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Completed Phase 2 Interventional Results available

Study of the Combination Therapy of Rt-PA and Eptifibatide to Treat Acute Ischemic Stroke

ClinicalTrials.gov ID: NCT00894803

Public ClinicalTrials.gov record NCT00894803. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 23, 2026, 10:18 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

The "Combined Approach to Lysis Utilizing Eptifibatide and Rt-PA in Acute Ischemic Stroke-Enhanced Regimen" (CLEAR-ER Stroke Trial)

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The primary goal of this trial is to determine if individuals with acute ischemic stroke treated with a medium dose of IV rt-PA plus IV eptifibatide started within 3 hours of symptom onset are more likely to have a better outcome than individuals treated with standard IV rt-PA alone.

Study identification

NCT ID
NCT00894803
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
University of Cincinnati
Other
Enrollment
126 participants

Conditions and interventions

Eligibility (public fields only)

Age range
18 Years to 85 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jul 2009 (Type not available)
Primary completion
Oct 2012 (Actual)
Completion
Dec 2012 (Actual)
Last update posted
Apr 17, 2014

2009 – 2012

United States locations

U.S. sites
20
U.S. states
10
U.S. cities
14
Facility City State ZIP Site status
UCLA Ronald Reagan Medical Center Los Angeles California 90024 —
University of California San Diego San Diego California 92103 —
UCLA Medical Center Santa Monica Santa Monica California 90404 —
Washington Hospital Center Washington D.C. District of Columbia 20010 —
St. Elizabeth Healthcare Edgewood Edgewood Kentucky 41017 —
St. Elizabeth Healthcare Florence Florence Kentucky 41042 —
St. Elizabeth Healthcare Ft. Thomas Fort Thomas Kentucky 41075 —
Suburban Hospital Bethesda Maryland 20814 —
University of Michigan Medical Center Ann Arbor Michigan 48109 —
Robert Wood Johnson University Hospital New Brunswick New Jersey 08903 —
Mission Hospital, Inc. Asheville North Carolina 28801 —
The Christ Hospital Cincinnati Ohio 45219 —
University Hospital Cincinnati Ohio 45219 —
Good Samaritan Hospital Cincinnati Ohio 45220-2489 —
The Jewish Hospital Cincinnati Ohio 45236 —
Mercy Hospital, Western Hills Cincinnati Ohio 45238 —
Mercy Hospital Mt Airy Cincinnati Ohio 45239 —
Bethesda North Hospital Cincinnati Ohio 45242 —
Hospital of the University of Pennsylvania Philadelphia Pennsylvania 19104 —
West Virginia University Hospital Morgantown West Virginia 26506 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00894803, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Apr 17, 2014 · Synced Oct 23, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT00894803 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →