ClinicalTrials.gov record
Study Evaluating The Effects Of Neratinib After Adjuvant Trastuzumab In Women With Early Stage Breast Cancer
ClinicalTrials.gov ID: NCT00878709
Public ClinicalTrials.gov record NCT00878709. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Double-Blind, Placebo-Controlled Trial Of Neratinib (HKI-272) After Trastuzumab In Women With Early-Stage HER-2/Neu Overexpressed/Amplified Breast Cancer
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to investigate whether neratinib can further reduce the risk of recurrence from previously diagnosed HER-2 positive breast cancer after adjuvant treatment with trastuzumab.
Study identification
- NCT ID
- NCT00878709
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 2,840 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- Female
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jul 9, 2009 (Actual)
- Primary completion
- Aug 21, 2014 (Actual)
- Completion
- Oct 4, 2019 (Actual)
- Last update posted
- Jun 11, 2021
2009 – 2019
United States locations
- U.S. sites
- 185
- U.S. states
- 42
- U.S. cities
- 150
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Anniston Oncology | Anniston | Alabama | 36207 | — |
| Birmingham Hematology and Oncology Associates, LLC | Birmingham | Alabama | 35205 | — |
| Arizona Oncology Associates, PC - HAL | Phoenix | Arizona | 85016 | — |
| Arizona Oncology Associates, PC - NAHOA | Sedona | Arizona | 86336 | — |
| Arizona Oncology Associates | Tucson | Arizona | 85704-7891 | — |
| Arizona Cancer Center | Tucson | Arizona | 85724 | — |
| Northeast Arkansas Clinic | Jonesboro | Arkansas | 72401 | — |
| Cedars-Sinai Medical Group | Beverly Hills | California | 90211 | — |
| Ronald Yanagihara, M.D. | Gilroy | California | 95020 | — |
| Glendale Adventist Medical Center Cancer Services | Glendale | California | 91206 | — |
| California Cancer Care | Greenbrae | California | 94904 | — |
| Beaver Medical Group, L.P. | Highland | California | 92346 | — |
| Breastlink Medical Group | Long Beach | California | 90806 | — |
| Long Beach Memorial Medical Center | Long Beach | California | 90806 | — |
| Facey Medical Group | Mission Hills | California | 91345 | — |
| Gynecologic Oncology Associates | Newport Beach | California | 92663 | — |
| Ventura County Hematology-Oncology Specialists | Oxnard | California | 93030 | — |
| Desert Hematology Oncology Medical Group, Inc | Rancho Mirage | California | 92270 | — |
| Helen Diller Family University of California San Francisco Comprehensive Cancer Center | San Francisco | California | 94115 | — |
| San Francisco Oncology Associates | San Francisco | California | 94115 | — |
| Redwood Regional Medical Group | Santa Rosa | California | 95403 | — |
| The Cancer Prevention and Treatment Center | Soquel | California | 95073 | — |
| Cancer Center of Central Connecticut | Southington | Connecticut | 06489 | — |
| Hematology Oncology, PC | Stamford | Connecticut | 06902 | — |
| Connecticut Oncology and Hematology | Torrington | Connecticut | 06790 | — |
| Washington Cancer Institute at Washington Hospital Center | Washington D.C. | District of Columbia | 20010 | — |
| Innovative Medical Research of South Florida, Inc. | Aventura | Florida | 33180 | — |
| University Cancer Institute, LLC | Boynton Beach | Florida | 33426 | — |
| North Broward Medical Center | Deerfield Beach | Florida | 33064 | — |
| Broward General Medical Center | Fort Lauderdale | Florida | 33316 | — |
| Florida Cancer Specialists and Research Institute | Gainesville | Florida | 32605 | — |
| Lakeland Regional Cancer Center | Lakeland | Florida | 33805 | — |
| Hematology Oncology Associates | Loxahatchee Groves | Florida | 33470 | — |
| Florida Cancer Affiliates - Ocala | Ocala | Florida | 34471 | — |
| Mid-Florida Hematology & Oncology Centers, PA | Orange City | Florida | 32763-8316 | — |
| Cancer Centers of Florida | Orlando | Florida | 32806 | — |
| M.D. Anderson Cancer Center Orlando | Orlando | Florida | 32806 | — |
| Florida Cancer Research Institute | Plantation | Florida | 33324 | — |
| Hematology Oncology Associates of Treasure Coast | Port Saint Lucie | Florida | 34592 | — |
| Florida Cancer Specialists, P.L. | St. Petersburg | Florida | 33705 | — |
| Oncology and Hematology of West Broward | Tamarac | Florida | 33321 | — |
| Florida Medical Clinic, P.A. | Zephyrhills | Florida | 33542 | — |
| Phoebe Cancer Center | Albany | Georgia | 31701 | — |
| Piedmont Cancer Institute | Atlanta | Georgia | 30318 | — |
| Augusta Oncology Associates (ACORN), P.C. | Augusta | Georgia | 30909 | — |
| Dwight David Eisenhower Army Medical Center | Fort Gordon | Georgia | 30905-5650 | — |
| Straub Clinic & Hospital | Honolulu | Hawaii | 96813-3083 | — |
| Portneuf Medical Center | Pocatello | Idaho | 83201 | — |
| Rush University Medical Center | Chicago | Illinois | 60612 | — |
| Cancer Care Specialists of Illinois, Decatur Memorial Hospital Clinical Research | Decatur | Illinois | 62526 | — |
| Midwest Center for Hematology/Oncology | Joliet | Illinois | 60432 | — |
| Medical Arts Associates, Ltd | Moline | Illinois | 61265 | — |
| Advocate Medical Group | Niles | Illinois | 60714 | — |
| Cancer Care & Hematology Specialists of Chicagoland | Niles | Illinois | 60714 | — |
| Quincy Medical Group, Cancer Center at Blessing Hospital | Quincy | Illinois | 62301 | — |
| North Shore Cancer Research Associates | Skokie | Illinois | 60076 | — |
| Orchard Healthcare Research, Inc. | Skokie | Illinois | 60076 | — |
| Orchard Research, LLC | Skokie | Illinois | 60076 | — |
| Simmons Cancer Institute | Springfield | Illinois | 62702 | — |
| Springfield Clinic, LLP | Springfield | Illinois | 62702 | — |
| Midwestern Regional Medical Center | Zion | Illinois | 60099 | — |
| Central Indiana Cancer Centers | Indianapolis | Indiana | 46219 | — |
| Hematology Oncology of Indiana | Indianapolis | Indiana | 46260-2082 | — |
| Community Hospital | Munster | Indiana | 46321 | — |
| Ashland-Bellefonte Cancer Center | Ashland | Kentucky | 41101-7016 | — |
| Purchase Cancer Group | Paducah | Kentucky | 42001 | — |
| Hematology-Oncology Clinic | Baton Rouge | Louisiana | 70809 | — |
| Crescent City Research Consortium, LLC | Marrero | Louisiana | 70072 | — |
| Central Maine Healthcare Corp | Lewiston | Maine | 04240 | — |
| Mercy Hospital Oncology/Hematology Center | Portland | Maine | 04102 | — |
| York Hospital Oncology Treatment Center | York Village | Maine | 03909 | — |
| Medical Oncology & Hematology Mercy Medical Center | Baltimore | Maryland | 21202 | — |
| Harry and Jeanette Weinberg Cancer Center | Baltimore | Maryland | 21237 | — |
| Alliance Hematology Oncology, PA Carroll County Cancer Center | Westminster | Maryland | 21157 | — |
| Massachusetts General Hospital | Boston | Massachusetts | 02114 | — |
| Massachusetts General Hospital - Gillette Center | Boston | Massachusetts | 02215 | — |
| University of Massachusetts Memorial Medical Center | Worcester | Massachusetts | 01655 | — |
| Barbara Ann Karmanos Cancer Institute | Detroit | Michigan | 48201-2013 | — |
| Cancer and Hematology Centers of Western Michigan | Grand Rapids | Michigan | 49503 | — |
| Medical Specialty Associates | Grand Rapids | Michigan | 49503 | — |
| Northern Michigan Hematology/Oncology | Petoskey | Michigan | 49770 | — |
| Minnesota Oncology Hematology, PA | Minneapolis | Minnesota | 55404 | — |
| Park Nicollet Institute | Saint Louis Park | Minnesota | 55426 | — |
| North Mississippi Hematology and Oncology Associates, Ltd. | Tupelo | Mississippi | 38801 | — |
| Capitol Comprehensive Cancer Care Clinic | Jefferson City | Missouri | 65109 | — |
| St. Joseph's Oncology | Saint Joseph | Missouri | 64507 | — |
| Mercy Medical Research Institute | Springfield | Missouri | 65807 | — |
| Washington University School of Medicine Siteman Cancer Center | St Louis | Missouri | 63110 | — |
| Montana Cancer Specialists | Missoula | Montana | 59802 | — |
| Southeast Nebraska Hematology & Oncology Consultants, PC | Lincoln | Nebraska | 68510 | — |
| Great Plains Regional Medical Center | North Platte | Nebraska | 69101 | — |
| The Center for Cancer and Hematologic Disease | Cherry Hill | New Jersey | 08003 | — |
| Trinitas Comprehensive Cancer Center | Elizabeth | New Jersey | 07207 | — |
| Saint Barnabas Health Care System | Livingston | New Jersey | 07039 | — |
| Summit Medical Group | Morristown | New Jersey | 07960 | — |
| Oncology and Hematology Specialist | Mountain Lakes | New Jersey | 07046 | — |
| Jersey Shore University Medical Center | Neptune City | New Jersey | 07754 | — |
| The Valley Hospital, Luckow Pavilion | Paramus | New Jersey | 07652 | — |
| Cooper University Hospital | Voorhees Township | New Jersey | 08043-4689 | — |
| ProHealth Care Associates | Lake Success | New York | 11042 | — |
| NYU Clinical Cancer Center | New York | New York | 10016 | — |
| Columbia University Medical Center, Herbert Irving Comprehensive Cancer Center | New York | New York | 10032 | — |
| Eastchester Center for Cancer Care | The Bronx | New York | 10469 | — |
| NorthEast Oncology Associates Carolinas Medical Center NorthEast | Concord | North Carolina | 28025 | — |
| Duke University Medical Center Medical Oncology | Durham | North Carolina | 27710 | — |
| Raleigh Hematology Oncology Associates Cancer Centers of North Carolina | Raleigh | North Carolina | 27607 | — |
| Hanover Medical Specialists, PA | Wilmington | North Carolina | 28401 | — |
| Mid Dakota Clinic, PC | Bismarck | North Dakota | 58501 | — |
| The Christ Hospital Cancer Center | Cincinnati | Ohio | 45219 | — |
| University of Cincinnati | Cincinnati | Ohio | 45267 | — |
| University Hospitals, Cleveland Medical Center | Cleveland | Ohio | 44106 | — |
| MetroHealth Medical Center | Cleveland | Ohio | 44109 | — |
| Signal Point Hematology/Oncology, Inc. | Middletown | Ohio | 45042 | — |
| Mercy Physicians of Oklahoma | Oklahoma City | Oklahoma | 73120 | — |
| Bend Memorial Clinic | Bend | Oregon | 97701 | — |
| Samaritan Hematology & Oncology Consultants | Corvallis | Oregon | 97330 | — |
| Northwest Cancer Specialist, P.C. | Portland | Oregon | 97213 | — |
| Providence Cancer Center Oncology and Hematology Care - Westside | Portland | Oregon | 97213 | — |
| Kaiser Permanente Northwest Region Oncology Hematology | Portland | Oregon | 97227-1110 | — |
| Oregon Health and Science University | Portland | Oregon | 97239 | — |
| Willamette Valley Cancer Institute and Research Center | Springfield | Oregon | 97477 | — |
| Oncology-Hematology of Lehigh Valley, PC | Bethlehem | Pennsylvania | 18015 | — |
| Gettysburg Cancer Center | Gettysburg | Pennsylvania | 17325 | — |
| Pinnacle Health Cancer Center Community Campus | Harrisburg | Pennsylvania | 17109 | — |
| Sweeney-Melenyser Pavillion | Monongahela | Pennsylvania | 15063 | — |
| Perelman Center for Advanced Medicine | Philadelphia | Pennsylvania | 19104 | — |
| Thomas Jefferson University | Philadelphia | Pennsylvania | 19107 | — |
| Temple University Hospital | Philadelphia | Pennsylvania | 19140 | — |
| Albert Einstein Cancer Center | Philadelphia | Pennsylvania | 19141 | — |
| Guthrie Clinic, Limited | Sayre | Pennsylvania | 18840 | — |
| Abington Hematology Oncology Associates, Inc | Willow Grove | Pennsylvania | 19090-1137 | — |
| Pawtuket Memorial Hospital | Pawtucket | Rhode Island | 02860 | — |
| Charleston Hematology Oncology Associates, PA | Charleston | South Carolina | 29414 | — |
| Medical University of South Carolina Hollings Cancer Center | Charleston | South Carolina | 29425 | — |
| Francisco Gonzalez MD PA | Columbia | South Carolina | 29203 | — |
| McLeod Oncology and Hematology Associates | Florence | South Carolina | 29506 | — |
| South Carolina Cancer Specialists | Hilton Head Island | South Carolina | 29926 | — |
| Santee Hematology Oncology | Sumter | South Carolina | 29150 | — |
| Avera Medical Oncology and Hematology - Avera Cancer Institute | Sioux Falls | South Dakota | 57105 | — |
| University Hematology/Oncology Associates PLLC | Chattanooga | Tennessee | 37403 | — |
| Cookeville Regional Cancer Center | Cookeville | Tennessee | 38501 | — |
| The Jones Clinic, PC | Germantown | Tennessee | 38138 | — |
| Thompson Cancer Survival Center | Knoxville | Tennessee | 37916 | — |
| Nashville Breast Center | Nashville | Tennessee | 37203 | — |
| Vanderbilt-Ingram Cancer Center | Nashville | Tennessee | 37232 | — |
| Texas Oncology, P.A. | Austin | Texas | 78731 | — |
| Texas Oncology, P.A. | Bedford | Texas | 76022 | — |
| Coastal Bend Cancer Center | Corpus Christi | Texas | 78404 | — |
| South Texas Institute of Cancer | Corpus Christi | Texas | 78405 | — |
| Cancer Specialists of South Texas, P.A. | Corpus Christi | Texas | 78412 | — |
| Center for Oncology Research | Dallas | Texas | 75230 | — |
| Texas Oncology, P.A. | Dallas | Texas | 75231-4400 | — |
| Texas Oncology - Baylor Charles A. Sammons Cancer Center | Dallas | Texas | 75246 | — |
| University of Texas Southwestern Medical Center Simmons Cancer Center | Dallas | Texas | 75390 | — |
| Texas Oncology, P.A. | Denton | Texas | 76210 | — |
| El Paso Cancer Treatment Center - West | El Paso | Texas | 79902 | — |
| Center for Integrative Cancer Medicine, PA | El Paso | Texas | 79912 | — |
| Texas Oncology | Fort Worth | Texas | 76104 | — |
| Texas Oncology, P.A. | Garland | Texas | 75042 | — |
| Texas Oncology - Memorial City | Houston | Texas | 77024 | — |
| The Methodist Hospital Breast Center | Houston | Texas | 77030 | — |
| Medicus Alliance Clinical Research Org., Inc. | Houston | Texas | 77055 | — |
| Jabboury Foundation for Cancer Research, Inc. | Houston | Texas | 77082 | — |
| Texas Oncology, P.A. | Paris | Texas | 75460 | — |
| Cancer Care Centers of South Texas | San Antonio | Texas | 78217 | — |
| South Texas Oncology & Hematology | San Antonio | Texas | 78229 | — |
| Texas Oncology P.A. | Sugar Land | Texas | 77479 | — |
| East Texas Medical Center Cancer Institute | Tyler | Texas | 75701 | — |
| Texas Oncology | Tyler | Texas | 75702 | — |
| Texas Oncology Cancer Care and Research Center | Waco | Texas | 76712 | — |
| North Utah Associates | Ogden | Utah | 84403 | — |
| Utah Cancer Specialists | Salt Lake City | Utah | 84106 | — |
| Southwestern Vermont Regional Cancer Center | Bennington | Vermont | 05201 | — |
| Rutland Regional Medical Center | Rutland | Vermont | 05701 | — |
| Inova Schar Cancer Institute | Fairfax | Virginia | 22031 | — |
| Virginia Cancer Specialists, PC | Fairfax | Virginia | 22031 | — |
| Virginia Oncology Associates | Norfolk | Virginia | 23502 | — |
| Cascade Cancer Center | Kirkland | Washington | 98034 | — |
| Cancer Care Northwest-North | Spokane | Washington | 99202 | — |
| Northwest Medical Specialties PLLC | Tacoma | Washington | 98405 | — |
| Wenatchee Valley Medical Center | Wenatchee | Washington | 98801 | — |
| West Virginia University Mary Babb Randolph Cancer Center | Morgantown | West Virginia | 26506 | — |
| Wheeling Hospital | Wheeling | West Virginia | 26003 | — |
| Aurora BayCare Medical Center | Green Bay | Wisconsin | 54311 | — |
| Wheaton Franciscan Cancer Care-All Saints | Racine | Wisconsin | 53405 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 309 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00878709, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jun 11, 2021 · Synced Oct 19, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00878709 live on ClinicalTrials.gov.