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Completed Phase 3 Interventional Results available

Efficacy and Safety Study of Saxagliptin + Metformin Immediate Release (IR) Versus Metformin IR Alone in Type 2 Diabetes Mellitus

ClinicalTrials.gov ID: NCT00885378

Public ClinicalTrials.gov record NCT00885378. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 2, 2026, 12:59 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Multicenter, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, Phase 3 Trial to Evaluate the Efficacy and Safety of 2.5 mg Saxagliptin, Twice Daily, in Combination With Metformin IR in Subjects With Type 2 Diabetes Mellitus Who Have Inadequate Glycemic Control on Metformin IR Alone

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The purpose of this study is to compare the reduction in hemoglobin A1C (A1C) for participants taking saxagliptin in combination with metformin immediate release (IR) versus metformin IR alone.

Study identification

NCT ID
NCT00885378
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Lead sponsor
AstraZeneca
Industry
Enrollment
166 participants

Conditions and interventions

Eligibility (public fields only)

Age range
18 Years to 78 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Apr 30, 2009
Primary completion
Jan 31, 2010
Completion
Jan 31, 2010
Last update posted
May 31, 2015

2009 – 2010

United States locations

U.S. sites
25
U.S. states
13
U.S. cities
25
Facility City State ZIP Site status
John Muir Physician Network Clinical Research Center Concord California 94520
Southland Clinical Research Center, Inc. Fountain Valley California 92708
Torrance Clinical Research Lomita California 90717
Ritchken & First M.D.'S San Diego California 92117
Central Florida Clinical Trials, Inc. Altamonte Springs Florida 32701
Family Care Associates Of Nw Florida Chipley Florida 32428
Clinical Therapeutics Corporation Coral Gables Florida 33134
Nextphase Clinical Trials, Inc. Miami Florida 33145
Middle Georgia Drug Study Center, Llc Perry Georgia 31069
Louisiana Heart Center Research Slidell Louisiana 70458
Jackson Clinic Rolling Fork Mississippi 39159
Community Health Care Of Manchester Akron Ohio 44319
Midwest Regional Research, Inc. Bellbrook Ohio 45305
Wells Institute For Health Awareness Kettering Ohio 45429
Newark Physician Associates Newark Ohio 43055
Integris Family Care South Oklahoma City Oklahoma 73170
Integris Family Care Yukon Yukon Oklahoma 73099
Williamette Valley Clinical Studies Eugene Oregon 97404
Integrated Medical Group Pc/Fleetwood Clinical Research Fleetwood Pennsylvania 19522
Southeastern Research Associates, Inc Taylors South Carolina 29687
Holston Medical Group Kingsport Tennessee 37660
Village Family Practice Houston Texas 77024
Southwest Clinical Research Centers, Llc Pearland Texas 77584
Jolene K. Berg, Md., Dgd Research, Inc. San Antonio Texas 78229
Tidewater Integrated Medical Research Virginia Beach Virginia 23454

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 16 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00885378, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted May 31, 2015 · Synced Sep 2, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT00885378 live on ClinicalTrials.gov.

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