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Completed Phase 3 Interventional

First Line Hepato Cellular Carcinoma (HCC)

ClinicalTrials.gov ID: NCT00858871

Public ClinicalTrials.gov record NCT00858871. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 3, 2026, 12:51 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Randomized, Double-blind, Multi-center Phase III Study of Brivanib Versus Sorafenib as First-line Treatment in Patients With Advanced Hepatocellular Carcinoma

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The purpose of this study is to compare the overall survival of brivanib versus sorafenib in subjects with advanced HCC who have not received prior systemic therapy.

Study identification

NCT ID
NCT00858871
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Lead sponsor
Bristol-Myers Squibb
Industry
Enrollment
1,714 participants

Conditions and interventions

Interventions

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Apr 30, 2009
Primary completion
May 31, 2012
Completion
Aug 31, 2013
Last update posted
Oct 16, 2016

2009 – 2013

United States locations

U.S. sites
12
U.S. states
10
U.S. cities
12
Facility City State ZIP Site status
Mayo Clinic Arizona Scottsdale Arizona 85259
Univ Of Ark For Med Sci Little Rock Arkansas 72205
Agajanian Institute Of Hematology And Oncology Downey California 90241
Sharp Clinical Oncology Research San Diego California 92123
Va Ct Healthcare System West Haven Connecticut 06516
Medical Specialists Of Palm Beaches Lake Worth Florida 33467
James Graham Brown Cancer Center Louisville Kentucky 40202
3912 Taubman Center Ann Arbor Michigan 48109
Karmanos Cancer Institute Detroit Michigan 48201
Thomas Jefferson Univ. Philadelphia Pennsylvania 19107
Mcguire Dvamc Richmond Virginia 23249
University Of Wisconsin Madison Wisconsin 53792

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 161 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00858871, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Oct 16, 2016 · Synced Sep 3, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT00858871 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →