An Extension Protocol for Multiple Sclerosis Patients Who Participated in Genzyme-Sponsored Studies of Alemtuzumab
Public ClinicalTrials.gov record NCT00930553. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This open-label, rater-blinded extension study enrolled participants who had relapsing-remitting multiple sclerosis (RRMS) and who participated in one of three prior Genzyme-sponsored studies of alemtuzumab (CAMMS223 \[NCT00050778\], CAMMS323 \[NCT00530348\] also known as CARE-MS I, or CAMMS324 \[NCT00548405\] also known as CARE-MS II). The purposes of this study were: 1. To examine the long term safety and efficacy of alemtuzumab treatment in participants who received alemtuzumab as their study treatment in one of the prior studies. 2. To examine the safety and efficacy of initial alemtuzumab treatment in this study for participants who received Rebif® (interferon beta-1a) as their study treatment in one of the prior studies. 3. To determine the safety and efficacy of additional "as needed" alemtuzumab treatment courses. This applied both to participants who received alemtuzumab for the first time in one of the prior studies or for the first time in this extension study.
Study identification
- NCT ID
- NCT00930553
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 1,314 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- Not listed
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Aug 2009 (Type not available)
- Primary completion
- Feb 2016 (Actual)
- Completion
- Feb 2016 (Actual)
- Last update posted
- May 15, 2017
2009 – 2016
United States locations
- U.S. sites
- 69
- U.S. states
- 31
- U.S. cities
- 63
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| North Central Neurology Associates, P.C. | Cullman | Alabama | — | — |
| HOPE Research Institute | Phoenix | Arizona | — | — |
| St. Joseph's Hospital and Medical Center Barrow Neurology Clinics - Barrow Neurological Institute | Phoenix | Arizona | — | — |
| Mayo Clinic Arizona (Scottsdale) | Scottsdale | Arizona | — | — |
| Northwest NeuroSpecialists, PLLC | Tucson | Arizona | — | — |
| East Bay Physicians Medical Group/ Sutter East Bay Medical Foundation | Berkeley | California | — | — |
| Neurology Center North Orange County | La Habra | California | — | — |
| University of Southern California Keck School of Medicine/University of Southern California LAC & USC Medical Center | Los Angeles | California | — | — |
| Neuro-Therapeutics, Inc. | Pasadena | California | — | — |
| Stanford University Medical Center | Stanford | California | — | — |
| University of Colorado Health Science Center - Aurora | Aurora | Colorado | — | — |
| Advanced Neurology of Colorado | Fort Collins | Colorado | — | — |
| Yale MS Research Center | New Haven | Connecticut | — | — |
| The George Washington University Medical Faculty Associates | Washington D.C. | District of Columbia | — | — |
| University of Florida Neuroscience Institute | Jacksonville | Florida | — | — |
| Neurology Associates, P.A. | Maitland | Florida | — | — |
| Neurological Associates | Pompano Beach | Florida | — | — |
| Negroski, Stein, Sutherland and Hanes Neurology | Sarasota | Florida | — | — |
| Axiom Clinical Research of Florida | Tampa | Florida | — | — |
| University of South Florida College of Medicine | Tampa | Florida | — | — |
| Emory University Department of Neurology | Atlanta | Georgia | — | — |
| Shepherd Center Multiple Sclerosis Institute | Atlanta | Georgia | — | — |
| University of Chicago Medical Center | Chicago | Illinois | — | — |
| Consultants in Neurology, LTD | Northbrook | Illinois | — | — |
| Fort Wayne Neurological Center | Fort Wayne | Indiana | — | — |
| Indiana University Multiple Sclerosis Center | Indianapolis | Indiana | — | — |
| Iowa Health Physicians | Des Moines | Iowa | — | — |
| Ruan Neurology Clinic and Clinical Research Center, Mercy Medical Center | Des Moines | Iowa | — | — |
| University of Kansas Medical Center, Department of Neurology | Kansas City | Kansas | — | — |
| MidAmerica Neuroscience Institute | Lenexa | Kansas | — | — |
| Associates in Neurology, P.S.C. | Lexington | Kentucky | — | — |
| Kentucky Neuroscience Research | Louisville | Kentucky | — | — |
| University of Maryland, Maryland Center for MS | Baltimore | Maryland | — | — |
| The MS Center at St. Elizabeth's | Boston | Massachusetts | — | — |
| UMass Memorial Medical Center | Worcester | Massachusetts | — | — |
| University of Michigan Medical School | Ann Arbor | Michigan | — | — |
| Michigan Neurology Association | Clinton | Michigan | — | — |
| Wayne State University, The School of Medicine, Department of Neurology | Detroit | Michigan | — | — |
| Spectrum Health Medical Group, Neurology/Michigan Medical P.C., West Michigan MS Clinic | Grand Rapids | Michigan | — | — |
| Northern Michigan Neurology | Traverse City | Michigan | — | — |
| Saint Luke's Brain & Stroke Institute | Kansas City | Missouri | — | — |
| Renown Institute for Neurosciences | Reno | Nevada | — | — |
| Dartmouth Hitchcock Medical Center | Lebanon | New Hampshire | — | — |
| MS Center at Holy Name Hospital | Teaneck | New Jersey | — | — |
| University of New Mexico, Dept. of Neurology | Albuquerque | New Mexico | — | — |
| Empire Neurology P.C. | Latham | New York | — | — |
| Winthrop University Hospital Multiple Sclerosis Treatment Center | Mineola | New York | — | — |
| MS Care Center at NYUMC and HJD | New York | New York | — | — |
| The Corinne Goldsmith Dickinson Center for Multiple Sclerosis at Mount Sinai | New York | New York | — | — |
| South Shore Neurologic Associates, P.C. | Patchogue | New York | — | — |
| Rochester Multiple Sclerosis Center | Rochester | New York | — | — |
| SUNY Upstate Medical University, Department of Neurology | Syracuse | New York | — | — |
| The University of North Carolina at Chapel Hill | Chapel Hill | North Carolina | — | — |
| Wake Forest University Health Science Department of Neurology | Winston-Salem | North Carolina | — | — |
| Cleveland Clinic Foundation | Cleveland | Ohio | — | — |
| Oak Clinic for Multiple Sclerosis | Uniontown | Ohio | — | — |
| OMRF Multiple Sclerosis Center of Excellence | Oklahoma City | Oklahoma | — | — |
| Lehigh Valley Hospital Neurosciences and Pain Research | Allentown | Pennsylvania | — | — |
| Rhode Island Hospital MS Center - The Neurology Foundation, Inc | Providence | Rhode Island | — | — |
| Neurology Clinic PC | Cordova | Tennessee | — | — |
| Advanced Neurosciences Institute | Franklin | Tennessee | — | — |
| Hope Neurology | Knoxville | Tennessee | — | — |
| Vanderbilt University Medical Center | Nashville | Tennessee | — | — |
| Baylor College of Medicine, Maxine Mesinger MS Clinic | Houston | Texas | — | — |
| Central Texas Neurology Consultants | Round Rock | Texas | — | — |
| Integra Clinical Research | San Antonio | Texas | — | — |
| Neurology Center of San Antonio | San Antonio | Texas | — | — |
| MS Center of Greater Washington | Vienna | Virginia | — | — |
| Swedish Medical MS Center | Seattle | Washington | — | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 107 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00930553, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 15, 2017 · Synced Oct 27, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00930553 live on ClinicalTrials.gov.