Effect of Reward on Learning in Motor Cortex
Public ClinicalTrials.gov record NCT00885131. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Effects of Reward on Learning in the Motor Cortex
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
Background: * Magnetic resonance imaging (MRI) uses a strong magnetic field and radio waves to take pictures of the brain. Some MRI studies suggest that this technique reveals brain differences in patients with a nervous system illness when compared to adults without a nervous system illness. Objectives: * To study functional changes in the brain that may be observed in people without any nervous system illness. * To learn more about which areas of the brain are necessary to perform certain tasks, especially learning simple motor sequences and processing rewards. Eligibility: * Healthy volunteers between the ages of 18 and 50 who are right-handed and are native English speakers, and who have no medical conditions that would prevent them from undergoing magnetic imaging. * Volunteers must not have a history of neurological or psychiatric illnesses. * Female volunteers must not be pregnant. Design: * Volunteers will be asked to undergo different types of magnetic imaging, including functional magnetic resonance imaging (fMRI), magnetic resonance spectroscopy (MRS), and/or transcranial magnetic stimulation (TMS), while participating in either a slot machine simulation or a key sequence learning task. * Volunteers will participate in one of four possible experiments: * Experiment 1: MRS/TMS and slot machine (3 visits, 3.5 hours in total). * Experiment 2: MRS/TMS and key sequence (3 visits, 3.5 hours in total). * Experiment 3: fMRI and slot machine (2 visits, 3 hours in total). * Experiment 4: fMRI and key sequence (1 visit, 2 hours in total). * Experiment types: * Slot machine: A computer game like a slot machine, where the user presses a button to start the game and watches as the three barrels of the machine spin into place. * Key sequence: Pressing a series of buttons in response to visual cues. * Volunteers will also be asked to give a small blood sample for genetic testing. * Volunteers will be paid a small amount of money (approximately $50 $80) during the experiments in compensation for their participation in the study.
Study identification
- NCT ID
- NCT00885131
- Recruitment status
- Completed
- Study type
- Observational
- Phase
- Not listed
- Enrollment
- 64 participants
Conditions and interventions
Conditions
Interventions
Not listed
Eligibility (public fields only)
- Age range
- 18 Years to 50 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Apr 14, 2009
- Primary completion
- Not listed
- Completion
- Jan 21, 2013
- Last update posted
- Dec 8, 2019
2009 – 2013
United States locations
- U.S. sites
- 1
- U.S. states
- 1
- U.S. cities
- 1
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| National Institutes of Health Clinical Center, 9000 Rockville Pike | Bethesda | Maryland | 20892 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00885131, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Dec 8, 2019 · Synced Sep 12, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT00885131 live on ClinicalTrials.gov.