Efficacy, Safety, and Tolerability of SPD489 in Adults With Schizophrenia and Predominant Negative Symptoms
Public ClinicalTrials.gov record NCT00922272. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2, Multicenter Study With Open-label & Randomized Double-blind Placebo-controlled Withdrawal Phases to Evaluate the Efficacy, Safety, & Tolerability of SPD489 in Adults With Schizophrenia & Predominant Negative Symptoms Who Are Clinically Stable & Taking Stable Doses of Atypical Antipsychotic Medication
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
To explore the efficacy of SPD489, as adjunctive therapy to a stable dose of atypical antipsychotic medication, on negative symptoms in adult subjects with clinically stable schizophrenia and predominant negative symptoms, as measured by the Scale for the Assessment of Negative Symptoms (SANS).
Study identification
- NCT ID
- NCT00922272
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 92 participants
Conditions and interventions
Interventions
- SPD489 (lisdexamfetamine dimesylate) Drug
- Placebo matching SPD489 (lisdexamfetamine dimesylate) Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years to 55 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Sep 14, 2009 (Actual)
- Primary completion
- Jan 20, 2011 (Actual)
- Completion
- Jan 20, 2011 (Actual)
- Last update posted
- Jun 9, 2021
2009 – 2011
United States locations
- U.S. sites
- 27
- U.S. states
- 11
- U.S. cities
- 24
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| K&S Professional Research Services | Little Rock | Arkansas | 72201 | — |
| South Coast Clinical Trials | Anaheim | California | 92804 | — |
| Omega Clinical Trials | Anaheim | California | 92805 | — |
| Clinical Innovations | Costa Mesa | California | 92626 | — |
| Collaborative Neuroscience Network, Inc. | Garden Grove | California | 92845 | — |
| Apostle Clinical Trials, Inc. | Long Beach | California | 90813 | — |
| Excell Research, Inc. | Oceanside | California | 92056 | — |
| Southcoast Clinical Trials | San Bernardino | California | 92405 | — |
| CNRI San Diego & Los Angeles | San Diego | California | 92102 | — |
| Affiliated Research Institute | San Diego | California | 92108 | — |
| Artemis Institute for Clinical Research | San Diego | California | 92123 | — |
| Neuropsychiatric Research Center of Orange County | Santa Ana | California | 92701 | — |
| Accurate Clinical Trials | Kissimmee | Florida | 34741 | — |
| Behavioral Clinical Research, INC | Lauderhill | Florida | 33319 | — |
| Segal Institute for Clinical Research (Miami) | North Miami | Florida | 33161 | — |
| Medical Research Group of Central Florida | Orange City | Florida | 32763 | — |
| Stedman Clinical Trials | Tampa | Florida | 33613 | — |
| Comprehensive NeuroScience | Atlanta | Georgia | 30328 | — |
| Uptown Research Institute | Chicago | Illinois | 60640 | — |
| J. Gary Booker, MD, APMC | Shreveport | Louisiana | 71104 | — |
| CRI Worldwide, LLC. | Willingboro | New Jersey | 08046 | — |
| Advanced Bio-Behavioral Sciences | Elmsford | New York | 10523 | — |
| Comprehensive Neuroscience, Inc. | Hollis | New York | 11423 | — |
| University of Cincinnati | Cincinnati | Ohio | 45219 | — |
| CRI Worldwide | Philadelphia | Pennsylvania | 19139 | — |
| Community Clinical Research, Inc. | Austin | Texas | 78756 | — |
| University Hills Clinical Research | Irving | Texas | 75062 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00922272, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jun 9, 2021 · Synced Oct 24, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00922272 live on ClinicalTrials.gov.