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Completed Phase 2 Interventional

Randomized, Controlled Study Evaluating CERE-110 in Subjects With Mild to Moderate Alzheimer's Disease

ClinicalTrials.gov ID: NCT00876863

Public ClinicalTrials.gov record NCT00876863. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced May 6, 2026, 8:42 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Double-Blind, Placebo-Controlled (Sham Surgery), Randomized, Multicenter Study Evaluating CERE-110 Gene Delivery in Subjects With Mild to Moderate Alzheimer's Disease

Study identification

NCT ID
NCT00876863
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
Sangamo Therapeutics
Industry
Enrollment
49 participants

Conditions and interventions

Interventions

  • CERE-110: Adeno-Associated Virus injection Surgery Drug
  • Placebo Surgery Procedure

Drug · Procedure

Eligibility (public fields only)

Age range
55 Years to 80 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Oct 31, 2008
Primary completion
Aug 12, 2015
Completion
Aug 12, 2015
Last update posted
Dec 20, 2020

2008 – 2015

United States locations

U.S. sites
10
U.S. states
9
U.S. cities
10
Facility City State ZIP Site status
University of Alabama Birmingham Alabama 35294
University of California, Los Angeles Los Angeles California 90095
University of California, San Diego San Diego California 92037
Georgetown University Washington D.C. District of Columbia 20007
Emory University Atlanta Georgia 30325
Mount Sinai School of Medicine New York New York 10029
Duke University Durham North Carolina 27710
Case Western Reserve University Cleveland Ohio 44120
Medical University of South Carolina North Charleston South Carolina 29406
University of Utah Salt Lake City Utah 84108

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00876863, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Dec 20, 2020 · Synced May 6, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT00876863 live on ClinicalTrials.gov.

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