Macitentan Use in an Idiopathic Pulmonary Fibrosis Clinical Study
Public ClinicalTrials.gov record NCT00903331. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Double-blind, Randomized, Placebo-controlled, Multicenter, Parallel Group Study to Evaluate the Efficacy, Safety, and Tolerability of Macitentan in Patients With Idiopathic Pulmonary Fibrosis
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The AC-055B201/MUSIC study is a Phase II study, comparing one dose of ACT-064922 (macitentan) 10 mg with placebo in patients with idiopathic pulmonary fibrosis (IPF). The main study objective is to demonstrate that macitentan positively affects the forced vital capacity (FVC) in comparison with placebo in patients with idiopathic pulmonary fibrosis (IPF). The secondary objectives are to evaluate the effect of macitentan on the time to disease worsening or death in patients with IPF, and to evaluate the benefit/risk profile of macitentan in the treatment of patients with IPF.
Study identification
- NCT ID
- NCT00903331
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 178 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- May 2009 (Type not available)
- Primary completion
- Jun 2011 (Actual)
- Completion
- Aug 2011 (Actual)
- Last update posted
- Feb 17, 2014
2009 – 2011
United States locations
- U.S. sites
- 15
- U.S. states
- 11
- U.S. cities
- 15
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama at Birmingham | Birmingham | Alabama | 35294 | — |
| Pulmonary Associates, P.A. | Phoenix | Arizona | 85006 | — |
| Mayo Clinic - Arizona | Scottsdale | Arizona | 85259 | — |
| U.C. Davis University of California | Sacramento | California | 95817 | — |
| UCSD Pulmonary Critical Care | San Diego | California | 92103 | — |
| University of California - San Francisco | San Francisco | California | 94143 | — |
| Stanford University Medical Center - Chest Clinic | Stanford | California | 94305 | — |
| National Jewish Medical & Research Center | Denver | Colorado | 80206 | — |
| Yale University School of Medicine | New Haven | Connecticut | 06520 | — |
| Wichita Clinic P.A | Wichita | Kansas | 67208 | — |
| St. Luke's Medical Group | Chesterfield | Missouri | 63017 | — |
| The Cleveland Clinic Foundation | Cleveland | Ohio | 44195 | — |
| Temple University Hospital - Lung Center | Philadelphia | Pennsylvania | 19140 | — |
| Baylor College of Medicine - Baylor Clinic | Houston | Texas | 77030 | — |
| University of Wisconsin - Madison | Madison | Wisconsin | 53792 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 38 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00903331, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Feb 17, 2014 · Synced Oct 17, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00903331 live on ClinicalTrials.gov.