Plaque Inflammation and Dysfunctional HDL in AIM-HIGH
Public ClinicalTrials.gov record NCT00880178. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
Coronary heart disease (CHD) is a serious health concern that affects millions of people in the United States. It is usually caused by atherosclerosis-a condition that occurs when fatty material and plaque build up on the walls of the arteries that supply blood and oxygen to the heart, causing the arteries to narrow. As the arteries narrow, blood flow to the heart can slow down or stop, which can cause chest pain, shortness of breath, heart attack, or heart failure. Another component of CHD events involves inflammatory changes that result in structural breakdown of atherosclerotic plaques. Adding niacin to statin medications may be an effective way to block inflammation in the atherosclerotic plaques. This study will examine magnetic resonance imaging (MRI) images and blood samples of participants in the AIM-HIGH study who are taking niacin plus statins or statins alone to determine the effect of these medications on inflammation in atherosclerotic plaques.
Study identification
- NCT ID
- NCT00880178
- Recruitment status
- Completed
- Study type
- Observational
- Phase
- Not listed
- Enrollment
- 324 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 45 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- May 2008 (Type not available)
- Primary completion
- Aug 2011 (Actual)
- Completion
- Sep 2011 (Actual)
- Last update posted
- May 14, 2018
2008 – 2011
United States locations
- U.S. sites
- 24
- U.S. states
- 13
- U.S. cities
- 16
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Cardiovascular Associates | Birmingham | Alabama | 35213 | — |
| Cardiovascular Consultants | Phoenix | Arizona | 85032 | — |
| Long Beach VA Medical Center | Long Beach | California | 90822 | — |
| Christiana Care Health Services | Newark | Delaware | 19718 | — |
| University of Maryland | Baltimore | Maryland | 21201 | — |
| University of Minnesota | Minneapolis | Minnesota | 55414 | — |
| HealthPartners Riverside Clinic | Minneapolis | Minnesota | 55454 | — |
| Mayo Clinic | Rochester | Minnesota | 55905 | — |
| Duke University | Durham | North Carolina | 27710 | — |
| Wake Forest University, Geriatrics | Greensboro | North Carolina | 27157 | — |
| Wake Forest University, Cardiology | Winston-Salem | North Carolina | 27157 | — |
| Wake Forest University, Endocrinology | Winston-Salem | North Carolina | 27157 | — |
| St. Vincent Charity Hospital | Cleveland | Ohio | 44115 | — |
| Portland VA Medical Center | Portland | Oregon | 97239 | — |
| Philadelphia VA Medical Center | Philadelphia | Pennsylvania | 19104 | — |
| Pennsylvania Cardiology Associates | Philadelphia | Pennsylvania | 19106 | — |
| Cardiology Consultants of Philadelphia | Philadelphia | Pennsylvania | 19148 | — |
| Baylor College of Medicine | Houston | Texas | 77030 | — |
| Kelsey Research Foundation | Houston | Texas | 77030 | — |
| Methodist Hospital | Houston | Texas | 77030 | — |
| McGuire VA Medical Center | Richmond | Virginia | 23249 | — |
| Harborview Medical Center | Seattle | Washington | 98104 | — |
| University of Washington | Seattle | Washington | 98105 | — |
| Puget Sound VA Medical Center, Seattle Campus | Seattle | Washington | 98108 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 5 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00880178, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 14, 2018 · Synced Oct 20, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00880178 live on ClinicalTrials.gov.