Efficacy and Safety Study of Desmoteplase to Treat Acute Ischemic Stroke (DIAS-4)
Public ClinicalTrials.gov record NCT00856661. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomised, Double-Blind, Parallel-Group Placebo-Controlled Phase III Study to Evaluate the Efficacy and Safety of Desmoteplase in Subjects With Acute Ischemic Stroke
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of the study is to determine whether desmoteplase is effective and safe in the treatment of patients with acute ischaemic stroke when given within 3 to 9 hours from onset of stroke symptoms.
Study identification
- NCT ID
- NCT00856661
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 270 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 85 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Mar 31, 2009
- Primary completion
- Sep 30, 2014
- Completion
- Not listed
- Last update posted
- Mar 15, 2017
Started 2009
United States locations
- U.S. sites
- 81
- U.S. states
- 28
- U.S. cities
- 69
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| US053 | Phoenix | Arizona | 85054 | — |
| US081 | Castro Valley | California | 94546 | — |
| US089 | La Jolla | California | 92037 | — |
| US043 | Loma Linda | California | 92354 | — |
| US008 | Los Angeles | California | 90024-1777 | — |
| US020 | Palo Alto | California | 94304 | — |
| US050 | Pasadena | California | 91105 | — |
| US098 | Santa Barbara | California | 93105 | — |
| US051 | Thousand Oaks | California | 91360 | — |
| US068 | Englewood | Colorado | 80113 | — |
| US063 | Fairfield | Connecticut | 06824 | — |
| US104 | New Haven | Connecticut | 06510 | — |
| US049 | Pensacola | Florida | 32504 | — |
| US109 | Atlanta | Georgia | 30303 | — |
| US042 | Augusta | Georgia | 30912 | — |
| US052 | Columbus | Georgia | 31902 | — |
| US080 | Decatur | Georgia | 30033 | — |
| US040 | Lawrenceville | Georgia | 30045 | — |
| US067 | Macon | Georgia | 31201 | — |
| US085 | Savannah | Georgia | 31405 | — |
| US086 | Savannah | Georgia | 31419 | — |
| US093 | Chicago | Illinois | 60611 | — |
| US101 | Chicago | Illinois | 60612 | — |
| US044 | Chicago | Illinois | 60622 | — |
| US074 | Evanston | Illinois | 60201 | — |
| US073 | Glenview | Illinois | 60026 | — |
| US091 | Maywood | Illinois | 60153 | — |
| US088 | Oak Lawn | Illinois | 60453 | — |
| US016 | Indianapolis | Indiana | 46260 | — |
| US072 | Des Moines | Iowa | 50314-2611 | — |
| US061 | New Orleans | Louisiana | 70112 | — |
| US108 | New Orleans | Louisiana | 70121 | — |
| US064 | Shreveport | Louisiana | 71130-3932 | — |
| US014 | Baltimore | Maryland | 21231 | — |
| US039 | Boston | Massachusetts | 02114 | — |
| US003 | Boston | Massachusetts | 02118 | — |
| US017 | Worcester | Massachusetts | 01605 | — |
| US066 | Detroit | Michigan | 48201 | — |
| US096 | Detroit | Michigan | 48202 | — |
| US083 | Detroit | Michigan | 48236 | — |
| US060 | Grand Blanc | Michigan | 48439 | — |
| US078 | Grand Rapids | Michigan | 49503 | — |
| US103 | Kalamazoo | Michigan | 49007 | — |
| US056 | Petoskey | Michigan | 49770 | — |
| US113 | Royal Oak | Michigan | 48073 | — |
| US076 | Southfield | Michigan | 48075 | — |
| US082 | Southfield | Michigan | 48075 | — |
| US079 | Troy | Michigan | 48085 | — |
| US059 | Gulfport | Mississippi | 39502 | — |
| US048 | Springfield | Missouri | 65807 | — |
| US077 | Lebanon | New Hampshire | 03756 | — |
| US055 | Edison | New Jersey | 08818 | — |
| US115 | Neptune City | New Jersey | 07753 | — |
| US100 | Ridgewood | New Jersey | 07450 | — |
| US075 | Albany | New York | 12208 | — |
| US102 | Brooklyn | New York | 11220 | — |
| US012 | Buffalo | New York | 14203 | — |
| US026 | Stony Brook | New York | 11794-8121 | — |
| US037 | Greensboro | North Carolina | 27401 | — |
| US069 | Winston-Salem | North Carolina | 27157 | — |
| US038 | Cleveland | Ohio | 44109 | — |
| US001 | Columbus | Ohio | 43210 | — |
| US062 | Columbus | Ohio | 43214 | — |
| US046 | Toledo | Ohio | 43614 | — |
| US095 | Springfield | Oregon | 97477 | — |
| US070 | Allentown | Pennsylvania | 18103 | — |
| US023 | Philadelphia | Pennsylvania | 19141 | — |
| US099 | Pittsburgh | Pennsylvania | 15212 | — |
| US084 | Pittsburgh | Pennsylvania | 15213 | — |
| US092 | Providence | Rhode Island | 02903 | — |
| US087 | Warwick | Rhode Island | 02886 | — |
| US057 | Columbia | South Carolina | 29203 | — |
| US019 | Chattanooga | Tennessee | 37403 | — |
| US058 | Nashville | Tennessee | 37205 | — |
| US021 | Houston | Texas | 77030 | — |
| US031 | Houston | Texas | 77030 | — |
| US112 | Houston | Texas | 77030 | — |
| US047 | Richmond | Virginia | 23298 | — |
| US006 | Winchester | Virginia | 22601 | — |
| US011 | Madison | Wisconsin | 53792 | — |
| US097 | Milwaukee | Wisconsin | 53226 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 71 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00856661, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Mar 15, 2017 · Synced Sep 26, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT00856661 live on ClinicalTrials.gov.