Effect of NovoTTF-100A Together With Temozolomide in Newly Diagnosed Glioblastoma Multiforme (GBM)
Public ClinicalTrials.gov record NCT00916409. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Prospective, Multi-center Trial of NovoTTF-100A Together With Temozolomide Compared to Temozolomide Alone in Patients With Newly Diagnosed GBM.
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The study is a prospective, randomly controlled pivotal trial, designed to test the efficacy and safety of a medical device, the NovoTTF-100A, as an adjuvant to the best standard of care in the treatment of newly diagnosed GBM patients. The device is an experimental, portable, battery operated device for chronic administration of alternating electric fields (termed TTFields or TTF) to the region of the malignant tumor, by means of surface, insulated electrode arrays.
Study identification
- NCT ID
- NCT00916409
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 700 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jun 2009 (Type not available)
- Primary completion
- Dec 2016 (Actual)
- Completion
- Mar 2017 (Actual)
- Last update posted
- Apr 10, 2017
2009 – 2017
United States locations
- U.S. sites
- 41
- U.S. states
- 21
- U.S. cities
- 33
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama at Birmingham | Birmingham | Alabama | 35294-3410 | — |
| Barrow Neurology Clinics | Phoenix | Arizona | 85013 | — |
| City of Hope | Duarte | California | 91010-3000 | — |
| University of California San Diego Moores Cancer Center (UCSD) | La Jolla | California | 92093 | — |
| University of Southern California (USC) | Los Angeles | California | 90033 | — |
| University of Colorado Denver | Aurora | Colorado | 80045 | — |
| UF Health Cancer Center at Orlando Health | Orlando | Florida | 32806 | — |
| H. Lee Moffitt Cancer Center & Research Institute | Tampa | Florida | 33612 | — |
| Emory University, Winship Cancer Institute | Atlanta | Georgia | 30322 | — |
| University of Illinois at Chicago (UIC) | Chicago | Illinois | 60612 | — |
| University of Kentucky, Markey Cancer Center | Lexington | Kentucky | 40536-0093 | — |
| Norton Cancer Institute | Louisville | Kentucky | 40202 | — |
| Maine Medical Center | Scarborough | Maine | 04074 | — |
| The Johns Hopkins Hospital | Baltimore | Maryland | 21287 | — |
| Tufts Medical Center | Boston | Massachusetts | 02111 | — |
| Beth Israel Deaconess Medical Center | Boston | Massachusetts | 02215 | — |
| Lahey Clinic Medical Center | Burlington | Massachusetts | 01805 | — |
| Henry Ford Health System | Detroit | Michigan | 48202 | — |
| Washington University School of Medicine, Division of Oncology | St Louis | Missouri | 63110 | — |
| New Jersey Neuroscience Center - JFK Medical Center | Edison | New Jersey | 08818 | — |
| John Theurer Cancer Center at Hackensack University Medical Center | Hackensack | New Jersey | 07601 | — |
| Weill Cornell Medical College | New York | New York | 10021 | — |
| Mount Sinai Medical Center, Department of Neurosurgery | New York | New York | 10029 | — |
| Columbia University Medical Center | New York | New York | 10032 | — |
| University of North Carolina | Chapel Hill | North Carolina | 27599 | — |
| Cleveland Clinic Taussig Cancer Center | Cleveland | Ohio | 44195 | — |
| The Ohio State University Arthur G. James Cancer Hospital and Solove Research Institute | Columbus | Ohio | 43210 | — |
| Geisinger Health System | Danville | Pennsylvania | 17822 | — |
| Hospital of the University of Pennsylvania | Philadelphia | Pennsylvania | 19104 | — |
| Pennsylvania Hospital | Philadelphia | Pennsylvania | 19104 | — |
| University of Pittsburgh Medical Center (UPMC) | Pittsburgh | Pennsylvania | 15232 | — |
| UT Southwestern Medical Center | Dallas | Texas | 75235-8808 | — |
| Baylor | Dallas | Texas | 75246 | — |
| Methodist Hospital | Houston | Texas | 77030 | — |
| Methodist Neurological Institute | Houston | Texas | 77030 | — |
| The University of Texas Health Science Center at Houston (UTHSC) | Houston | Texas | 77030 | — |
| Scott and White Healthcare | Temple | Texas | 76508 | — |
| Memorial Hermann The Woodlands | The Woodlands | Texas | 77380 | — |
| University of Virginia Health System | Charlottesville | Virginia | 22908 | — |
| Swedish Neuroscience Institute | Seattle | Washington | 98122 | — |
| University of Washington/Seattle Cancer Care Alliance | Seattle | Washington | 98195 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 48 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00916409, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 10, 2017 · Synced Oct 19, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00916409 live on ClinicalTrials.gov.