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Completed Phase 1 Interventional

MLN4924 for the Treatment of Acute Myelogenous Leukemia, Myelodysplastic Syndrome, and Acute Lymphoblastic Leukemia

ClinicalTrials.gov ID: NCT00911066

Public ClinicalTrials.gov record NCT00911066. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Jun 26, 2026, 7:26 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

An Open-Label, Dose Escalation, Phase 1 Study of MLN4924, a Novel Inhibitor of Nedd8-Activating Enzyme, in Adult Patients With Acute Myelogenous Leukemia,Myelodysplastic Syndrome, and Acute Lymphoblastic Leukemia

Study identification

NCT ID
NCT00911066
Recruitment status
Completed
Study type
Interventional
Phase
Phase 1
Lead sponsor
Millennium Pharmaceuticals, Inc.
Industry
Enrollment
72 participants

Conditions and interventions

Interventions

  • MLN4924 Drug
  • Azacitidine Drug

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
May 31, 2009
Primary completion
Jul 31, 2013
Completion
Sep 30, 2013
Last update posted
Dec 4, 2013

2009 – 2013

United States locations

U.S. sites
6
U.S. states
6
U.S. cities
6
Facility City State ZIP Site status
Stanford University Medical Center Stanford California 94305
Robert H. Lurie Comprehensive Cancer Center Northwestern University Chicago Illinois 60657
Johns Hopkins Kimmel Cancer Center Baltimore Maryland 21287
Dana Farber Cancer Institute Boston Massachusetts 02115
University of Michigan Comprehensive Cancer Center Ann Arbor Michigan 48109
Institute for Drug Development San Antonio Texas 78229

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00911066, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Dec 4, 2013 · Synced Jun 26, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT00911066 live on ClinicalTrials.gov.

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