A Study of Ranibizumab Administered Monthly or on an As-needed Basis in Patients With Subfoveal Neovascular Age-related Macular Degeneration (HARBOR)
Public ClinicalTrials.gov record NCT00891735. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase III, Double-masked, Multicenter, Randomized, Active Treatment-controlled Study of the Efficacy and Safety of 0.5 mg and 2.0 mg Ranibizumab Administered Monthly or on an As-needed Basis (PRN) in Patients With Subfoveal Neovascular Age-related Macular Degeneration
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This is a Phase III, multicenter, randomized, double-masked, dose-comparison study of the efficacy and safety of ranibizumab injection administered intravitreally to patients with choroidal neovascularization (CNV) secondary to age-related macular degeneration (AMD). Results are presented for the first 12 months of the study.
Study identification
- NCT ID
- NCT00891735
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 1,097 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 50 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jul 2009 (Type not available)
- Primary completion
- Aug 2011 (Actual)
- Completion
- Aug 2012 (Actual)
- Last update posted
- Jan 18, 2013
2009 – 2012
United States locations
- U.S. sites
- 99
- U.S. states
- 33
- U.S. cities
- 94
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Not listed | Phoenix | Arizona | 85020 | — |
| Not listed | Tucson | Arizona | 85704 | — |
| Not listed | Arcadia | California | 91007 | — |
| Not listed | Beverly Hills | California | 90211 | — |
| Not listed | Campbell | California | 95008 | — |
| Not listed | Chico | California | 95973 | — |
| Not listed | La Jolla | California | 92093-0946 | — |
| Not listed | Los Angeles | California | 90033 | — |
| Not listed | Los Angeles | California | 90095-7000 | — |
| Not listed | Mountain View | California | 94040 | — |
| Not listed | Oakland | California | 94609 | — |
| Not listed | Palm Desert | California | 92211 | — |
| Not listed | Poway | California | 92064 | — |
| Not listed | Sacramento | California | 95817 | — |
| Not listed | San Francisco | California | 94107 | — |
| Not listed | San Francisco | California | 94115 | — |
| Not listed | Santa Ana | California | 92705 | — |
| Not listed | Santa Barbara | California | 93103 | — |
| Not listed | Torrance | California | 90503 | — |
| Not listed | Ventura | California | 93003 | — |
| Not listed | Westlake Village | California | 91361 | — |
| Not listed | Aurora | Colorado | 80045 | — |
| Not listed | Colorado Springs | Colorado | 80909 | — |
| Not listed | Golden | Colorado | 80401 | — |
| Not listed | Danbury | Connecticut | 06810 | — |
| Not listed | Hamden | Connecticut | 06518 | — |
| Not listed | New Haven | Connecticut | 06510 | — |
| Not listed | New London | Connecticut | 06320 | — |
| Not listed | Altamonte Springs | Florida | 32701 | — |
| Not listed | Boynton Beach | Florida | 33426 | — |
| Not listed | Fort Lauderdale | Florida | 33334 | — |
| Not listed | Fort Myers | Florida | 33912 | — |
| Not listed | Palm Beach Gardens | Florida | 33410 | — |
| Not listed | Pensacola | Florida | 32503 | — |
| Not listed | Stuart | Florida | 34994 | — |
| Not listed | Tampa | Florida | 33609 | — |
| Not listed | Tampa | Florida | 33612 | — |
| Not listed | Winter Haven | Florida | 33880 | — |
| Not listed | Augusta | Georgia | 30909 | — |
| Not listed | ‘Aiea | Hawaii | 96701 | — |
| Not listed | Chicago | Illinois | 60637 | — |
| Not listed | Oak Park | Illinois | 60304 | — |
| Not listed | Indianapolis | Indiana | 46290 | — |
| Not listed | Shawnee Mission | Kansas | 66204 | — |
| Not listed | Wichita | Kansas | 67214 | — |
| Not listed | Lexington | Kentucky | 40509 | — |
| Not listed | Paducah | Kentucky | 42001 | — |
| Not listed | Portland | Maine | 04102 | — |
| Not listed | Baltimore | Maryland | 21287 | — |
| Not listed | Hagerstown | Maryland | 21740 | — |
| Not listed | Boston | Massachusetts | 02111 | — |
| Not listed | Boston | Massachusetts | 02114 | — |
| Not listed | Worcester | Massachusetts | 01605 | — |
| Not listed | Jackson | Michigan | 49201 | — |
| Not listed | Edina | Minnesota | 55435 | — |
| Not listed | St Louis | Missouri | 63144 | — |
| Not listed | Lincoln | Nebraska | 68506 | — |
| Not listed | Las Vegas | Nevada | 89144 | — |
| Not listed | Lawrenceville | New Jersey | 08648 | — |
| Not listed | New Brunswick | New Jersey | 08901 | — |
| Not listed | Northfield | New Jersey | 08225 | — |
| Not listed | Teaneck | New Jersey | 07666 | — |
| Not listed | Vauxhall | New Jersey | 07088 | — |
| Not listed | Great Neck | New York | 11021 | — |
| Not listed | Lynbrook | New York | 11563 | — |
| Not listed | New York | New York | 10021 | — |
| Not listed | Rochester | New York | 14620 | — |
| Not listed | Shirley | New York | 11967 | — |
| Not listed | Asheville | North Carolina | 28803 | — |
| Not listed | Charlotte | North Carolina | 28210 | — |
| Not listed | Beachwood | Ohio | 44122 | — |
| Not listed | Cincinnati | Ohio | 45242 | — |
| Not listed | Columbus | Ohio | 43212 | — |
| Not listed | Portland | Oregon | 97210 | — |
| Not listed | Camp Hill | Pennsylvania | 17011 | — |
| Not listed | Huntingdon Valley | Pennsylvania | 19006 | — |
| Not listed | Johnstown | Pennsylvania | 15904 | — |
| Not listed | Philadelphia | Pennsylvania | 19107 | — |
| Not listed | Pittsburgh | Pennsylvania | 15212 | — |
| Not listed | Pittsburgh | Pennsylvania | 15213 | — |
| Not listed | West Mifflin | Pennsylvania | 15122 | — |
| Not listed | Greenville | South Carolina | 29605 | — |
| Not listed | Ladson | South Carolina | 29456 | — |
| Not listed | West Columbia | South Carolina | 29169 | — |
| Not listed | Rapid City | South Dakota | 57701 | — |
| Not listed | Nashville | Tennessee | 37203 | — |
| Not listed | Abilene | Texas | 79606 | — |
| Not listed | Austin | Texas | 78705 | — |
| Not listed | DeSoto | Texas | 75115 | — |
| Not listed | Houston | Texas | 77030 | — |
| Not listed | McAllen | Texas | 78503 | — |
| Not listed | San Antonio | Texas | 78240 | — |
| Not listed | Temple | Texas | 76508 | — |
| Not listed | The Woodlands | Texas | 77384 | — |
| Not listed | Salt Lake City | Utah | 84107 | — |
| Not listed | Richmond | Virginia | 23235 | — |
| Not listed | Virginia Beach | Virginia | 23454 | — |
| Not listed | Milwaukee | Wisconsin | 53226 | — |
| Not listed | Casper | Wyoming | 82601 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00891735, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jan 18, 2013 · Synced Oct 18, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00891735 live on ClinicalTrials.gov.