pazopanib for Women With Locally Advanced Breast Cancer
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to determine whether the treatment of a doxorubicin in combination with cyclophosphamide followed by a combination of pazopanib in combination with paclitaxel prior to surgery results in a pathological complete response in females with breast cancer.
Study identification
- NCT ID
- NCT00849472
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 101 participants
Conditions and interventions
Conditions
Interventions
- doxorubicin + cyclophosphamide Drug
- paclitaxel + pazopanib Drug
- surgery Procedure
- pazopanib monotherapy Drug
Drug · Procedure
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- Female
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jun 30, 2009
- Primary completion
- Nov 30, 2011
- Completion
- Mar 31, 2013
- Last update posted
- Mar 3, 2014
2009 – 2013
United States locations
- U.S. sites
- 137
- U.S. states
- 21
- U.S. cities
- 100
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| GSK Investigational Site | Decatur | Alabama | 35601 | — |
| GSK Investigational Site | Huntsville | Alabama | 35801 | — |
| GSK Investigational Site | Huntsville | Alabama | 35805 | — |
| GSK Investigational Site | Antioch | California | 94531 | — |
| GSK Investigational Site | Fremont | California | 94538 | — |
| GSK Investigational Site | Hayward | California | 94545 | — |
| GSK Investigational Site | Oakland | California | 94611 | — |
| GSK Investigational Site | Redwood City | California | 94063 | — |
| GSK Investigational Site | Richmond | California | 94801 | — |
| GSK Investigational Site | Roseville | California | 95661 | — |
| GSK Investigational Site | Sacramento | California | 95823 | — |
| GSK Investigational Site | Sacramento | California | 95825 | — |
| GSK Investigational Site | San Francisco | California | 94115 | — |
| GSK Investigational Site | San Jose | California | 95119-1110 | — |
| GSK Investigational Site | San Rafael | California | 94903 | — |
| GSK Investigational Site | Santa Clara | California | 95051 | — |
| GSK Investigational Site | Santa Rosa | California | 95403-2192 | — |
| GSK Investigational Site | South San Francisco | California | 94080 | — |
| GSK Investigational Site | Stockton | California | 95210 | — |
| GSK Investigational Site | Vacaville | California | 95688 | — |
| GSK Investigational Site | Vallejo | California | 94589 | — |
| GSK Investigational Site | Walnut Creek | California | 94596 | — |
| GSK Investigational Site | Colorado Springs | Colorado | 80907 | — |
| GSK Investigational Site | Denver | Colorado | 80205 | — |
| GSK Investigational Site | Denver | Colorado | 80210 | — |
| GSK Investigational Site | Denver | Colorado | 80218 | — |
| GSK Investigational Site | Denver | Colorado | 80224 | — |
| GSK Investigational Site | Denver | Colorado | 80244 | — |
| GSK Investigational Site | Englewood | Colorado | 80113 | — |
| GSK Investigational Site | Greeley | Colorado | 80631 | — |
| GSK Investigational Site | Lafayette | Colorado | 80026 | — |
| GSK Investigational Site | Wheat Ridge | Colorado | 80033 | — |
| GSK Investigational Site | Wheat Ridge | Colorado | 80333 | — |
| GSK Investigational Site | Fernandina Beach | Florida | 32034 | — |
| GSK Investigational Site | Gainesville | Florida | 32610 | — |
| GSK Investigational Site | Jacksonville | Florida | 32205 | — |
| GSK Investigational Site | Jacksonville | Florida | 32207 | — |
| GSK Investigational Site | Jacksonville | Florida | 32256 | — |
| GSK Investigational Site | Jacksonville | Florida | 32258 | — |
| GSK Investigational Site | Orange Park | Florida | 32073 | — |
| GSK Investigational Site | Savannah | Georgia | 31404 | — |
| GSK Investigational Site | Savannah | Georgia | 31405 | — |
| GSK Investigational Site | Honolulu | Hawaii | 96819 | — |
| GSK Investigational Site | Iowa City | Iowa | 52242 | — |
| GSK Investigational Site | Jeffersonville | Kentucky | 47130 | — |
| GSK Investigational Site | Louisville | Kentucky | 40202 | — |
| GSK Investigational Site | Louisville | Kentucky | 40207 | — |
| GSK Investigational Site | Louisville | Kentucky | 40217 | — |
| GSK Investigational Site | Louisville | Kentucky | — | — |
| GSK Investigational Site | Baltimore | Maryland | 21237 | — |
| GSK Investigational Site | Ann Arbor | Michigan | 48106 | — |
| GSK Investigational Site | Battle Creek | Michigan | 49016 | — |
| GSK Investigational Site | Brighton | Michigan | 48114 | — |
| GSK Investigational Site | Byron Center | Michigan | 49519 | — |
| GSK Investigational Site | Dearborn | Michigan | 48123 | — |
| GSK Investigational Site | Dearborn | Michigan | 48162 | — |
| GSK Investigational Site | Detroit | Michigan | 48236 | — |
| GSK Investigational Site | Flint | Michigan | 48502 | — |
| GSK Investigational Site | Flint | Michigan | 48503 | — |
| GSK Investigational Site | Flint | Michigan | 48532 | — |
| GSK Investigational Site | Grand Rapids | Michigan | 49503 | — |
| GSK Investigational Site | Grosse Point Woods | Michigan | 19229 | — |
| GSK Investigational Site | Lansing | Michigan | 48910 | — |
| GSK Investigational Site | Lansing | Michigan | 48912 | — |
| GSK Investigational Site | Livonia | Michigan | 48154 | — |
| GSK Investigational Site | Mount Clemens | Michigan | 48043 | — |
| GSK Investigational Site | Muskegon | Michigan | 49444 | — |
| GSK Investigational Site | Port Huron | Michigan | 48060 | — |
| GSK Investigational Site | Saginaw | Michigan | 48601 | — |
| GSK Investigational Site | Traverse City | Michigan | 49684 | — |
| GSK Investigational Site | Warren | Michigan | 48093 | — |
| GSK Investigational Site | Brunsville | Minnesota | 55337 | — |
| GSK Investigational Site | Edina | Minnesota | 55435 | — |
| GSK Investigational Site | Fridley | Minnesota | 55432 | — |
| GSK Investigational Site | Maplewood | Minnesota | 55109 | — |
| GSK Investigational Site | Minneapolis | Minnesota | 55433 | — |
| GSK Investigational Site | Minneapolis | Minnesota | 55454 | — |
| GSK Investigational Site | Saint Louis Park | Minnesota | 55416 | — |
| GSK Investigational Site | Saint Paul | Minnesota | 55101 | — |
| GSK Investigational Site | Saint Paul | Minnesota | 55102 | — |
| GSK Investigational Site | Woodbury | Minnesota | 55125 | — |
| GSK Investigational Site | New Brunswick | New Jersey | 08901 | — |
| GSK Investigational Site | Stony Brook | New York | 11794 | — |
| GSK Investigational Site | Charlotte | North Carolina | 28203 | — |
| GSK Investigational Site | Charlotte | North Carolina | 28204 | — |
| GSK Investigational Site | Charlotte | North Carolina | 28210 | — |
| GSK Investigational Site | Charlotte | North Carolina | 28211 | — |
| GSK Investigational Site | Charlotte | North Carolina | 28262 | — |
| GSK Investigational Site | Clinton | North Carolina | 28328 | — |
| GSK Investigational Site | Goldsboro | North Carolina | 27534 | — |
| GSK Investigational Site | Greenville | North Carolina | 27834 | — |
| GSK Investigational Site | Wilson | North Carolina | 27893 | — |
| GSK Investigational Site | Winston-Salem | North Carolina | 27014 | — |
| GSK Investigational Site | Winston-Salem | North Carolina | 27157 | — |
| GSK Investigational Site | Canton | Ohio | 44710 | — |
| GSK Investigational Site | Chargrin | Ohio | 44122 | — |
| GSK Investigational Site | Clevand | Ohio | 44106 | — |
| GSK Investigational Site | Dayton | Ohio | 45331 | — |
| GSK Investigational Site | Dayton | Ohio | 45415 | — |
| GSK Investigational Site | Dayton | Ohio | 45429 | — |
| GSK Investigational Site | Kettering | Ohio | 45409 | — |
| GSK Investigational Site | Kettering | Ohio | 45429 | — |
| GSK Investigational Site | Lebanon | Ohio | 45036 | — |
| GSK Investigational Site | Mentor | Ohio | 44060 | — |
| GSK Investigational Site | Middletown | Ohio | 45042 | — |
| GSK Investigational Site | Westlake | Ohio | 44145 | — |
| GSK Investigational Site | Wilminton | Ohio | 45042 | — |
| GSK Investigational Site | Xenia | Ohio | 45385 | — |
| GSK Investigational Site | Portland | Oregon | 97213 | — |
| GSK Investigational Site | Portland | Oregon | 97225 | — |
| GSK Investigational Site | Portland | Oregon | — | — |
| GSK Investigational Site | Ephrata | Pennsylvania | 17522 | — |
| GSK Investigational Site | Greensburg | Pennsylvania | 15601 | — |
| GSK Investigational Site | Philadelphia | Pennsylvania | 19107 | — |
| GSK Investigational Site | Philadelphia | Pennsylvania | 19115 | — |
| GSK Investigational Site | Philadelphia | Pennsylvania | 19141 | — |
| GSK Investigational Site | Pittsburgh | Pennsylvania | 15212 | — |
| GSK Investigational Site | Pittsburgh | Pennsylvania | 15213 | — |
| GSK Investigational Site | Pittsburgh | Pennsylvania | 15215 | — |
| GSK Investigational Site | Pittsburgh | Pennsylvania | 15232 | — |
| GSK Investigational Site | Pittsburgh | Pennsylvania | 15237 | — |
| GSK Investigational Site | West Reading | Pennsylvania | 19611 | — |
| GSK Investigational Site | Lubbock | Texas | 79410 | — |
| GSK Investigational Site | Richmond | Virginia | 23235 | — |
| GSK Investigational Site | Richmond | Virginia | 23298 | — |
| GSK Investigational Site | Seattle | Washington | 98101 | — |
| GSK Investigational Site | Vancouver | Washington | 98668 | — |
| GSK Investigational Site | Vancover | Washington | 98684 | — |
| GSK Investigational Site | Chippewa Falls | Wisconsin | 54729 | — |
| GSK Investigational Site | Eau Claire | Wisconsin | 54701 | — |
| GSK Investigational Site | Marshfield | Wisconsin | 54449 | — |
| GSK Investigational Site | Minocqua | Wisconsin | 54548 | — |
| GSK Investigational Site | Rhinelander | Wisconsin | 54501 | — |
| GSK Investigational Site | Rice Lake | Wisconsin | 54868 | — |
| GSK Investigational Site | Stevens Point | Wisconsin | 54481 | — |
| GSK Investigational Site | Weston | Wisconsin | 54476 | — |
| GSK Investigational Site | Wisconsin Rapids | Wisconsin | 54494 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 6 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00849472, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Mar 3, 2014 · Synced Sep 11, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT00849472 live on ClinicalTrials.gov.