Live Zoster Vaccine in HIV-Infected Adults on Antiretroviral Therapy
Public ClinicalTrials.gov record NCT00851786. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase II, Randomized, Double-Blind, Placebo-Controlled Clinical Trial to Evaluate the Safety, Tolerability, and Immunogenicity of ZOSTAVAX® (Zoster Vaccine Live) in Human Immunodeficiency Virus (HIV)-1-Infected Adults on Potent Combination ART With Conserved Immune Function
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
Herpes zoster, or shingles, is the result of a viral infection that causes a painful skin rash, usually in older people or people with suppressed immune systems like those infected with HIV. The ZOSTAVAX vaccine has been shown to reduce the number of infections and symptoms of herpes zoster infection in people over the age of 60. The purpose of this study is to evaluate the safety, tolerability, and immunogenicity of two doses of ZOSTAVAX in HIV-1-infected adults with conserved immune function (Cd4+ T cell counts \>=200 cells/uL) virologically suppressed on potent combination antiretroviral therapy (ART).
Study identification
- NCT ID
- NCT00851786
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 395 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Apr 29, 2009 (Actual)
- Primary completion
- Sep 22, 2011 (Actual)
- Completion
- Jan 3, 2012 (Actual)
- Last update posted
- Nov 4, 2021
2009 – 2012
United States locations
- U.S. sites
- 43
- U.S. states
- 20
- U.S. cities
- 33
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Alabama Therapeutics CRS | Birmingham | Alabama | 35294-2050 | — |
| University of Southern California CRS | Los Angeles | California | 90033 | — |
| UCLA CARE Center CRS | Los Angeles | California | 90035 | — |
| Stanford CRS | Palo Alto | California | 94304-5350 | — |
| Ucsd, Avrc Crs | San Diego | California | 92103 | — |
| Ucsf Aids Crs | San Francisco | California | 94110 | — |
| Harbor-UCLA Med. Ctr. CRS | Torrance | California | 90502 | — |
| University of Colorado Hospital CRS | Aurora | Colorado | 80045 | — |
| Denver Public Health CRS | Denver | Colorado | 80204 | — |
| Georgetown University CRS (GU CRS) | Washington D.C. | District of Columbia | 20007 | — |
| Univ. of Miami AIDS CRS | Miami | Florida | 33136 | — |
| The Ponce de Leon Center CRS | Atlanta | Georgia | 30308-2012 | — |
| Northwestern University CRS | Chicago | Illinois | 60611 | — |
| Rush Univ. Med. Ctr. ACTG CRS | Chicago | Illinois | 60612 | — |
| IHV Baltimore Treatment CRS | Baltimore | Maryland | 21201 | — |
| Johns Hopkins Adult AIDS CRS | Baltimore | Maryland | 21287 | — |
| Massachusetts General Hospital ACTG CRS | Boston | Massachusetts | 02114 | — |
| Brigham and Women's Hosp. ACTG CRS | Boston | Massachusetts | 02115 | — |
| Bmc Actg Crs | Boston | Massachusetts | 02118 | — |
| Beth Israel Deaconess Med. Ctr., ACTG CRS | Boston | Massachusetts | 02215 | — |
| Henry Ford Hosp. CRS | Detroit | Michigan | 48202 | — |
| Washington U CRS | St Louis | Missouri | 63110 | — |
| Cooper Univ. Hosp. CRS | Camden | New Jersey | 08103 | — |
| New Jersey Medical School- Adult Clinical Research Ctr. CRS | Newark | New Jersey | 07103 | — |
| Cornell CRS | New York | New York | 10010 | — |
| NY Univ. HIV/AIDS CRS | New York | New York | 10016 | — |
| HIV Prevention & Treatment CRS | New York | New York | 10032 | — |
| Univ. of Rochester ACTG CRS | Rochester | New York | 14642 | — |
| Bronx-Lebanon Hosp. Ctr. CRS | The Bronx | New York | 10457 | — |
| Chapel Hill CRS | Chapel Hill | North Carolina | 27599 | — |
| Duke Univ. Med. Ctr. Adult CRS | Durham | North Carolina | 27710 | — |
| Greensboro CRS | Greensboro | North Carolina | 27401 | — |
| Univ. of Cincinnati CRS | Cincinnati | Ohio | 45267-0405 | — |
| Case CRS | Cleveland | Ohio | 44106 | — |
| MetroHealth CRS | Cleveland | Ohio | 44109 | — |
| The Ohio State University Medical Center | Columbus | Ohio | 43210 | — |
| The Research & Education Group-Portland CRS | Portland | Oregon | 97210 | — |
| Hosp. of the Univ. of Pennsylvania CRS | Philadelphia | Pennsylvania | 19104 | — |
| Thomas Jefferson Univ. Med. Ctr. CRS | Philadelphia | Pennsylvania | 19107 | — |
| Pitt CRS | Pittsburgh | Pennsylvania | 15213-2582 | — |
| The Miriam Hosp. ACTG CRS | Providence | Rhode Island | 02906 | — |
| Vanderbilt Therapeutics CRS | Nashville | Tennessee | 37204 | — |
| University of Washington AIDS CRS | Seattle | Washington | 98104 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00851786, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Nov 4, 2021 · Synced Oct 25, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00851786 live on ClinicalTrials.gov.