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Completed Phase 4 Interventional Results available

Safety and Efficacy of Vyvanse in Adults With Attention-Deficit/Hyperactivity Disorder

ClinicalTrials.gov ID: NCT00877487

Public ClinicalTrials.gov record NCT00877487. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 5, 2026, 1:17 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 4, Double-Blind, Multi-Center, Placebo-Controlled, Randomized Withdrawal, Safety and Efficacy Study of SPD489 in Adults Aged 18-55 With Attention-Deficit/Hyperactivity Disorder (ADHD)

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The primary objective of this study is to evaluate the maintenance of efficacy, as measured by Adult ADHD Rating Scale with Prompts (Adult ADHD-RS with prompts) and Clinical Global Impression - Severity (CGI-S) scores, through a randomized withdrawal design when subjects with ADHD have been on stable treatment with commercial SPD489 for a minimum of 6 months and are maintained on their screening dose of commercial SPD489.

Study identification

NCT ID
NCT00877487
Recruitment status
Completed
Study type
Interventional
Phase
Phase 4
Lead sponsor
Shire
Industry
Enrollment
123 participants

Conditions and interventions

Eligibility (public fields only)

Age range
18 Years to 55 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Apr 29, 2009
Primary completion
Jul 7, 2010
Completion
Jul 7, 2010
Last update posted
Jun 21, 2021

2009 – 2010

United States locations

U.S. sites
55
U.S. states
29
U.S. cities
54
Facility City State ZIP Site status
Clinical Study Centers, LLC Little Rock Arkansas 72205
Valley Clinical Research, Inc. El Centro California 92243
Peninsula Research Associates, Inc Rolling Hills Estates California 90274
PCSD Feighner Research San Diego California 92108
Elite Clinical Trials, Inc. Wildomar California 92595
Colorado Clinica Trials, Inc. Highlands Ranch Colorado 80130
Florida Clinical Research Center Bradenton Florida 34208
Gulfcoast Clinical Research Center Fort Myers Florida 33912
Clinical Neuroscience Solutions Inc Jacksonville Florida 32216
Fidelity Clinical Research, Inc. Lauderhill Florida 33319
CNS Healthcare Orlando Florida 32806
Miami Research Associates South Miami Florida 33143
Janus Center for Psychiatric Research West Palm Beach Florida 33407
Atlanta Center for Medical Research Atlanta Georgia 30308
Northwest Behavioral Research Center Roswell Georgia 30076
Joliet Center for Clinical Research Joliet Illinois 60435
Capstone Clinical Research Libertyville Illinois 60048
CIENTIFICA, Inc Newton Kansas 67114
Psychiatric Associates Overland Park Kansas 66211
Vince and Associates Clinical Research Overland Park Kansas 66212
Clinical Trial Technology Inc. Prairie Village Kansas 66206
Pedia Research LLC Owensboro Kentucky 42301
Four Rivers Clinical Research Paducah Kentucky 42003
Not listed Rockville Maryland 20852
Rochester Center for Behavioral Medicine Rochester Hills Michigan 48307
The Behavioral Medicine Clinic of NW Michigan Traverse City Michigan 49686
Behavioral Medical Center-Troy Troy Michigan 48083
Midwest Research Group/ St. Charles Psychiatric Associates Saint Charles Missouri 63301
Premier Psychiatric Research Institute, LLC Lincoln Nebraska 68510
Center for Psychiatry and Behavioral Medicine Inc. Las Vegas Nevada 89128
Center for Emotional Fitness Cherry Hill New Jersey 08002
Global Medical Institutes, LLC. Princeton Medical Institute Princeton New Jersey 08540
Richmond Behavioral Associates Staten Island New York 10312
Richard H. Weisler, MD, PA & Associates Raleigh North Carolina 27609
Prarie St. Johns/ Odyssey Research Fargo North Dakota 58104
UHCMC/ Discovery and Wellness Center for Children Cleveland Ohio 44106
IPS Research Company Oklahoma City Oklahoma 73703
Calcagno Pediatrics Gresham Oregon 97030
Introspect of Buxmont, Ltd. Colmar Pennsylvania 18915
Youth and Family Research Program Pittsburgh Pennsylvania 15213
Carolina Clinical Trials, Inc. Charleston South Carolina 29407
CNS Healthcare Memphis Tennessee 38119
FutureSearch Trials Austin Texas 78756
FutureSearch Trials of Dallas, LP Dallas Texas 75231
Bayou City Reserch, Ltd. Houston Texas 77007
Westex Clinical Investigators Lubbock Texas 79423
Cerebral Research, LLC San Antonio Texas 78247
Aspen Clinical Research Orem Utah 84058
Vermont Clinical Study Center Burlington Vermont 05401
Neuropsychiatric Associates Woodstock Vermont 05091
Psychiatric Alliance of the Blue Ridge Charlottesville Virginia 22903
Dominion Clinical Research Midlothian Virginia 23112
Northwest Clinical Research Center Bellevue Washington 98004
Eastside Therapeutic Resource Kirkland Washington 98033
Dean Foundation Middleton Wisconsin 53562

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00877487, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jun 21, 2021 · Synced Sep 5, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT00877487 live on ClinicalTrials.gov.

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