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Completed Phase 1 Interventional

Cixutumumab and Temsirolimus in Treating Younger Patients With Solid Tumors That Have Recurred or Not Responded to Treatment

ClinicalTrials.gov ID: NCT00880282

Public ClinicalTrials.gov record NCT00880282. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced May 6, 2026, 2:03 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase I Study of IMC-A12 (Anti-Insulin-Like Growth Factor-I Receptor Monoclonal Antibody) in Combination With CCI-779 (Temsirolimus) in Pediatric Patients With Recurrent or Refractory Solid Tumors

Study identification

NCT ID
NCT00880282
Recruitment status
Completed
Study type
Interventional
Phase
Phase 1
Lead sponsor
National Cancer Institute (NCI)
NIH
Enrollment
39 participants

Conditions and interventions

Interventions

  • cixutumumab Biological
  • laboratory biomarker analysis Other
  • pharmacological study Other
  • temsirolimus Drug

Biological · Other · Drug

Eligibility (public fields only)

Age range
1 Year to 21 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Mar 31, 2009
Primary completion
Sep 30, 2012
Completion
Not listed
Last update posted
Apr 28, 2014

Started 2009

United States locations

U.S. sites
21
U.S. states
18
U.S. cities
20
Facility City State ZIP Site status
University of Alabama at Birmingham Birmingham Alabama 35294
Childrens Hospital of Orange County Orange California 92868-3874
Children's National Medical Center Washington D.C. District of Columbia 20010
Lurie Children's Hospital-Chicago Chicago Illinois 60614
Indiana University Medical Center Indianapolis Indiana 46202
Riley Hospital for Children Indianapolis Indiana 46202
Mark O Hatfield-Warren Grant Magnuson Clinical Center Bethesda Maryland 20892
Dana-Farber Cancer Institute Boston Massachusetts 02115
C S Mott Children's Hospital Ann Arbor Michigan 48109
University of Minnesota Medical Center-Fairview Minneapolis Minnesota 55455
Washington University School of Medicine St Louis Missouri 63110
Columbia University Medical Center New York New York 10032
Cincinnati Children's Hospital Medical Center Cincinnati Ohio 45229
Oregon Health and Science University Portland Oregon 97239
Children's Hospital of Philadelphia Philadelphia Pennsylvania 19104
Children's Hospital of Pittsburgh of UPMC Pittsburgh Pennsylvania 15224
St. Jude Children's Research Hospital Memphis Tennessee 38105
University of Texas Southwestern Medical Center Dallas Texas 75390
Baylor College of Medicine Houston Texas 77030
Seattle Children's Hospital Seattle Washington 98105
Midwest Children's Cancer Center Milwaukee Wisconsin 53226

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 2 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00880282, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Apr 28, 2014 · Synced May 6, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT00880282 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →