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Terminated Phase 2 Interventional Results available

A Research Study To Assess The Effectiveness And Safety Of Different Doses Of Oral PF-00489791 In The Treatment Of Adult Patients With Pulmonary Arterial Hypertension

ClinicalTrials.gov ID: NCT00853112

Public ClinicalTrials.gov record NCT00853112. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 3, 2026, 1:33 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 2a, Randomized, Double Blind, Placebo-controlled, Parallel Group Study Investigating The Dose-response Of Pf-00489791 On Acute Hemodynamics In Subjects With Idiopathic And Familial Pulmonary Arterial Hypertension

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

Study will assess PF-00489791 efficacy and safety in Pulmonary Arterial Hypertension (PAH)

Study identification

NCT ID
NCT00853112
Recruitment status
Terminated
Study type
Interventional
Phase
Phase 2
Lead sponsor
Pfizer
Industry
Enrollment
48 participants

Conditions and interventions

Interventions

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Mar 31, 2009
Primary completion
Jun 30, 2010
Completion
Jun 30, 2010
Last update posted
Oct 23, 2017

2009 – 2010

United States locations

U.S. sites
8
U.S. states
5
U.S. cities
5
Facility City State ZIP Site status
Pulmonary Associates, PA Phoenix Arizona 85006
John C. Lincoln Hospital, North Mountain Phoenix Arizona 85020
Pulmonary Associates, PA Phoenix Arizona 85020
Shands at University of Florida Gainesville Florida 32610
Creighton University Medical Center Omaha Nebraska 68131
Allegheny General Hospital Pittsburgh Pennsylvania 15212
UT Southwestern Medical Center - Department of Internal Medicine Pulmonary Dallas Texas 75390
UT Southwestern St. Paul Hospital Dallas Texas 75390

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 17 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00853112, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Oct 23, 2017 · Synced Sep 3, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT00853112 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →