ARTEMIS-PH - Study of Ambrisentan in Subjects With Pulmonary Hypertension Associated With Idiopathic Pulmonary Fibrosis
Public ClinicalTrials.gov record NCT00879229. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3, Randomized, Double-Blind, Placebo-Controlled, Multi-Center, Parallel-Group Study to Evaluate the Efficacy and Safety of Ambrisentan in Subjects With Idiopathic Pulmonary Fibrosis and Pulmonary Hypertension
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
Ambrisentan is an endothelin receptor antagonist used for the treatment of pulmonary hypertension (PH). Based on research suggesting a role for endothelin-1 in the pathogenesis of idiopathic pulmonary fibrosis (IPF) and the poor prognosis for patients with IPF who are also diagnosed with PH, this study was designed to evaluate the effectiveness and safety of ambrisentan in that patient population.
Study identification
- NCT ID
- NCT00879229
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 40 participants
Conditions and interventions
Eligibility (public fields only)
- Age range
- 35 Years to 80 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jul 2009 (Type not available)
- Primary completion
- Feb 2011 (Actual)
- Completion
- Feb 2011 (Actual)
- Last update posted
- May 15, 2014
2009 – 2011
United States locations
- U.S. sites
- 51
- U.S. states
- 26
- U.S. cities
- 43
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama at Birmingham | Birmingham | Alabama | 35294 | — |
| Mayo Clinic Arizona | Scottsdale | Arizona | 85259 | — |
| University of California Davis | Davis | California | 95817 | — |
| David Geffen School of Medicine UCLA | Los Angeles | California | 90095 | — |
| University of California San Diego Medical Center | San Diego | California | 92103 | — |
| University of California at San Francisco | San Francisco | California | 94143 | — |
| Stanford University | Stanford | California | 94305 | — |
| University of Colorado Heatlh Sciences Center | Aurora | Colorado | 80045 | — |
| Bay Area Chest Physicians | Clearwater | Florida | 33756 | — |
| University of Florida | Gainesville | Florida | 32610 | — |
| University of Miami Medical Center | Miami | Florida | 33136 | — |
| Suncoast Lung Center | Sarasota | Florida | 34233 | — |
| Sarasota Memorial Hospital | Sarasota | Florida | 34239 | — |
| Cleveland Clinic Florida | Weston | Florida | 33331 | — |
| Atlanta Institute for Medical Research | Decatur | Georgia | 30030 | — |
| University of Chicago | Chicago | Illinois | 60637 | — |
| Kentuckiana Pulmonary Association | Louisville | Kentucky | — | — |
| Maine Medical Center | Portland | Maine | — | — |
| Johns Hopkins University School of Medicine | Baltimore | Maryland | 21205 | — |
| Tufts Medical Center | Boston | Massachusetts | 02111 | — |
| Brigham and Women's Hospital | Boston | Massachusetts | 02115 | — |
| Boston University Medical Center | Boston | Massachusetts | 02118 | — |
| Beth Israel Deacones Medical Center | Boston | Massachusetts | 02215 | — |
| University of Michigan Health Systems | Ann Arbor | Michigan | 48109 | — |
| Mayo Clinic Rochester | Rochester | Minnesota | 55905 | — |
| Washington University | St Louis | Missouri | 63110 | — |
| Creighton University Center for Allergy & Asthma | Omaha | Nebraska | 68131 | — |
| Dartmouth Medical School | Lebanon | New Hampshire | 03756 | — |
| Albany Medical Center | Albany | New York | 12208 | — |
| Winthrop University Hospital | Mineola | New York | 11501 | — |
| North Shore Health System | New Hyde Park | New York | 11040 | — |
| Mount Sinai School of Medicine | New York | New York | 10029 | — |
| Columbia University | New York | New York | 10032 | — |
| University of North Carolina at Chapel Hill | Chapel Hill | North Carolina | 27599 | — |
| Duke University Medical Center | Durham | North Carolina | 27710 | — |
| The Lindner Center for Research & Education at The Christ Hospital | Cincinnati | Ohio | 45219 | — |
| University Hospitals of Cleveland Case Western | Cleveland | Ohio | 44106 | — |
| Cleveland Clinic Foundation | Cleveland | Ohio | 44195 | — |
| Ohio State University | Columbus | Ohio | 43210 | — |
| Hospital of the University of Pennsylvania | Philadelphia | Pennsylvania | 19104 | — |
| Temple University School of Medicine | Philadelphia | Pennsylvania | 19140 | — |
| Alleghany General Hospital | Pittsburgh | Pennsylvania | 12512 | — |
| University of Pittsburgh Cancer Institute | Pittsburgh | Pennsylvania | 15213 | — |
| Medical University of South Carolina | Charleston | South Carolina | — | — |
| Vanderbilt University Medical Center | Nashville | Tennessee | 37232 | — |
| University of Texas Southwestern | Dallas | Texas | 75390 | — |
| Baylor College of Medicine | Houston | Texas | 77030 | — |
| University of Utah | Salt Lake City | Utah | 84108 | — |
| Inova Heart Institiute and Vascular Institute | Falls Church | Virginia | 22042 | — |
| Virginia Commonwealth University Health System | Richmond | Virginia | 23298 | — |
| Providence Everett Medical Center | Everett | Washington | 98201 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 34 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00879229, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 15, 2014 · Synced Oct 21, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00879229 live on ClinicalTrials.gov.