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Completed Phase 2 Interventional Results available

Open-label Study to Evaluate the Safety, PK, and PD of MEK Inhibitor GSK1120212 in Subjects With Relapsed or Refractory Leukemias

ClinicalTrials.gov ID: NCT00920140

Public ClinicalTrials.gov record NCT00920140. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced May 16, 2026, 11:53 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

An Open-Label, Dose-Escalation, Phase I/II Study to Investigate the Safety, Pharmacokinetics, Pharmacodynamics, and Clinical Activity of the MEK Inhibitor GSK1120212 in Subjects With Relapsed or Refractory Leukemias

Study identification

NCT ID
NCT00920140
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
GlaxoSmithKline
Industry
Enrollment
97 participants

Conditions and interventions

Conditions

Interventions

  • GSK1120212 Drug

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Apr 30, 2011
Primary completion
Mar 31, 2013
Completion
Mar 31, 2013
Last update posted
Apr 1, 2014

2011 – 2013

United States locations

U.S. sites
15
U.S. states
10
U.S. cities
15
Facility City State ZIP Site status
GSK Investigational Site Birmingham Alabama 35249
GSK Investigational Site Duarte California 91010
GSK Investigational Site Los Angeles California 90095
GSK Investigational Site San Francisco California 94143
GSK Investigational Site Chicago Illinois 60611
GSK Investigational Site Rochester Minnesota 55905
GSK Investigational Site Bornx New York 10467
GSK Investigational Site Lake Success New York 11042
GSK Investigational Site New York New York 10032
GSK Investigational Site Winston-Salem North Carolina 27157-1009
GSK Investigational Site Portland Oregon 97239
GSK Investigational Site Hershey Pennsylvania 17033
GSK Investigational Site Pittsburgh Pennsylvania 15232
GSK Investigational Site Houston Texas 77030
GSK Investigational Site Seattle Washington 98109-1023

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 13 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00920140, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Apr 1, 2014 · Synced May 16, 2026

Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.

Open the official record

The complete protocol, eligibility criteria, and contact information for NCT00920140 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →