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Completed Phase 3 Interventional Results available

A Study Of Tocilizumab in Patients With Moderate to Severe Active Rheumatoid Arthritis Who Have an Inadequate Response to or Are Unable to Tolerate Biologic and Non-Biologic Disease-modifying Antirheumatic Drugs (DMARDs)

ClinicalTrials.gov ID: NCT00891020

Public ClinicalTrials.gov record NCT00891020. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

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ClinicalTrials.gov public records Last synced Jul 22, 2026, 1:18 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Open-Label Study to Evaluate the Safety, Tolerability and Efficacy of Tocilizumab in Patients With Active Rheumatoid Arthritis on Background Non-biologic DMARDs and Monotherapy Who Have an Inadequate Response to Current Non-Biologic or Biologic DMARDs

Study identification

NCT ID
NCT00891020
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Lead sponsor
Hoffmann-La Roche
Industry
Enrollment
886 participants

Conditions and interventions

Interventions

  • tocilizumab [RoActemra/Actemra] Drug
  • Nonbiologic DMARDs of investigator's choice Drug

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Apr 30, 2009
Primary completion
Jun 30, 2010
Completion
Feb 28, 2011
Last update posted
Oct 24, 2012

2009 – 2011

United States locations

U.S. sites
227
U.S. states
43
U.S. cities
204
Facility City State ZIP Site status
Not listed Anniston Alabama 36207 —
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Not listed Huntsville Alabama 35801 —
Not listed Mobile Alabama 36608 —
Not listed Montgomery Alabama 36111 —
Not listed Tuscaloosa Alabama 35406 —
Not listed Hot Springs Arizona 71913 —
Not listed Paradise Valley Arizona 85253 —
Not listed Peoria Arizona 85381 —
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Not listed Tucson Arizona 85704 —
Not listed Fayetteville Arkansas 27203 —
Not listed Fort Smith Arkansas 72903 —
Not listed Jonesboro Arkansas 72401 —
Not listed Little Rock Arkansas 72205 —
Not listed Covina California 91723 —
Not listed Escondido California 92025 —
Not listed Fullerton California 92835 —
Not listed Huntington Beach California 92646 —
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Not listed Long Beach California 90808 —
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Not listed Trumbull Connecticut 06611 —
Not listed Lewes Delaware 19958 —
Not listed Aventura Florida 33180 —
Not listed Boca Raton Florida 33486 —
Not listed Clearwater Florida 33761 —
Not listed Dunedin Florida 34698 —
Not listed Fort Lauderdale Florida 33334 —
Not listed Gainesville Florida 30501 —
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Not listed Atlanta Georgia 30342 —
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Not listed Morton Grove Illinois 60053 —
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Not listed Schaumburg Illinois 60195 —
Not listed Springfield Illinois 62704 —
Not listed Vernon Hills Illinois 60061 —
Not listed Evansville Indiana 47714 —
Not listed Fort Wayne Indiana 46804 —
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Not listed Cedar Rapids Iowa 52401 —
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Not listed Columbia Maryland 21045 —
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Not listed Pascagoula Massachusetts 39581 —
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Not listed Battle Creek Michigan 49015 —
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Not listed Duluth Minnesota 55805 —
Not listed Eagan Minnesota 55121 —
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Not listed Flowood Mississippi 39232 —
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Not listed Florissant Missouri 63031 —
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Not listed Grand Island Nebraska 68803 —
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Not listed Reno Nevada 89502 —
Not listed Dover New Hampshire 03820 —
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Not listed Clifton New Jersey 07012 —
Not listed Haddon Heights New Jersey 08035 —
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Not listed New Brunswick New Jersey 08903 —
Not listed Trenton New Jersey 08360 —
Not listed Voorhees Township New Jersey 08043 —
Not listed Las Cruces New Mexico 88011 —
Not listed Albany New York 12206 —
Not listed Binghamton New York 13905 —
Not listed Brooklyn New York 11201 —
Not listed Cooperstown New York 13326 —
Not listed Hewlett New York 11557 —
Not listed Lake Success New York 11042 —
Not listed New York New York 10016 —
Not listed Olean New York 14760 —
Not listed Orchard Park New York 14127 —
Not listed Plainview New York 11803 —
Not listed Rochester New York 14618 —
Not listed Roslyn New York 11576 —
Not listed Smithtown New York 11787 —
Not listed Syracuse New York 13210 —
Not listed Utica New York 13504 —
Not listed Asheville North Carolina 28803 —
Not listed Belmont North Carolina 28012 —
Not listed Charlotte North Carolina 28204 —
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Not listed Durham North Carolina 27704 —
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Not listed Raleigh North Carolina 27609 —
Not listed Rock Hill North Carolina 29732 —
Not listed Wilmington North Carolina 28401 —
Not listed Bismarck North Dakota 58501 —
Not listed Akron Ohio 44333 —
Not listed Cincinnati Ohio 45219 —
Not listed Cincinnati Ohio 45255 —
Not listed Columbus Ohio 43210 —
Not listed Columbus Ohio 43215 —
Not listed Dayton Ohio 45402 —
Not listed Gallipolis Ohio 45631 —
Not listed Mayfield Ohio 44143 —
Not listed Middleburg Heights Ohio 44130 —
Not listed Perryburg Ohio 43551 —
Not listed Zanesville Ohio 43701 —
Not listed Oklahoma City Oklahoma 73103 —
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Not listed Tulsa Oklahoma 74135 —
Not listed Lake Oswego Oregon 97035 —
Not listed Bethlehem Pennsylvania 18015 —
Not listed Camp Hill Pennsylvania 17011 —
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Not listed Lebanon Pennsylvania 17042 —
Not listed Philadelphia Pennsylvania 19141 —
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Not listed Pottstown Pennsylvania 19464 —
Not listed West Reading Pennsylvania 19611 —
Not listed Wexford Pennsylvania 15090 —
Not listed Willow Grove Pennsylvania 19090 —
Not listed Charleston South Carolina 29406 —
Not listed Columbia South Carolina 29204 —
Not listed Hickory Grove South Carolina 28602 —
Not listed Myrtle Beach South Carolina 29572 —
Not listed Hendersonville Tennessee 37073 —
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Not listed Knoxville Tennessee 37909 —
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Not listed Amarillo Texas 79106 —
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Not listed Mesquite Texas 75150 —
Not listed Nassau Bay Texas 77058 —
Not listed San Antonio Texas 78217 —
Not listed San Antonio Texas 78229 —
Not listed San Antonio Texas 78258 —
Not listed Tyler Texas 75701 —
Not listed Waco Texas 76708 —
Not listed Burlington Vermont 05401 —
Not listed Arlington Virginia 22205 —
Not listed Burke Virginia 22015 —
Not listed Richmond Virginia 23294 —
Not listed Virginia Beach Virginia 23454 —
Not listed Olympia Washington 98502 —
Not listed Spokane Washington 99204 —
Not listed Tacoma Washington 98405 —
Not listed Beckley West Virginia 25801 —
Not listed Clarksburg West Virginia 26301 —
Not listed Brookfield Wisconsin 53045 —
Not listed Franklin Wisconsin 53132 —
Not listed Glendale Wisconsin 53217 —
Not listed Milwaukee Wisconsin 53209 —
Not listed Onalaska Wisconsin 54605 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00891020, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Oct 24, 2012 · Synced Jul 22, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT00891020 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →